• Department of General Surgery, Military General Hospital of Tibet, Lasha 850003;
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Objective  To evaluate the role of interleukin-10 (IL-10) in acute pancreatitis.
Methods  Thirty mongrel dogs were divided into three groups based on the severity: acute edematous pancreatitis (AEP) group (n=11), acute hemorrhagic necrotizing pancreatitis (AHNP) group (n=12), and control group (n=7). Serum level of IL-10 was determined with enzyme-linked immuno-sorbent assay (ELISA).
Results  Within 24 hours, AEP group had serum level of IL-10 significantly higher than that of AHNP group. Control group had no detectable serum IL-10. No significant difference was observed between AEP group and AHNP group at 48 hours.
Conclusion  The finding of low values of serum IL-10 suggests that there may be more consumption in AHNP group than in AEP group and it may be beneficial to decrease the severity of experimental acute pancreatitis.

Citation: WANG Maox,ZHANG Shengtian,LIU Xiaoli,et al.. INTERLEUKIN-10 IN ACUTE PANCREATITIS. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2000, 7(5): 293-294. doi: Copy

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