【Abstract】ObjectiveTo evaluate the localized biopsy of nonpalpable breast lesions (NPBLs) and its role in the early diagnosis and treatment of breast cancer.
MethodsOne hundred and fifty-eight NPBLs from a series of 141 women detected by mammography were resected with wire localization technique.
ResultsForty-two lesions (26.6%, 42/158) in 42 patients were diagnosed with malignant result, including 12(28.6%) patients with stage 0 breast cancer, 24(57.1%) with stageⅠ, 2(4.8%) with stage Ⅱ and 4(9.5%) with stage Ⅲ disease according to American Joint Committee on Cancer (AJCC) staging system（the 6th edition）. The contralateral axillary lymph nodes metastasis were found in only one (2.4%) patient with stage Ⅲ disease and the other fortyone patients remained free of recurrent disease at a median follow-up of 31 months.
ConclusionThe results showed that the most nonpalpable breast cancers detected by mammography were earlystage breast cancers and had good prognosis. The NPBLs should get a localized biopsy in order to facilitate the early diagnosis and treatment of nonpalpable breast cancers.
Citation：
WANG Zhongzhao,ZHANG Baoning.. Localized Biopsy of Nonpalpable Breast Lesions and It’s Role in Early Diagnosis and Treatment of Breast Cancer. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2005, 12(3): 223-225. doi:
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- 1. Thor A. A revised staging system for breast cancer [Ｊ]. Breast J， 2004; 10 Suppl 1∶S15.
- 2. AlSobhi SS, Helvie MA, Pass HA, et al. Extent of lumpectomy for breast cancer after diagnosis by stereotactic core versus wire localization biopsy [Ｊ]. Ann Surg Oncol, 1999; 6(4)∶330.
- 3. Sakorafas GH, Farley DR. Optimal management of ductal carcinoma in situ of the breast [Ｊ]. Surg Oncol, 2003; 12(4)∶221.
- 4. Ernster VL, Barclay J, Kerlikowske K, et al. Mortality among women with ductal carcinoma in situ of the breast in the populationbased surveillance, epidemiology and end results program [Ｊ]. Arch Intern Med, 2000; 160(7)∶953.
- 5. Adamovich TL, Simmons RM. Ductal carcinoma in situ with microinvasion [Ｊ]. Am J Surg, 2003; 186(2)∶112.
- 6. Skinner KA, Silberman H, Sposto R, et al. Palpable breast cancers are inherently different from nonpalpable breast cancers [Ｊ]. Ann Surg Oncol, 2001; 8(9)∶705.
