Objective To evaluate the usage status of drugs in the treatment of senile cerebral infarction in Xuanwu Hospital of Capital Medical University in 2011, and to provide references for rational usage of drugs for inpatients with senile cerebral infarction.
Methods Medical records of the elderly (≥60 years old) inpatients with cerebral infarction in Xuanwu Hospital in 2011 were collected. ATC codes were used to standardize names of drug and classifications. Patients' general information, number of patients' used drugs, Defined Daily Doses (DDDs), and Drug Utilization Index (DUI) were calculated by using Microsoft Excel 2007 to evaluate the rationality of drugs usage.
Results A total of 430 patients were included. The average age was 70.61±7.29 years old. The average types of diseases were 5.39. The major combined disease was circulatory system disease, accounting for 42.45%. A total of 15 656 medication records were included, involving 243 kinds of drugs (including different administration routes). The average number of used drugs for each patient during the admission was 17.11. The top 5 drugs based on percentage of patients with drug use were Ginkgo Biloba Preparation (injection), clopidogrel (oral), prostaglandin E1 (injection), atorvastatin (oral) and cinepazide (injection). The top 5 drugs of DDDs were Ginkgo Biloba Preparation (injection), ipratropium bromide (inhalation), prostaglandin E1 (injection), folic acid (orla), and clopidogrel (oral). The top 5 drugs of DUI were vitamin B12 (injection), multi-vitamin (oral), nikethamide (injection), methylprednisolone (injection), and vitamin C (oral).
Conclusion For therapeutic drugs used among the elderly patients with cerebral infarction in Xuanwu Hospital of Capital Medical University, the choice, dosage and administration route of medication are rational. However, the drugs with higher DUI are not related with major diseases, which indicates that we should pay attention to the irrational drug use of clinical application, so as to ensure safety, effectiveness and economy of drug application.
Citation：
LIUChen, SHENQian, LIXiao-ling, JIANGDe-chun, LIXing-wei, WANGYu-qin. Drug Utilization Analysis of Elderly Inpatients with Cerebral Infarction in Xuanwu Hospital of Capital Medical University in 2011. Chinese Journal of Evidence-Based Medicine, 2015, 15(10): 1132-1136. doi: 10.7507/1672-2531.20150188
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Copyright © the editorial department of Chinese Journal of Evidence-Based Medicine of West China Medical Publisher. All rights reserved
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刘琛, 王育琴. 首都医科大学宣武医院2011年老年住院患者疾病构成分析. 中国循证医学杂志, 2013, 13(4):385-392.
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中华医学会神经病学分会, 中华医学会神经病学分会脑血管病学组. 中国急性缺血性脑卒中诊治指南2014. 中华神经科杂志, 2015, 48(4):246-257.
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中华医学会神经病学分会, 中华医学会神经病学分会脑血管病学组. 中国缺血性脑卒中和短暂性脑缺血发作二级预防指南2014. 中华神经科杂志, 2015, 48(4):258-273.
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吴廷珫, 刘云海, 胡桂, 等. 脑梗死住院患者用药情况的多中心回顾性调查. 药物流行病学杂志, 2001, 10(3):147-152.
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赵乐萍. 脑梗死住院患者用药情况的回顾性调查. 浙江中医学院学报, 2002, 26(3):80-82.
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杨理会. 脑梗死住院患者用药情况的回顾性调查. 安徽医药, 2004, 8(5):387-388.
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| 7. |
陈树新, 陈翠环. 173例脑梗死住院患者用药分析. 药物流行病学杂志, 2005, 14(5):287-290.
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| 8. |
赵宪荣, 武夏明, 刘伦, 等. 山东省8家医院脑梗死住院患者用药分析. 中国药房, 2005, 16(18):1397-1399.
|
| 9. |
郭忠, 赵晋. 某院2003-2006年急性脑梗死患者用药分析. 中国药房, 2008, 19(11):817-819.
|
| 10. |
李玉媚, 宁剑, 王柳萍, 等. 150例急性脑梗死住院患者用药特点分析. 中国药房, 2015, 26(2):156-159.
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| 11. |
丁建军, 田艳平, 崔向丽, 等. 某院2006-2008年脑梗死住院患者用药情况分析. 药物流行病学杂志, 2009, 18(5):374-375.
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- 1. 刘琛, 王育琴. 首都医科大学宣武医院2011年老年住院患者疾病构成分析. 中国循证医学杂志, 2013, 13(4):385-392.
- 2. 中华医学会神经病学分会, 中华医学会神经病学分会脑血管病学组. 中国急性缺血性脑卒中诊治指南2014. 中华神经科杂志, 2015, 48(4):246-257.
- 3. 中华医学会神经病学分会, 中华医学会神经病学分会脑血管病学组. 中国缺血性脑卒中和短暂性脑缺血发作二级预防指南2014. 中华神经科杂志, 2015, 48(4):258-273.
- 4. 吴廷珫, 刘云海, 胡桂, 等. 脑梗死住院患者用药情况的多中心回顾性调查. 药物流行病学杂志, 2001, 10(3):147-152.
- 5. 赵乐萍. 脑梗死住院患者用药情况的回顾性调查. 浙江中医学院学报, 2002, 26(3):80-82.
- 6. 杨理会. 脑梗死住院患者用药情况的回顾性调查. 安徽医药, 2004, 8(5):387-388.
- 7. 陈树新, 陈翠环. 173例脑梗死住院患者用药分析. 药物流行病学杂志, 2005, 14(5):287-290.
- 8. 赵宪荣, 武夏明, 刘伦, 等. 山东省8家医院脑梗死住院患者用药分析. 中国药房, 2005, 16(18):1397-1399.
- 9. 郭忠, 赵晋. 某院2003-2006年急性脑梗死患者用药分析. 中国药房, 2008, 19(11):817-819.
- 10. 李玉媚, 宁剑, 王柳萍, 等. 150例急性脑梗死住院患者用药特点分析. 中国药房, 2015, 26(2):156-159.
- 11. 丁建军, 田艳平, 崔向丽, 等. 某院2006-2008年脑梗死住院患者用药情况分析. 药物流行病学杂志, 2009, 18(5):374-375.
