Objective To evaluate the imaging features of pancreatic neuroendocrine carcinoma （PNEC）.
Methods The imaging data of 7 patients with PNECs proved by surgery and pathology in West China Hospital of Sichuan University from Jul. 2007 to Dec. 2012 were retrospectively analyzed. The boundary， density， and strengthening features of tumor were observed.
Results Seven tumors were found in all patients with 2 in pancreatic head， body， and tail， respectively. There was 1 tumor in pancreatic body and tail too. Five tumors were with unclear boundary. Five tumors had hypodense enhancement and 2 had isodense enhancement. Two cases had distal pancreatic duct dilation. None of them had liver metastases or lymph node involvement.
Conclusion PNEC has certain characteristics on imaging. It is difficult to distinguish diagnosis from pancreatic cancer.
Citation：
LIU Xijiao,WANG Weiya,HUANG Zixing,LI Li,YAO Wenqing,SONG Bin.. Imaging of Pancreatic Neuroendocrine Carcinoma. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2012, 19(10): 1126-1129. doi:
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Copyright © the editorial department of CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY of West China Medical Publisher. All rights reserved
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- 1. Lewis RB， Lattin GE， Paal E. Pancreatic endocrine tumors：radiologic-clinicopathologic correlation[J]. Radiographics， 2010， 30(6)： 1445-1464.
- 2. Schima W， Ba-Ssalamah A， Kolblinger C， et al. Pancreaticadenocarcinoma[J]. Eur Radiol， 2007， 17(3)： 638-649.
- 3. Ku YM， Shin SS， Lee CH， et al. Magnetic resonance imaging of cystic and endocrine pancreatic neoplasms[J]. Top MagnReson Imaging ， 2009， 20(1)：11-18.
- 4. Takaji R， Matsumoto S， Mori H， et al. Carcinoid tumors of the pancreas：dynamic CT and MRI features with pathological corre-lation[J]. Abdom Imaging， 2009， 34(6)：753-758.
- 5. Hamada Y， Nakayama Y， Maeshiro K， et al. Two cases of primary carcinoid tumor of the pancreas associated with marked stenosis of the main pancreatic duct[J]. Pancreas， 2009， 38(7)：834-835.
- 6. Yamamoto M， Miyagawa K， Hiura M， et al. Poorly differentiated neuroendocrine carcinoma of the pancreas responsive to combination therapy with gemcitabine and S-1[J]. Intern Med， 2012， 51(7)：727-732.
- 7. Schueller G， Schima W， Schueller-Weidekamm C， et al. Multidetector CT of pancreas： effects of contrast material flow rate and individualized scan delay on enhancement of pancreas and tumor contrast[J]. Radiology， 2006， 241(2)： 441-448.
- 8. Klimstra DS， Modlin IR， Adsay NV， et al. Pathology reporting of neuroendocrine tumors： application of the Delphic consensus process to the development of a minimum pathology data set[J]. Am J Surg Pathol， 2010， 34(3)： 300-313.
- 9. Owen NJ， Sohaib SA， Peppercorn PD， et al. MRI of pancreatic neuroendocrine tumours[J]. Br J Radiol， 2001， 74(886)： 968-973.
- 10. Debray MP， Geoffroy O， Laissy JP， et al. Imaging appearances of metastases from neuroendocrine tumours of the pancreas[J]. Br J Radiol， 2001， 74(887)： 1065-1070.
- 11. Yoon SH， Lee JM， Cho JY， et al. Small (≤20 mm) pancreatic adenocarcinomas： analysis of enhancement patterns and secondary signs with multiphasic multidetector CT[J]. Radiology， 2011， 259(2)： 442-452.
- 12. Spencer JA， Ward J， Guthrie JA， et al. Assessment of resecta-bility of pancreatic cancer with dynamic contrast-enhanced MR imaging：technique， surgical correlation and patient outcome[J].Eur Radiol， 1998， 8(1)： 23-29.
- 13. Sai M， Mori H， Kiyonaga M， et al. Peripancreatic lymphatic invasion by pancreatic carcinoma： evaluation with multi-detector row CT[J]. Abdom Imaging， 2010， 35(2)： 154-162.
