目的
总结联合应用封闭式负压引流与人工真皮治疗下肢慢性溃疡的临床效果。
方法
2011年1 月-2012年6月,收治19例下肢慢性溃疡患者。其中男10例,女9例;年龄12~68岁,平均46岁。病因:创伤性溃疡7例,静脉淤血性溃疡3例,动脉供血不足性溃疡1例,神经营养不良性溃疡2例,糖尿病性溃疡6例。病程2个月~3年。创面范围3 cm × 2 cm~12 cm × 9 cm。6例伴骨、肌腱外露。扩创后先行封闭式负压引流培养新鲜肉芽组织,然后移植人工真皮,待类真皮组织形成后移植自体刃厚皮片封闭创面。 结果患者住院时间33~50 d,平均42 d。溃疡均顺利愈合,无严重并发症发生。患者均获随访,随访时间6~24个月。创面皮片色泽良好,质地柔软,耐磨,无明显挛缩或继发功能障碍;溃疡无复发。 结论联合应用封闭式负压引流与人工真皮移植治疗下肢慢性溃疡简便易行、安全有效。
Citation:
张陈威,柳大烈,梁智,刘飞,林海波,郭正东. 封闭式负压引流与人工真皮联合应用治疗下肢慢性溃疡. Chinese Journal of Reparative and Reconstructive Surgery, 2013, 27(8): 1023-1024. doi: 10.7507/1002-1892.20130222
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Copyright © the editorial department of Chinese Journal of Reparative and Reconstructive Surgery of West China Medical Publisher. All rights reserved
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- 1. 王炜. 整形外科学. 杭州: 浙江科学技术出版社, 1999: 1565.
- 2. Wild T, Stremitzer S, Budzanowski A, et al. Definition of efficiency in vacuum therapy—a randomised controlled trial comparing with V. A. C. Therapy. Int Wound J, 2008, 5(5): 641-647.
- 3. 陈欣, 副岛一孝, 野琦斡弘, 等. 成纤维细胞移植促进人工真皮内血管新生的研究. 中国修复重建外科杂志, 2004, 18(3): 205-208.
- 4. Violas P, Abid A, Darodes P, et al. Integra artificial skin in the management of severe tissue defects, including bone exposure, in injured children. J Pediatr Orthop B, 2005, 14(5): 381-384.
- 5. Molnar JA, DeFranzo AJ, Hadaegh A, et al. Acceleration of integra incorporation in complex tissue defects with subatmospheric pressure. Plast Reconstr Surg, 2004, 113(5): 1339-1346.