目的 研究不同联合用药对于腰椎椎管减压术后神经根水肿性疼痛的临床疗效。
方法 选择2013年11月－2014年8月60例行腰椎椎管减压术患者，按照住院奇、偶号随机分为试验组和对照组。试验组采用γ-氨基丁酸（GABA）受体激动剂普瑞巴林胶囊和对乙酰氨基酚缓释片联合用药，对照组单纯予以非甾体类药物塞来昔布胶囊。比较两组术后1周之内疼痛视觉模拟（VAS）评分、睡眠质量（MOS-SS）评分、功能锻炼依从性评分及患者满意度。
结果 试验组与对照组比较，各项评价指标差异有统计学意义（P＜0.05）。
结论 不同联合用药对腰椎椎管减压术后神经根水肿的镇痛效果良好，可获得较好的功能锻炼依从性，同时能提高患者住院体验。
Citation：
李晔, 宁宁, 刘晓艳, 刘欢, 屈俊宏. 不同联合用药对降低腰椎椎管减压术后神经根水肿性疼痛的临床研究. West China Medical Journal, 2015, 30(11): 2109-2111. doi: 10.7507/1002-0179.20150596
Copy
Copyright © the editorial department of West China Medical Journal of West China Medical Publisher. All rights reserved
| 1. |
Quality improvement guidelines for the treatmentof acute pain and cancer pain[J]. JAMA, 1995, 274(23):1874-1880.
|
| 2. |
刘秀萍. 疼痛控制现状及影响因素分析[J]. 华西医学, 2012, 27(10):1595-1597.
|
| 3. |
Cole JC, Dubois D, Kosinski M. Use of patient-reported sleep measures in clinical trials of pain treatment:a literature review and synthesis of current sleep measures and a conceptual model of sleep disturbance in pain[J]. Clin Ther, 2007, 29(Suppl):2580-2588.
|
| 4. |
窦智, 蒋宗滨, 钟进才. MOS-SS睡眠量表用于癌痛患者信度和效度的研究[J]. 中国疼痛医学杂志, 2013, 19(6):341-344.
|
| 5. |
Gordon NF, Gulanick M, Costa F, et al. Physical activity and exercise recommendations for stroke survivors:an american heart association scientific statement from the council on clinical cardiology, subcommittee on exercise, cardiac rehabilitation, and prevention; the council on cardiovascular nursing; the council on nutrition, physical activity, and metabolism; and the stroke council[J]. Stroke, 2004, 35(5):1230-1240.
|
| 6. |
芦凤娟. 乳腺癌患者术后功能锻炼依从性及其影响因素[D]. 广州:中山大学, 2008.
|
| 7. |
谭斌. 腰椎间盘突出症术后复发原因及手术治疗分析[J]. 华西医学, 2013, 28(12):1837-1839.
|
| 8. |
胡雅斌, 顾文飞, 卡哈尔·艾肯木, 等. 腰椎后路椎间融合术后多模式镇痛的效果评价[J]. 新疆医学, 2013, 43(5):31-34.
|
| 9. |
吴在德. 外科学[M]. 北京:人民卫生出版社, 1984:957.
|
| 10. |
Dooley DJ, Taylor CP, Donevan S, et al. Ca2+ Channel alpha2delta ligands:novel modulators of neurotransmission[J]. Trends Pharmacol Sci, 2007, 28(2):75-82.
|
- 1. Quality improvement guidelines for the treatmentof acute pain and cancer pain[J]. JAMA, 1995, 274(23):1874-1880.
- 2. 刘秀萍. 疼痛控制现状及影响因素分析[J]. 华西医学, 2012, 27(10):1595-1597.
- 3. Cole JC, Dubois D, Kosinski M. Use of patient-reported sleep measures in clinical trials of pain treatment:a literature review and synthesis of current sleep measures and a conceptual model of sleep disturbance in pain[J]. Clin Ther, 2007, 29(Suppl):2580-2588.
- 4. 窦智, 蒋宗滨, 钟进才. MOS-SS睡眠量表用于癌痛患者信度和效度的研究[J]. 中国疼痛医学杂志, 2013, 19(6):341-344.
- 5. Gordon NF, Gulanick M, Costa F, et al. Physical activity and exercise recommendations for stroke survivors:an american heart association scientific statement from the council on clinical cardiology, subcommittee on exercise, cardiac rehabilitation, and prevention; the council on cardiovascular nursing; the council on nutrition, physical activity, and metabolism; and the stroke council[J]. Stroke, 2004, 35(5):1230-1240.
- 6. 芦凤娟. 乳腺癌患者术后功能锻炼依从性及其影响因素[D]. 广州:中山大学, 2008.
- 7. 谭斌. 腰椎间盘突出症术后复发原因及手术治疗分析[J]. 华西医学, 2013, 28(12):1837-1839.
- 8. 胡雅斌, 顾文飞, 卡哈尔·艾肯木, 等. 腰椎后路椎间融合术后多模式镇痛的效果评价[J]. 新疆医学, 2013, 43(5):31-34.
- 9. 吴在德. 外科学[M]. 北京:人民卫生出版社, 1984:957.
- 10. Dooley DJ, Taylor CP, Donevan S, et al. Ca2+ Channel alpha2delta ligands:novel modulators of neurotransmission[J]. Trends Pharmacol Sci, 2007, 28(2):75-82.
1/5
WeChat
