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find Keyword "二尖瓣" 251 results
  • 风湿性心脏病二尖瓣和主动脉瓣胶原变化的研究

    摘要 目的 研究风湿性心脏病二尖瓣和主动脉瓣瓣膜胶原含量及其类型对瓣膜成形术病例选择的影响。方法 采用羟脯氨酸法测定瓣膜胶原含量的变化,并用十二烷基磺酸钠-聚丙烯酰胺凝胶电泳(SDS-PAGE)分离法测定心瓣膜胶原的类型。结果 正常二尖瓣腱索的胶原含量较瓣叶高(Plt;0.01),主动脉瓣胶原含量较二尖瓣低(P<0.01)。风湿性心脏病患者二尖瓣和主动脉瓣的胶原含量较正常瓣膜有显著升高(P<0.01)。正常瓣膜以Ⅰ型胶原为主,Ⅲ型胶原含量较少,而病变二尖瓣和主动脉瓣其Ⅰ型、Ⅲ型胶原均明显增加,且以Ⅰ型胶原为主。有钙化的二尖瓣腱索胶原含量高于无钙化瓣膜(P<0.05)。二尖瓣病变以狭窄为主的病例其二尖瓣腱索的胶原含量较以关闭不全为主的病例高(P<0.01),且二尖瓣瓣叶及腱索的胶原含量与二尖瓣口面积呈负相关(r=-0.5431和r=-0.8819,P<0.01)。结论 风湿性心脏病心瓣膜胶原含量和类型的变化与心瓣膜功能的改变密切相关,瓣膜有无钙化以及二尖瓣病变的性质,可作为施行心瓣膜成形术的选择条件。

    Release date:2016-08-30 06:33 Export PDF Favorites Scan
  • Complications after transcatheter mitral valve replacement

    Mitral regurgitation is the most common cardiac valve disease, with high rates of morbidity and mortality. Transcatheter mitral valve replacement (TMVR) is used as a promising intervention in non-surgical patients and in those with unsuitable anatomy for transcatheter edge-to-edge repair. TMVR can also be performed for inoperable or high-risk patients with degenerated or failed bioporstheses or failed repairs, or in patients with severe annular calcifications. The complex anatomy of the mitral valves makes the design of transcatheter mitral valve prostheses extremely challenging, and increases the difficulty of TMVR procedure, thus could led to non-negligible complications including periprocedural and post-procedural long-term complications. This review aims to discuss the potential TMVR-complications and measures implemented to mitigate these complications, in order to improve the prognosis of TMVR patients.

    Release date:2024-10-25 01:48 Export PDF Favorites Scan
  • 经房间隔经导管二尖瓣置换术的手术配合及护理三例

    Release date:2023-09-28 02:17 Export PDF Favorites Scan
  • Progress and prospect of robotic cardiac surgery

    Minimally invasive cardiac surgeries are the trend in the future. Among them, robotic cardiac surgery is the latest iteration with several key-hole incision, 3-dimentional visualization, and articulated instrumentation of 7 degree of ergonomic freedom for those complex procedures in the heart. In particular, robotic mitral valve surgery, as well as coronary artery bypass grafting, has evolved over the last decade and become the preferred method at certain specialized centers worldwide because of excellent results. Other cardiac procedures are in various stages of evolution. Stepwise innovation of robotic technology will continue to make robotic operations simpler, more efficient, and less invasive, which will encourage more surgeons to take up this technology and extend the benefits of robotic surgery to a larger patient population.

    Release date:2019-09-18 03:45 Export PDF Favorites Scan
  • Mitral valve management in hypertrophic obstructive cardiomyopathy and its controversies

    Hypertrophic obstructive cardiomyopathy (HOCM) is a relatively common hereditary cardiomyopathy, which is featured by asymmetric myocardial hypertrophy and dynamic left ventricular outflow tract (LVOT) obstruction. Other than septal hypertrophy, mitral valve abnormalities are also quite common in HOCM patients, and they also contribute to systolic anterior motion of the mitral leaflets and LVOT obstruction. Septal myectomy is believed as the standard surgical treatment for HOCM, but whether to perform mitral valve procedures at the same time of myectomy is still debatable. In this article, we thoroughly explained the mitral valve abnormalities in HOCM patients and their surgical corrections. Besides, we also explained the controversies over mitral valve procedures based on the current clinical studies.

    Release date:2024-08-02 10:43 Export PDF Favorites Scan
  • Clinical Analysis of Mitral Valve Repair for Patients with Mitral Regurgitation

    ObjectiveTo evaluate the effectiveness of mitral valve repair for mitral regurgitation. MethodsWe retrospectively analyzed the clinical data of 47 patients underwent mitral repair in General Hospital of Ningxia Medical University between January 2010 and June 2014 year. There were 36 males and 11 females with age of 10 months to 65 years, mean age of 42.38±15.27 years. ResultsThere was no operative death within follow-up time of 18±7 months (ranged 14 to 1 586 days). Mitral valve function was normal or traces regurgitation in 33 patients (70.21%). Mild mitral regurgitation occurred in 11 patients (23.40%). Postoperative transesophageal echocardiography showed that 2 patients (4.26%) had moderate regurgitation. They underwent mitral valve repair again and cured. One patient (2.13%) underwent mitral valve replacement because of moderate to severe regurgitation. The dimensions of left atrium and left ventricle obviously decreased and heart function improved significantly compared with preoperative ones. ConclusionStrict control of surgical indications for different valve disease, the use of mitral valve repair technique, mitral surgery can get a good clinical efficacy. Preoperative diagnosis by transesophageal echocardiography, intraoperative monitoring, and immediate postoperative assessment for mitral valve repair results provide good technical support.

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  • 二尖瓣成形术治疗二尖瓣反流89例临床分析

    目的 总结二尖瓣成形术治疗二尖瓣反流患者的临床经验,分析其疗效。 方法 回顾性分析2007 年1 月至 2011 年 7月中国医科大学附属第一医院采用二尖瓣成形术治疗89 例二尖瓣中重度反流患者的临床资料,其中男 51例,女 38 例;年龄21~64 (48.6±13.6)岁;病程1周~21 年。术前经食管超声心动图及术中探查发现二尖瓣中度反流(Ⅲ级) 40 例,重度反流 (Ⅳ级) 49 例。56例二尖瓣脱垂,脱垂病变累及A2区4例、A3区5例、P2区25例、P3区14例,累及多处8例;其中二尖瓣腱索断裂37例,腱索冗长脱垂19例;瓣环扩大42例。手术方式:前叶腱索转移4 例 , 前叶人工腱索 6 例 ,前叶裂缝合2例,交界部缝合 6 例 ,后叶矩形切除加 Sliding (滑行) 技术43 例,后叶折叠缝合成形14例,后叶人工腱索12例,缘对缘成形 10 例和心包补片修补瓣叶穿孔 1 例,其中2种以上修复方式9例。全部患者均使用成形环加固瓣环。手术中应用注水试验和食管超声心动图检查评价成形效果。 结果 无围术期死亡。术后心脏超声心动图提示:二尖瓣无反流 (0 级)15 例,微量反流 (Ⅰ级)41 例,轻度反流 (Ⅱ级) 23 例,轻至中度反流 (Ⅲ级)10 例。所有患者均无二尖瓣狭窄。术后随访77例(86.52%),随访时间3~58 (12.3±18.7) 个月。随访期间1例死于脑血管意外;1例行二尖瓣置换术。 结论 综合运用多种二尖瓣成形技术治疗二尖瓣中重度反流,可获得良好的临床疗效。

    Release date:2016-08-30 05:51 Export PDF Favorites Scan
  • 国产二尖瓣成形环在心瓣膜成形外科中的应用

    目的 评价国产二尖瓣成形环在心瓣膜成形外科中的疗效.方法 回顾1986年12月~1995年9月在全身麻醉中度低温体外循环下用国产二尖瓣成形环行成形术36例,其中二尖瓣成形28例次,三尖瓣成形9例次.结果 住院死亡4例.术后发生低心排血量综合征5例,呼吸功能不全2例,行气管切开1例,突发心室颤动3例,多器官功能衰竭2例,脑栓塞1例.随访31例无死亡.经超声心动图检查32个成形瓣膜,未见反流5例,轻度反流23例,中度以上反流2例,轻度狭窄2例.跨瓣压差<1.07kPa(8mmHg)24例,1.07~1.73kPa(8~13mmHg)8例.结论 国产二尖瓣成形环在心瓣膜成形外科中具有重要地位.

    Release date:2016-08-30 06:35 Export PDF Favorites Scan
  • 二尖瓣再狭窄人工瓣膜置换术

    目的 总结 57例左径二尖瓣闭式扩张术后再狭窄的患者经右前外侧切口行二尖瓣置换术的经验。方法 经右前外侧切口第 4肋间进胸,在膈神经前方1.5 cm处纵行切开心包,主动脉阻断期间用顺行性灌注或逆行性灌注氧合血,同时向心腔内注入冰水降低心肌温度的方法保护心肌,行二尖瓣人工瓣膜置换术。结果 本组发生低心排血量综合征4例,手术死亡3例。全组术后呼吸机辅助时间及胸腔引流量与同期经胸正中切口行首次二尖瓣置换术患者比较差别无显著性意义(P>0.05)。结论 左径二尖瓣闭式扩张术后再狭窄的患者经右前外侧切口行二尖瓣置换术能减少心脏与大血管撕裂出血,手术显露好,结合术中良好的心肌保护,可获得较满意的手术疗效。

    Release date:2016-08-30 06:34 Export PDF Favorites Scan
  • 乳头肌瓣环固定技术在二尖瓣置换术中的应用

    目的 分析乳头肌瓣环再固定(papillary muscle repositioning,PMR)技术在二尖瓣置换术中应用的可行性。 方法 回顾性分析 2016 年 3 月至 2017 年 3 月,以二尖瓣病变为主并实施 PMR 技术的瓣膜置换术(均置换的机械瓣膜) 19 例患者的临床资料,其中男 10 例、女 9 例,年龄(52.46±11.22)岁。分析其心功能改善情况及左心室形态等手术效果。 结果 患者围手术期死亡 0 例;开胸止血 1 例,低心排血量综合征(低心排)1 例,强心利尿后好转,并顺利出院。术后仅 1 例出现大量血管活性药物的应用。心脏超声随访结果显示术后 6 个月左心室射血分数(LVEF)均较术前改善,出院前较术前降低;左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)较术前减小,差异具有统计学意义(P<0.05)。 结论 实施 PMR 技术的二尖瓣置换术在维持左心室乳头肌-二尖瓣环的张力和完整性,改善左室容积、左室形态和射血分数方面效果良好。

    Release date:2018-08-28 02:21 Export PDF Favorites Scan
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