THE PORGANSTIC SIGNIFICANCE OF PROLIFERATIVE CELL NUCLEAR ANTIGEN PROTEIN IN BILE DUCT CARCINOMA_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

Xu Chunsen , Yin Fengzhi , Chen Daliang.

Department of General Surgery,Union Hospital,Fujian Medical University,Fujian 350001;

Corresponding author：

Keywords：

Bile duct neoplasm; Proliferative cell nuclear antigen; Immunohistochemistry; Prognosis

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To study the prognostic significance of proliferative cell nuclear antigen(PCNA)in bile duct carcinoma,expression of PCNA protein was studied immunohistochemically in 30 patients with bile duct carcinoma.Results:86.7 percent of bile duct carcinomas showed PCNA positive staining and significiant difference was observed between malignant and benign tissues.These results suggest that proliferative activity of malignant tissues was ber than that of the benign ones.In patients with cancer of stages 3,the mean survial time for those with high proliferative activity was 13 months in constrast with 26 months for those with low activity.PCNA is of prognostic significance for bile duct carcinoma patients.

Citation： Xu Chunsen,Yin Fengzhi,Chen Daliang.. THE PORGANSTIC SIGNIFICANCE OF PROLIFERATIVE CELL NUCLEAR ANTIGEN PROTEIN IN BILE DUCT CARCINOMA. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1997, 4(2): 81-82. doi: Copy

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CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

THE PORGANSTIC SIGNIFICANCE OF PROLIFERATIVE CELL NUCLEAR ANTIGEN PROTEIN IN BILE DUCT CARCINOMA

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