Objective To investigate the effect of the duct-to-mucosa anastomosis in invaginating end-to-side pancreaticojejunostomy.
Methods A retrospective review was conducted for 200 patients treated with pancreaticoduod-enectomy (PD) between August 2005 and December 2012. Reconstruction of digestive tract in PD was done according to the method described by Child. The duct-to-mucosa anastomosis was applied in the invaginating end-to-side pancrea-ticojejunostomy. The outline of the anastomosis structures was as follows:anastomosis of pancreatic duct and jejunal mucosa, anastomosis of pancreatic and jejunal resection margin, and anastomosis of pancreas and jejunal seromuscular layer. A cilicone tube was put into the pancreatic duct and lead to the jejunum. The anastomotic stoma was covered with part of the omentum majus, and put a drainage tube under the anastomotic stoma.
Results The operation went smoothly,and no deaths occurred during perioperative period. The surgical time was 280-420 min, the average time was (298±77) min. The pancreatic fistula were observed in 22 patients (11%), including 17 patients in Grade A, 2 patients in Grade B, and 3 patients in Grade C. The other complications were observed in 19 patients, including 16 patients with addominal infection, 1 patient with bleeding from splenic vein, 1 patient with bleeding from ruptured of pseudoaneurysm at biliary intestinal anastomosis, 1 patient with abdominal abscess. Three patients with pancreatic fistula in Grade C were cured by reoperation, and the other patients with pancreatic fistula were cured by expectant treatment.
Conclusions The duct-to-mucosa anastomosis in invaginating end-to-side pancreaticojejunostomy is a simple and safe procedure that has the advantage in reducing the incidence of the pancreatic fistula. Using omentum to cover the anastomotic could localize the diffusion of panreactic fistula, and reduce the incidence of serious complications caused by pancreatic fistula.
Citation:
YANG Yuanyuan,HUANG Heguang,CHEN Yanchang,LU Fengchun,LIN Xianchao,LIN Ronggui. Application of Duct-to-Mucosa Anastomosis in Invaginating End-to-Side Pancreaticojejunostomy: An Analysis of 200 Cases. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2013, 20(7): 724-727. doi:
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Balcom JH 4th, Rathner DW, Warshaw AL, et a1. Ten-yearexperience with 733 pancreatic resections: changing indications, old patients, and decreasing length hospitalization[J]. Arch Surg, 2001, 136(4): 391-398..
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Bassi C, Dervenis C, Butturini G, et a1. Postoperative pancreaticfistula:an international study group (ISGPF) definition[J].Surgery, 2005, 138(1): 8-13..
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Reid-Lombardo KM, Farnell MB, Crippa S, et a1. Pancreatic anastomotic leakage after ancreaticoduodenectomy in 1 507 patients:a report from the Pancreatic Anastomotic Leak Study Group[J]. J Gastrointest Surg, 2007, 11(11): 1451-1458..
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李海民, 窦科蜂, 宋振顺, 等. 套人式双层连续缝合加捆绑在胰肠吻合术中的应用[J]. 中国普外基础与临床杂志, 2007, 14(4): 480..
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张春秋, 王国华, 彭晓晖, 等. 捆绑式胰肠吻合术在预防胰十二指肠切除术后胰瘘发生中的临床应用[J]. 中国普外基础与临床杂志, 2008, 15(8): 565-566..
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彭淑牖, 牟一平, 江献川, 等. 胰断端空肠浆肌鞘内套入吻合术[J]. 中国实用外科杂志, 1996, 16(10): 596-598.
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Peng SY, Mou YP, Cai XJ, et a1. Binding pancreaticojejunostomy is a new technique to minimize leakage[J]. Am J Surg, 2002, 183(3): 283-285..
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彭淑牖, 刘颖斌, 牟一平, 等. 捆绑式胰肠吻合术100例报告[J]. 胰腺病学杂志, 2001, 1(1): 43-45.
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彭淑牖, 牟一平, 蔡秀军, 等. 捆绑式胰肠吻合术51例报告[J]. 外科理论与实践, l998, 3(2): 117-118.
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12. |
彭淑牖, 吴育连, 彭承宏, 等. 一种确保不发生胰瘘的术式—捆绑式胰肠吻合术[J]. 普外基础与临床杂志, 1997, 4(4): 242-243.
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倪泉兴. 胰十二指肠切除术胰肠重建的基本要求和吻合方式选择[J]. 中华肝胆外科杂志, 2011, 17(11):876-878.
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Bai MD, Rung LQ, Wang LC, et a1. Experimental study onoperative methods of pancreaticojejunostomy with reference to anastomotic patency and postoperative pancreatic exocrine function[J]. World J Gastroenterol, 2008, 14(3):441-447..
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15. |
Okamoto A, Tsuruta K. Fistulation method:simple and safe pancreaticojejunostomy after pancreatoduodenectomy[J]. Surgery, 2000, 127(4):433-438..
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16. |
刘双海, 李浩, 王忠, 等. 胰十二指肠切除术中不同胰肠吻合方式的疗效比较[J]. 中华消化外科杂志, 2007, 6(4):312-315.
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17. |
高乃荣, 石欣, 胡浩霖. 胰肠插入式荷包式吻合术防胰瘘效果的临床观察[J]. 中华肝胆外科杂志, 2003, 9(3):182-183..
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18. |
孙建民, 徐海涛, 张玉宝. 胰管肠黏膜吻合在胰十二指肠切除术中的临床应用[J]. 肝胆胰外科杂志, 2012, 24(4):322-324.
|
19. |
朱学锋, 陈益君. 胰十二指肠切除术中胰肠吻合的历史与研究现状[J]. 肝胆外科杂志, 2012, 20(4):311-313.
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20. |
Peng SY, Mou YP, Liu YB, et a1. Binding pancreaticojejunostomy:150 consecutive cases without leakage[J]. J Gastrointest Surg, 2003, 7(7):898-900.
|
21. |
吴诚义, 任国胜, 竺东长, 等. 捆绑式胰肠吻合术的改良(附8例报告)[J]. 中国普外基础与临床杂志, 2003; 10(6):553-554.
|
22. |
Kapoor VK, Sharma A, Behari A, et a1. Omental flaps in pancr-eaticoduodenectomy[J]. JOP, 2006, 7(6):608-615.
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23. |
Maeda A, Ebata T, Kanemoto H, et a1. Omental flap in pancreaticoduodenectomyfor protection of splanchnic vessels[J]. World J Surg, 2005, 29(9):1122-1126.
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24. |
张弘炜, 王太洪. 胰十二指肠切除术后不同胰肠吻合方式的效果与评价[J]. 肝胆外科杂志, 2012, 20(2):91-93.
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- 1. Berger AC, Howard TJ, Kennedy EP, et a1. Does type of pancr-eaticojejunostonly after pancreaticoduodenectomy decrease rate of pancreatic fistula? A randomized, prospective, dual-institutiontIial[J]. J Am Coll Surg, 2009, 208(5): 738-749..
- 2. Cameron JL, Pitt HA, Yeo CJ, et a1. One hundred and forty-five consecutive pancreaticoduodenectomies without mortality[J]. Ann Surg, 1993, 217(5): 430-435.
- 3. Balcom JH 4th, Rathner DW, Warshaw AL, et a1. Ten-yearexperience with 733 pancreatic resections: changing indications, old patients, and decreasing length hospitalization[J]. Arch Surg, 2001, 136(4): 391-398..
- 4. Bassi C, Dervenis C, Butturini G, et a1. Postoperative pancreaticfistula:an international study group (ISGPF) definition[J].Surgery, 2005, 138(1): 8-13..
- 5. Reid-Lombardo KM, Farnell MB, Crippa S, et a1. Pancreatic anastomotic leakage after ancreaticoduodenectomy in 1 507 patients:a report from the Pancreatic Anastomotic Leak Study Group[J]. J Gastrointest Surg, 2007, 11(11): 1451-1458..
- 6. 李海民, 窦科蜂, 宋振顺, 等. 套人式双层连续缝合加捆绑在胰肠吻合术中的应用[J]. 中国普外基础与临床杂志, 2007, 14(4): 480..
- 7. 张春秋, 王国华, 彭晓晖, 等. 捆绑式胰肠吻合术在预防胰十二指肠切除术后胰瘘发生中的临床应用[J]. 中国普外基础与临床杂志, 2008, 15(8): 565-566..
- 8. 彭淑牖, 牟一平, 江献川, 等. 胰断端空肠浆肌鞘内套入吻合术[J]. 中国实用外科杂志, 1996, 16(10): 596-598.
- 9. Peng SY, Mou YP, Cai XJ, et a1. Binding pancreaticojejunostomy is a new technique to minimize leakage[J]. Am J Surg, 2002, 183(3): 283-285..
- 10. 彭淑牖, 刘颖斌, 牟一平, 等. 捆绑式胰肠吻合术100例报告[J]. 胰腺病学杂志, 2001, 1(1): 43-45.
- 11. 彭淑牖, 牟一平, 蔡秀军, 等. 捆绑式胰肠吻合术51例报告[J]. 外科理论与实践, l998, 3(2): 117-118.
- 12. 彭淑牖, 吴育连, 彭承宏, 等. 一种确保不发生胰瘘的术式—捆绑式胰肠吻合术[J]. 普外基础与临床杂志, 1997, 4(4): 242-243.
- 13. 倪泉兴. 胰十二指肠切除术胰肠重建的基本要求和吻合方式选择[J]. 中华肝胆外科杂志, 2011, 17(11):876-878.
- 14. Bai MD, Rung LQ, Wang LC, et a1. Experimental study onoperative methods of pancreaticojejunostomy with reference to anastomotic patency and postoperative pancreatic exocrine function[J]. World J Gastroenterol, 2008, 14(3):441-447..
- 15. Okamoto A, Tsuruta K. Fistulation method:simple and safe pancreaticojejunostomy after pancreatoduodenectomy[J]. Surgery, 2000, 127(4):433-438..
- 16. 刘双海, 李浩, 王忠, 等. 胰十二指肠切除术中不同胰肠吻合方式的疗效比较[J]. 中华消化外科杂志, 2007, 6(4):312-315.
- 17. 高乃荣, 石欣, 胡浩霖. 胰肠插入式荷包式吻合术防胰瘘效果的临床观察[J]. 中华肝胆外科杂志, 2003, 9(3):182-183..
- 18. 孙建民, 徐海涛, 张玉宝. 胰管肠黏膜吻合在胰十二指肠切除术中的临床应用[J]. 肝胆胰外科杂志, 2012, 24(4):322-324.
- 19. 朱学锋, 陈益君. 胰十二指肠切除术中胰肠吻合的历史与研究现状[J]. 肝胆外科杂志, 2012, 20(4):311-313.
- 20. Peng SY, Mou YP, Liu YB, et a1. Binding pancreaticojejunostomy:150 consecutive cases without leakage[J]. J Gastrointest Surg, 2003, 7(7):898-900.
- 21. 吴诚义, 任国胜, 竺东长, 等. 捆绑式胰肠吻合术的改良(附8例报告)[J]. 中国普外基础与临床杂志, 2003; 10(6):553-554.
- 22. Kapoor VK, Sharma A, Behari A, et a1. Omental flaps in pancr-eaticoduodenectomy[J]. JOP, 2006, 7(6):608-615.
- 23. Maeda A, Ebata T, Kanemoto H, et a1. Omental flap in pancreaticoduodenectomyfor protection of splanchnic vessels[J]. World J Surg, 2005, 29(9):1122-1126.
- 24. 张弘炜, 王太洪. 胰十二指肠切除术后不同胰肠吻合方式的效果与评价[J]. 肝胆外科杂志, 2012, 20(2):91-93.