Objective To explore the donor maintenance points of donor donation after brain death (DBD).
Methods From December 2011 to January 2012,two cases of organ DBD in our hospital were performed. After diagnosis of brain death,mechanical ventilation,fluid resuscitation,vasoactive drugs,inotropic drugs,and so on were used,and invasive arterial pressure, central venous pressure,heart rate,blood gas exchange,urine output,electrolyte and acid-base balance,body temperature, hematocrit,albumin level were monitored,the donors vital organ perfusion were successfully kept at acceptable level.
Results The vital signs of two cases of DBD donors were stable. The livers,kidneys,and corneas were donated,and the functions were stable and normal. Case one was diagnosed for brain death 6h after ICU admitted,the period from diagnosis to organ procurement was 33h. Case two was diagnosed for brain death 8h after ICU admitted,the period from diagnosis to organ procurement was 31h. All transplanted organs,livers,kidneys,and corneas,were working well after operation.
Conclusions Donor maintenance process of DBD is the cornerstone to ensuring successfully organ donation and transplantation,which is important to improve the utilization rate of donated organs,and release the severely shortage of organ.
Citation:
ZHOU Zhigang,LI Chao,LI Li,WANG Yinjia,DONG Quan,ZHENG Pengxiao,.. Donor Maintenance of Organ Donation after Brain Death (Report of 2 Cases). CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2012, 19(5): 486-489. doi:
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1. |
卫生部脑死亡判定标准起草小组. 脑死亡判定标准( 成人)和脑死亡判定技术规范( 征求意见稿) [J]. 中华医学杂志,2003, 83(3):262-264.
|
2. |
陈忠华, 张苏明, 卜碧涛, 等. 脑死亡判定与实践一例 [J].中华医学杂志, 2003, 83(19):1723-1724.
|
3. |
林苗苗, 田克敏. 浅谈脑死亡及其立法问题 [J]. 理论前沿,2007, 13(6):42-43.
|
4. |
中华医学会器官移植学分会. 中国心脏死亡器官捐献工作指南 [J]. 中华器官移植杂志, 2010, 31(7):436-437.
|
5. |
张海波, 孟旭. 心脏移植脑死亡供体的选择标准与管理 [J].心肺血管病杂志, 2008, 27(4):253-256.
|
6. |
Murthy CTVSP. Organ donation:Intensive care issues in managing brain dead [J]. MJAFI, 2009, 65(2):155-160.
|
7. |
陈忠华. 25 年磨一见( 剑) —— 环球性器官短缺与移植危机中的中国新( 心) 路历程 [J/CD]. 中华器移植杂志( 电子版),2010, 4(4):265-272.
|
8. |
Novitzky D, Wicomb WN, Rose AG, et al. Pathophysiology of pulmonary edema following experimental brain death in the chacma baboon [J]. Ann Thorac Surg, 1987, 43(3):288-294.
|
9. |
Schnuelle P, Yard BA, Braun C, et al. Impact of donor dopamine on immediate graft function after kidney transplantation [J].Am J Transplant, 2004, 4(3):419-426.
|
10. |
Salim A, Vassiliu P, Velmahos GC, et al. The role of thyroid hormone administration in potential organ donors [J]. Arch Surg, 2001, 136(12):1377-1380.
|
11. |
Katz K, Lawler J, Wax J, et al. Vasopressin pressor effects in critically ill children during evaluation for brain death and organ recovery [J]. Resuscitation, 2000, 47(1):33-40.
|
12. |
罗爱林, Laekner FX, 田玉科, 等. 芬太尼抑制脑死亡供体器官摘除期间儿茶酚胺和心血管反应 [J]. 临床麻醉学杂志,2000, 16(10):500-502.
|
13. |
王光策, 王锁刚, 张翥, 等. 脑死亡器官捐献移植过程中的问题 [J]. 中国组织工程研究与临床康复, 2011, 15(18):3280-3283.
|
14. |
陈良万, 陈道中, 戴炳光, 等. 脑死亡无偿器官捐献心脏移植二例 [J]. 中国心血管病研究, 2008, 6(2):90-92.
|
15. |
Celb AW, Robertson KM. Anaesthetic management of the brain dead for organ donation [J]. Can J Anaesth, 1990, 37(7):806-812.
|
16. |
吴蓓, 龙村. 体外循环技术在移植器官保护中的应用 [J]. 中国体外循环杂志, 2011, 9(1):60-63.
|
- 1. 卫生部脑死亡判定标准起草小组. 脑死亡判定标准( 成人)和脑死亡判定技术规范( 征求意见稿) [J]. 中华医学杂志,2003, 83(3):262-264.
- 2. 陈忠华, 张苏明, 卜碧涛, 等. 脑死亡判定与实践一例 [J].中华医学杂志, 2003, 83(19):1723-1724.
- 3. 林苗苗, 田克敏. 浅谈脑死亡及其立法问题 [J]. 理论前沿,2007, 13(6):42-43.
- 4. 中华医学会器官移植学分会. 中国心脏死亡器官捐献工作指南 [J]. 中华器官移植杂志, 2010, 31(7):436-437.
- 5. 张海波, 孟旭. 心脏移植脑死亡供体的选择标准与管理 [J].心肺血管病杂志, 2008, 27(4):253-256.
- 6. Murthy CTVSP. Organ donation:Intensive care issues in managing brain dead [J]. MJAFI, 2009, 65(2):155-160.
- 7. 陈忠华. 25 年磨一见( 剑) —— 环球性器官短缺与移植危机中的中国新( 心) 路历程 [J/CD]. 中华器移植杂志( 电子版),2010, 4(4):265-272.
- 8. Novitzky D, Wicomb WN, Rose AG, et al. Pathophysiology of pulmonary edema following experimental brain death in the chacma baboon [J]. Ann Thorac Surg, 1987, 43(3):288-294.
- 9. Schnuelle P, Yard BA, Braun C, et al. Impact of donor dopamine on immediate graft function after kidney transplantation [J].Am J Transplant, 2004, 4(3):419-426.
- 10. Salim A, Vassiliu P, Velmahos GC, et al. The role of thyroid hormone administration in potential organ donors [J]. Arch Surg, 2001, 136(12):1377-1380.
- 11. Katz K, Lawler J, Wax J, et al. Vasopressin pressor effects in critically ill children during evaluation for brain death and organ recovery [J]. Resuscitation, 2000, 47(1):33-40.
- 12. 罗爱林, Laekner FX, 田玉科, 等. 芬太尼抑制脑死亡供体器官摘除期间儿茶酚胺和心血管反应 [J]. 临床麻醉学杂志,2000, 16(10):500-502.
- 13. 王光策, 王锁刚, 张翥, 等. 脑死亡器官捐献移植过程中的问题 [J]. 中国组织工程研究与临床康复, 2011, 15(18):3280-3283.
- 14. 陈良万, 陈道中, 戴炳光, 等. 脑死亡无偿器官捐献心脏移植二例 [J]. 中国心血管病研究, 2008, 6(2):90-92.
- 15. Celb AW, Robertson KM. Anaesthetic management of the brain dead for organ donation [J]. Can J Anaesth, 1990, 37(7):806-812.
- 16. 吴蓓, 龙村. 体外循环技术在移植器官保护中的应用 [J]. 中国体外循环杂志, 2011, 9(1):60-63.