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find Author "刘晓雪" 26 results
  • 包皮环切术后阴茎皮肤缺失的修复

    目的 总结包皮环切术后阴茎皮肤缺失的修复方法及临床效果。 方法 2004 年10 月- 2007 年8 月,收治5 例包皮环切术后阴茎皮肤坏死及缺失患者;年龄21 ~ 54 岁。YAG 激光刀操作不当2 例,包皮切除过多、术后感染致局部皮肤广泛坏死、局部麻醉药中加入肾上腺素致局部皮肤坏死各1 例。皮肤缺失范围5 cm × 2 cm ~ 15 cm ×12 cm。除1 例采用厚中厚皮行网状植皮术外,余4 例采用3 cm × 3 cm ~ 10 cm × 3 cm 的阴囊皮瓣修复。供区直接缝合。 结 果 1 例术后2 d 出现尿瘘伴局部皮瓣断层坏死,经换药后自行愈合;断蒂后皮瓣成活良好。其余4 例皮瓣(片)成活良好。供区Ⅰ期愈合。术后5 例均获随访,随访时间3 ~ 12 个月。阴茎外形较满意,采用阴囊皮瓣修复者效果优于皮片。1 例因尿瘘及阴茎皮瓣臃肿需再次手术修复。 结论 包皮环切术应严格掌握适应证,由经验丰富的专科医师施行;术后阴茎皮肤缺失首选阴囊皮瓣修复

    Release date:2016-09-01 09:19 Export PDF Favorites Scan
  • 浅谈手烧伤修复中的一些问题

    1991年以来,收治42例手部烧伤畸形病人,大部分为治疗不当所致。为了提高手部烧伤治疗的效果,提出应普及手外科治疗基本知识,加强医生队伍及手外科专科建设,重视手损伤的早期清创与修复术,正确的包扎固定及早期、持久的康复治疗等。

    Release date:2016-09-01 11:12 Export PDF Favorites Scan
  • 隆乳术后乳房硬化12例

    Release date:2016-09-01 11:14 Export PDF Favorites Scan
  • THE EFFECT OF HEPARIN ON WOUND HEALING OF SECOND-DEGREE BURNED RATS

    OBJECTIVE: To study the effect of therapeutic effect of heparin on wound healing of second-degree burned rats. METHODS: Deep second-degree burns with 20% of total body surface were made in 20 rats, which were randomly divided into 2 groups. The experimental group was treated subcutaneously injection with 1 ml of heparin 100 U/kg and saline solution, and the control group was treated with 1 ml of saline solution, once a day until complete healing of the burned wound. The healing time were compared, the growth of granulation tissue and collagen fibers were evaluated under light microscope, and the growth of fibroblasts were observed under electronic microscope. RESULTS: All rats survived, the healing time of experimental group (22.8 +/- 1.87 days) were much shorter than that of control group (26.2 +/- 2.82 days) (P lt; 0.005). Light microscope observation showed that the growth of granulation tissue and collagen fibers of experimental group were much better than that of control group, and electronic microscope also showed that the fibroblast growth was obviously better in the experimental group. CONCLUSION: Subcutaneous injection of heparin can promote wound healing.

    Release date:2016-09-01 10:27 Export PDF Favorites Scan
  • 隆乳术后并发泌乳八例

    Release date:2016-09-01 11:05 Export PDF Favorites Scan
  • EFFECTS OF NANDROLONE PHENYLPROPIONATE ON THE EXPRESSION LEVEL OF PROα1(Ⅰ) COLLAGEN AFTER BURN IN RATS

    OBJECTIVE: To explore the effects of nandrolone phenylpropionate (NP) on the expression level of pro alpha 1 (I) collagen after burn in rats and the possible mechanism involved in the process. METHODS: Thirty-two Wistar rats with a deep second-degree scald injury and 20% of total body surface area were randomly divided into two groups to receive either 5 mg/kg NP(NP group) or normal saline (control group) every other day. We analyzed the mean integrated optical density(mIOD) of androgen receptor (AR) to determine the distribution and expression of AR in fibroblasts by immunohistochemistry, and measured expression level of pro alpha 1 (I) collagen mRNA by quantitative fluorescent RT-PCR to find the relation between expressions of AR and pro alpha 1 (I) collagen mRNA. The total specimens were obtained from the scalded rats after 4, 7, 14 and 21 of after burn. RESULTS: The expression of pro alpha 1 (I) collagen mRNA in NP group was significantly higher than that in control group on the 7th, 14th and 21st days(P lt; 0.05), but there was no significant difference on the 4th day. The density of AR in fibroblasts had significant difference (P lt; 0.05) between the two groups after 4, 7, 14 and 21 days. A positive relationship existed between the expression of pro alpha 1 (I) collagen mRNA and quantity of AR in fibroblasts(r = 0.836). CONCLUSION: The nandrolone phenylpropionate increased the expression of pro alpha 1 (I) collagen mRNA and enhanced the density of AR in fibroblasts. The higher expression of pro alpha 1 (I) collagen mRNA had a relation with the change of quantity of AR in fibroblasts.

    Release date:2016-09-01 09:35 Export PDF Favorites Scan
  • REPAIR OF CHRONIC OSTEOMYELITIS OF STERNUM AFTER THORACOTOMY WITH GREATER PECTORAL MUSCLE FLAP

    Objective To explore a surgical method for chronic osteomyel itis of sternum after thoracotomy. Methods From January 2006 to February 2009, 11 cases of chronic osteomyelitis after thoracotomy (2 cases of coronary bypass, 6 cases of mitral valve replacement, and 3 cases of ventricular defect repair) were admitted. Of them, there were 6 males and 5females, aged from 6 to 62 years (median 34 years), including 6 cases of simple osteomyelitis of sternum, 2 cases of osteomyelitis of sternum with suppurative infection of mediastinum, and 3 cases osteomyel itis of sternum with costal chondritis. Necrotic sternum were excised and defect was from 4 cm × 3 cm to 7 cm × 4 cm. Greater pectoral muscle flap was designed from 8 cm × 5 cm to 10 cm × 6 cm on one side and was transferred to defect. Negative drainage and sensitive antibiotics were administered after operation. Results Healing by first intention was achieved in 10 patients except 1 patient who had a few discharge at the drainage outlet and whose incision healed 1 week later. The follow up was from 3 to 10 months with an average of 6 months. The formed scars were flat with soft texture in 8 patients and moderately hypertrophy in 3 patients. The wounds healed without pain, relapse or abnormal function of donor upper limb. Conclusion Transplantation of greater pectoral muscle flap is an effective way to repair chronic osteomyelitis of sternum after thoracotomy.

    Release date:2016-08-31 05:47 Export PDF Favorites Scan
  • SYNTHETIC THERAPY FOR KELOID IN AURAL REGION

    【Abstract】 Objective To summarize the effectiveness of surgical removal combined with adjuvant therapy onthe aural region keloid. Methods From January 2000 to December 2005, 42 patients (71 side ears) with keloid at the auralregion were treated. There were 8 males and 34 females, aged 16 to 50 years (mean 26.2 years). The course of diseaseranged from 6 months to 4 years. The causes of disease included earhole piercing (n=32), ear trauma(n=7), and postoperativehyperplasia(n=3); the sizes of keloids ranged from 0.3 cm × 0.3 cm× 0.2 cm to 6.0 cm × 4.0 cm × 1.0 cm with globular, dumb-bell,nodular shapes. According to the different sizes and the range of keloids, different operations to remove the keloids and repairthe defect tissue were chosen. Wounds were exposed to the electron beam at first 24 hours after operation, once a day at 2 Gyeach time for 10 days. An immediate local injection for the keloid with hormones anti-scar drugs, which was a mixture of Betamethasone(Diprospan) and 2% Lidocaine with a proportion of 1 ∶ 3, was given to the patients who had recurrence trend 3 times,every 3 weeks. Results After operation, all the wounds healed by first intention. And 37 cases(64 lateral ears) were followedup for 1 year, and all achieved cl inical cure. Five cases (7 lateral ears) had the trend of recurrence 3-6 months after operation andwere cured after the immediate local injection for the keloid with hormones anti-scar drugs. According to LIU Wenge’s curativecriterion, 37cases were cured and 5 cases responded to treatment. Conclusion Surgical removal combined with local radiationand hormones infiltrated individually as early as possible can effectively treat aural region keloids. And it is an optimal method.

    Release date:2016-09-01 09:09 Export PDF Favorites Scan
  • 带蒂皮瓣修复手部热压伤18例

    Release date:2016-09-01 11:07 Export PDF Favorites Scan
  • 腰背部巨型先天性黑色素痣一例报告

    目的总结1例腰背部巨型先天性黑色素痣(简称巨痣)的特点、治疗方法及疗效。 方法2013年7月收治1例13岁腰背部巨痣女性患儿,入院检查示黑斑上至第12肋平面,下至臀部上份,两侧达腋前线;表面无毛发,凹凸不平,颜色不均匀,质地偏硬。全麻下行腰背部巨痣切除联合右侧臀大肌肌瓣(12 cm×8 cm大小)、自体上背部网状刃厚皮片(59 cm×47 cm大小)修复术,术中见巨痣浸润深度达髂骨骨膜,浸润宽度在真皮及以下,超出术前判定范围。 结果术后综合病理检查确诊为巨痣,累及皮下组织,有坏死,部分细胞增生活跃。术后20 d创面愈合。术后6个月(2014年1月)随访,创面部分瘢痕形成,未见复发病灶。 结论巨痣浸润可深达骨膜,其皮下浸润范围可能超出肉眼所见;因有恶变风险,宜采取手术扩大切除。

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