目的 总结二尖瓣成形术治疗二尖瓣反流患者的临床经验,分析其疗效。 方法 回顾性分析2007 年1 月至 2011 年 7月中国医科大学附属第一医院采用二尖瓣成形术治疗89 例二尖瓣中重度反流患者的临床资料,其中男 51例,女 38 例;年龄21~64 (48.6±13.6)岁;病程1周~21 年。术前经食管超声心动图及术中探查发现二尖瓣中度反流(Ⅲ级) 40 例,重度反流 (Ⅳ级) 49 例。56例二尖瓣脱垂,脱垂病变累及A2区4例、A3区5例、P2区25例、P3区14例,累及多处8例;其中二尖瓣腱索断裂37例,腱索冗长脱垂19例;瓣环扩大42例。手术方式:前叶腱索转移4 例 , 前叶人工腱索 6 例 ,前叶裂缝合2例,交界部缝合 6 例 ,后叶矩形切除加 Sliding (滑行) 技术43 例,后叶折叠缝合成形14例,后叶人工腱索12例,缘对缘成形 10 例和心包补片修补瓣叶穿孔 1 例,其中2种以上修复方式9例。全部患者均使用成形环加固瓣环。手术中应用注水试验和食管超声心动图检查评价成形效果。 结果 无围术期死亡。术后心脏超声心动图提示:二尖瓣无反流 (0 级)15 例,微量反流 (Ⅰ级)41 例,轻度反流 (Ⅱ级) 23 例,轻至中度反流 (Ⅲ级)10 例。所有患者均无二尖瓣狭窄。术后随访77例(86.52%),随访时间3~58 (12.3±18.7) 个月。随访期间1例死于脑血管意外;1例行二尖瓣置换术。 结论 综合运用多种二尖瓣成形技术治疗二尖瓣中重度反流,可获得良好的临床疗效。
Citation:
修宗谊,谷天祥,喻磊,张敏,陈诚. 二尖瓣成形术治疗二尖瓣反流89例临床分析. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2012, 19(6): 676-677. doi:
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- 1. Maisano F, Redaelli A, Pennati G, et al. The hemodynamic effects of double-orifice valve repair for mitral regurgitation:a 3D computational model. Eur J Cardiothorac Surg, 1999, 15 (4):419-425.
- 2. Seeburger J, Borger MA, Doll N, et al. Comparison of outcomes of minimally invasive mitral valve surgery for posterior,anterior and bileaflet prolapse. Eur J Cardiothorac Surg, 2009, 36 (3):532-538.
- 3. 李京倖, 王静, 杜莹, 等. 二尖瓣后叶三角形切除的瓣膜成形术二例. 中国胸心血管外科临床杂志, 2009, 16 (6):507..
- 4. Suri RM, Schaff HV, Dearani JA, et al. Survival advantage and improved durability of mitral repair for leaflet prolapse subsets in the current era. Ann Thorac Surg, 2006, 82 (3):819-826.
- 5. 潘世伟, 胡盛寿, 胡晓鹏, 等. 国产瓣膜成形软环在二尖瓣成形术中的应用. 中国胸心血管外科临床杂志, 2011, 18 (1):26-29..
- 6. 王铁征, 徐方杰, 郑悦, 等. 三种二尖瓣人工成形环的临床效果. 中华胸心血管外科杂志, 2010, 26 (3):200-201..
- 7. Chang BC, Youn YN, Ha JW, et al. Long-term clinical results of mitral valvuloplasty using flexible and rigid rings:a prospective and randomized study. J Thorac Cardiovasc Surg, 2007, 133 (4):995-1003.
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