• Institute of Orthopaedics and Traumatology;;
  • Fourth Military Medical University. Xian. 710032;;
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In 50 animals, 100 nerve injections were carried out by using four drugs and the physiological saline was used as control. The pathological alterations in the nerve were evident as early as 1 hour after injection with splitting of the myelin larnellae in local areas. At 24 hours, there were areas of complete delamination and fragmentetion of the myelin sheath. Some axons had completely disintegreted. A remarkable reduction in the amplitude of nerve-muscle action potentials was indicative of early ncurophysiological changes in this type of nerve injury and the detection of this was conducive to its early diagnosis..

Citation: Zhu Qingsheng,et al.. PERIPHERAL NERVE INJECTION INJURY: AN EXPERIMENTAL STUDY OF EARLY CHANGES IN HISTOLOGY AND ELECTROPHYSIOLOGY. Chinese Journal of Reparative and Reconstructive Surgery, 1991, 5(4): 232-234. doi: Copy

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