目的 探讨成人先天性胆总管囊肿的诊治方法和手术技巧。
方法 对2001年5月至2011年5月期间我院手术治疗的成人先天性胆总管囊肿38例的临床资料进行回顾性分析。
结果 全部病例均行B超和磁共振(MRCP)检查确诊,均行手术治疗。其中7例行急诊囊肿外引流术。行择期手术者中24例行囊肿切除、胆肠吻合术,其中3例合并肝叶切除术; 行内引流术4例; 仅行胆囊切除术3例。囊肿剥除采用点状钳夹、电凝及推剥囊肿黏膜外纤维血管束的办法,不出血,无副损伤。无手术死亡病例,术后恢复顺利。38例患者中术后获随访28例(73.68%),失访10例; 随访时间 3~120个月,平均74个月。24例行囊肿切除者症状消失20例,偶感上腹痛、抗炎治疗后症状可缓解1例,3例失访;11例行内或外引流术者术后近期均有不同程度的胆管炎症状,其中6例于术后2~10 年再手术,另5例失放,6例再手术者中2例术中发现癌变,分别于再手术后2个月和10个月死亡,余4例临床症状消失;3例仅行胆囊切除术者,2例失访,1例仍有反复发作的畏寒、发热及右上腹痛。
结论 B超和MRCP检查有助于明确诊断; 囊肿全切除、肝管空肠Roux-en-Y 吻合术应作为胆总管囊肿的首选术式,囊肿外引流术仅在合并严重感染、全身情况差的患者采用; 手术技巧的改进可为手术提供安全保障。
Citation:
刘崇清,王小非,田云鸿,石刚,盛涛,李敬东,赵国刚,彭祥玉,雷俊阳. Analysis on Diagnosis and Treatment of 38 Adult Patients with Congenital Choledochal Cyst. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2012, 19(1): 102-104. doi:
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Todani T, Watanabe Y, Narusue M, et al. Congenital bile duct cysts: classification, operative procedures, and review of thirty-seven cases including cancer arising from choledochal cyst [J]. Am J Surg, 1977, 134(2): 263-269.
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陈风, 汪健. 胰胆管合流异常及其相关疾病 [J]. 医学综述,2006, 12(3): 179-180..
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Babbitt DP. Congenital choledochal cysts: new etiologial concept based on anomalous relationships of the common bile duct and pancreatic bulb [J]. Ann Radiol (Paris), 1969, 12(3): 231-240.
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4. |
张轶群, 姚礼庆. 先天性胆总管囊肿的诊治进展 [J]. 中国内镜杂志, 2001, 7(3): 34-36..
|
5. |
Imazu M, Ono S, Kimura O, et al. Histological investigations into the difference between cystic and fusiform types of congenital biliary dilatation [J]. Eur J Pediatr Surg, 2003, 13(1): 16-20.
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6. |
Todani T, Watanable Y, Toki A, et al. Carcinoma related to choledochal cysts with internal drainage operations [J]. Surg Gynecol Obstet, 1987, 164(1): 61-64.
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7. |
王果. 先天性胆总管囊肿的治疗 [J]. 临床外科杂志, 1995,3(6): 282-283..
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8. |
闫勇, 蔡忠红, 田伏洲, 等. 胰胆管合流异常致胆总管扩张症的诊断治疗 [J]. 中华肝胆外科杂志, 2005, 11(5): 302-303..
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9. |
陈姬, 李福玉, 向波, 等. 急危重胆总管囊肿的治疗( 附41 例报道) [J]. 中国普外基础与临床杂志, 2005, 12(2): 174-175..
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10. |
Shimura H, Tanaka M, Shimizu S, et al. Laparoscopic treatment of congenital choledochal cyst [J]. Surg Endosc, 1998,12(10): 1268-1271.中国普外基础与临床杂志2012 年1 月第19 卷第1 期 Chin J Bases ? 104 ? Clin General Surg, Vol. 19, No. 1, Jan. 2012.
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11. |
陶开山, 李开宗, 付由池, 等.先天性胆管囊肿的诊治分析 [J].中华外科杂志, 1997, 35(2):17-20..
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12. |
蔡景修. 先天性胆管囊肿的外科治疗 [J]. 中国实用外科杂志, 1995, 15(10):586-588..
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13. |
贾钧, 万远廉, 李龙, 等. 先天性胆总管囊肿85 例临床分析[J].中华普通外科杂志, 2003, 18(9): 550-552..
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14. |
Lilly JR . The surgical treatment of choledochal cyst [J]. Surg Gynecol Obstet, 1979, 149(1): 36-42.
|
15. |
Srimurthy KR, Ramesh S. Laparoscopic management of pediatric choledochal cysts in developing countries: review of ten cases [J]. Pediatr Surg Int, 2006, 22(2): 144-149.
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- 1. Todani T, Watanabe Y, Narusue M, et al. Congenital bile duct cysts: classification, operative procedures, and review of thirty-seven cases including cancer arising from choledochal cyst [J]. Am J Surg, 1977, 134(2): 263-269.
- 2. 陈风, 汪健. 胰胆管合流异常及其相关疾病 [J]. 医学综述,2006, 12(3): 179-180..
- 3. Babbitt DP. Congenital choledochal cysts: new etiologial concept based on anomalous relationships of the common bile duct and pancreatic bulb [J]. Ann Radiol (Paris), 1969, 12(3): 231-240.
- 4. 张轶群, 姚礼庆. 先天性胆总管囊肿的诊治进展 [J]. 中国内镜杂志, 2001, 7(3): 34-36..
- 5. Imazu M, Ono S, Kimura O, et al. Histological investigations into the difference between cystic and fusiform types of congenital biliary dilatation [J]. Eur J Pediatr Surg, 2003, 13(1): 16-20.
- 6. Todani T, Watanable Y, Toki A, et al. Carcinoma related to choledochal cysts with internal drainage operations [J]. Surg Gynecol Obstet, 1987, 164(1): 61-64.
- 7. 王果. 先天性胆总管囊肿的治疗 [J]. 临床外科杂志, 1995,3(6): 282-283..
- 8. 闫勇, 蔡忠红, 田伏洲, 等. 胰胆管合流异常致胆总管扩张症的诊断治疗 [J]. 中华肝胆外科杂志, 2005, 11(5): 302-303..
- 9. 陈姬, 李福玉, 向波, 等. 急危重胆总管囊肿的治疗( 附41 例报道) [J]. 中国普外基础与临床杂志, 2005, 12(2): 174-175..
- 10. Shimura H, Tanaka M, Shimizu S, et al. Laparoscopic treatment of congenital choledochal cyst [J]. Surg Endosc, 1998,12(10): 1268-1271.中国普外基础与临床杂志2012 年1 月第19 卷第1 期 Chin J Bases ? 104 ? Clin General Surg, Vol. 19, No. 1, Jan. 2012.
- 11. 陶开山, 李开宗, 付由池, 等.先天性胆管囊肿的诊治分析 [J].中华外科杂志, 1997, 35(2):17-20..
- 12. 蔡景修. 先天性胆管囊肿的外科治疗 [J]. 中国实用外科杂志, 1995, 15(10):586-588..
- 13. 贾钧, 万远廉, 李龙, 等. 先天性胆总管囊肿85 例临床分析[J].中华普通外科杂志, 2003, 18(9): 550-552..
- 14. Lilly JR . The surgical treatment of choledochal cyst [J]. Surg Gynecol Obstet, 1979, 149(1): 36-42.
- 15. Srimurthy KR, Ramesh S. Laparoscopic management of pediatric choledochal cysts in developing countries: review of ten cases [J]. Pediatr Surg Int, 2006, 22(2): 144-149.