LI Ling 1,2 , HUANG Jing 1,2 , XU Jing 1,2 , MA Yukui 1 , WU Zhoupeng 1
  • 1. Division of Vascular Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, P. R. China;
  • 2. West China School of Nursing, Sichuan University, Chengdu 610041, P. R. China;
WU Zhoupeng, Email: lzwzp19@163.com
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Objective To investigate association between the nutrition-related indicators and the recurrence of venous thromboembolism (VTE). Methods The clinical data from the patients with VTE receiving 3 or 6 months of anticoagulation therapy at the West China Hospital of Sichuan University, from January 2020 to October 2022, were retrospective analyzed. The multivariate logistic regression analysis was used to assess the association between the nutrition-related indicators such as albumin to fibrinogen ratio (AFR) and prognostic nutrition index (PNI) and VTE recurrence. The test level was set as α=0.05. Results A total of 141 patients with VTE were enrolled, of whom 12 (8.5%) experienced recurrence within 2 years. The multivariate logistic regression analysis identified several risk factors for recurrence, including diabetes [β=–3.368, OR (95%CI)=0.034 (0.001, 0.920), P=0.044], pulmonary embolism [β=–0.454, OR (95%CI)=0.635 (0.423, 0.954), P=0.029], and decreased AFR [β=–0.454, OR (95%CI)=0.635 (0.423, 0.954), P=0.029], but it was not found that the PNI was associated with VTE recurrence [β=–0.153, OR (95%CI)=0.858 (0.722, 1.020), P=0.083]. Conclusion The findings of this study indicate that close monitoring for recurrent VTE is warranted in patients with diabetes mellitus, pulmonary embolism, and decreased AFR receiving anticoagulation therapy.

Citation: LI Ling, HUANG Jing, XU Jing, MA Yukui, WU Zhoupeng. Association between albumin to fibrinogen ratio or prognostic nutrition index and recurrence of venous thromboembolism. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2025, 32(6): 775-778. doi: 10.7507/1007-9424.202412031 Copy

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