Forty critical patients with respiratory failure in the intensive care unit were randomly divided into two groups,Group A with administration of parenteral nutritino(PN) and Group B,no parenteral nutrition given.Blood gas analysis and respiratory monitoring showed that the respiratory rate,pH、PaO2、PaCO2 and HCO3- had no marked difference between the two groups.But in Group A there was a slight decrease of Pao2/FiO2 and a marked increase of A-aDO2 and the pulmonary shunt.This study indicates that the content of fat emulsion and hydrocarbon in PN may be the main factor that affects the respiratory function.
Citation：
Kang Yan,Wu Yantao,Luo Chuanxing,et al.. THE EFFECT OF PARENTERAL NUTRITION ON PATIENTS WITH RESPIRATIORY DYSFUNCTION. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1997, 4(1): 27-29. doi:
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- 1. Zakinthinos S,Baltopoulos G,Roussos C.Fat emusion and ARDS.Chest,1990;98(2):509.
- 2. Hwang TL,Huang SL,Chen MF.Effects of intravenous fat emulsion on respiratory failure.Chest,1990;97(4):934.
- 3. Green HL,Hazlett D,Demaree R.Relationship between intralipid-induced hyperlipemia and pulmonary function.Am J Clin Nutr,1976;29:127.
- 4. Sundstron G,Zauner CZ,Arborelius M.Decrease in pulmonary diffusing capacity during lipid infusion in healthy men.J Appl Physiol,1973;34:816.
- 5. Kuo PT,Whereat AF.Lipemia as a cause of arterial oxygen unsaturation,and the effect of its control in patients with atherosclerosis.Circulation,1957;16:493.
- 6. Venus B,Smith RA,Patel C,et al.Hemodynamic and gas exchange alterations during intralipid infusion in patients with adult respiratory distress syndrome.Chest,1989;95(6):1278.
- 7. Rubin M,Bilik R,Mor R,et al.Alteration of pulmonary function by filtration of intranenous nutrient mixture.Nutrition,1993;9(2):153.
- 8. Mathru M,Dries DJ,Zecca A,et al.Effect of fast vs slow intralipid infusion on gas exchange,pulmonary hemodynamics,and prostaglandin metabolism.Chest,1991;89(2):426.
