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find Author "徐志伟" 46 results
  • Bloodless Surgery and Its Application in Cardiac Surgery

    Bloodless surgery is a comprehensive and systematic perioperative treatment approach in order to avoid allogeneic transfusion for surgery,improve patient prognosis,and relieve blood shortage. Bloodless heart surgery indicates some perioperative strategies to avoid allogeneic transfusion and improve clinical outcomes,which involves participation of cardiac surgeons and other professionals during cardiac surgery. For years,many cardiac surgeons have utilized several blood management and conservation techniques during open heart surgery to avoid allogeneic transfusion. Research results from major medical centers indicate that bloodless heart surgery can shorten postoperative recovery period and improve patientprognosis. In this review,we describe basic theory and systematic methods of bloodless surgery,and summarize applicationprogress of bloodless heart surgery and current status in China.

    Release date:2016-08-30 05:47 Export PDF Favorites Scan
  • Surgical Treatment of Complete Transposition of Great Arteries with Ventricular Septal Defect and Pulmonary Stenosis

    Surgical treatment of complete transposition of great arteries with ventricular septal defect and pulmonary stenosis (TGA/VSD,PS) consists of Rastelli procedure, Lecompte procedure, Nikaidoh procedure, Yamagishi procedure and Ross-Konno switch procedure. Rastelli procedure and Lecompte procedure cause less myocardial lesion but more late complications. Nikaidoh procedure and Yamagishi procedure achieve better anatomical repair but involve more myocardial lesion. Ross-Konno switch procedure has a narrow surgical indication. So for patients with TGA/VSD,PS, different surgical methods should be used according to surgical indications and individual conditions. In this paper, the advantages and disadvantages, indication, contraindication, outcome and prospect of them are reviewed.

    Release date:2016-08-30 06:16 Export PDF Favorites Scan
  • Classification and Surgical Management of Coronary Arterial Anomalies in Complete Transposition of the Great Arteries

    Abstract: The complete transposition of the great arteries (TGA) is one of the commonest congenital cardiac anomalies in cyanosis. In untreated patients, death occurs early in infancy. Nowadays arterial switch operation (ASO) has been widely proposed to treat TGA without pulmonary valve stenosis. Meanwhile, surgical risks and mortality will be increased if TGA is accompanied by coronary arterial anomalies. So proper surgical management of abnormal coronary artery has a significant influence on the outcome of ASO. The classification, operation methods and surgical results were reviewed in this article.

    Release date:2016-08-30 06:08 Export PDF Favorites Scan
  • Repair of Truncus Arteriosus: Choice of Right Ventricle Outflow Tract Reconstruction

    Corresponding author: XU Zhi-wei, E-mail: zwxumd@online.sh.cn Abstract: Objective To compare the two different ways of right ventricle  pulmonary artery (RV-PA) reconstruction at repair of persistent truncus arteriosus(PTA), the direct RV-PA anastomosis and extra conduit connection, in order to find the better way. Methods From Feb. 2000 to Sept. 2006, 23 patients had undergone the repairs of truncus arteriosus in our hospital, age at operation from 1.5 to 63.3 months. Patients were divided into 2 groups according to the way of RV  PA reconstruction. Group Ⅰ : 18 of them, using direct RV-PA anastomosis, group Ⅱ : 5 of them, using valved homograft or Gore-Tex conduit. 3 patients were associated with interrupted aortic arch (IAA). Kaplan-Meier was used to calculate postoperative mortality, survival time and re-operation situation. Paired t-test and group t-test were used to evaluate late pulmonary growth and cardiac function.Results There were 2 early hospital death, there were 17 patients in follow-up for 2.14 ± 1.97y (32.00d-6.95y). No later death during follow-up. Total survival rateo was 91.30%(21/23), 95% CI of survival time was 5.55-7.15y. Survival ratio of group Ⅰ was 94.40%, and that of group Ⅱ was 80%. One patient had undergone re  operation for right ventricular outflow tract obstruction (RVOTO). The difference between the diameter of postoperative RV-PA anastomosis was statistically significant. The early diameter of group Ⅰ was 1.01 ± 0.26cm, later was 1.32 ± 0.45cm(P=0.019). The velocity of flow at the position of anastomosis and the peristome of right pulmonary artery (RPA)/left pulmonary artery (LPA) was acceptable. Compared the postoperative cardiac function, late left ventricle ejection fraction (LVEF) really improved with a significant difference [ group Ⅰ , early was 62.82%, late was 69.87%(P=0.026); group Ⅱ , early was 58.17%, late was 64.00%(P=0.029) ] . No re-operation for truncal valve regurgitation was needed. Conclusions The postoperative survival and follow-up results are satisfactory. A direct anastomosis of RV-PA continuity has the potential for right ventricle outflow tract (RVOT) growth and associated with low rate of pulmonary artery and bifurcation obstruction. The heart function is really improved during follow-up. IAA and truncal valve regurgitation are two major risk factors of associated with hospital death.

    Release date:2016-08-30 06:08 Export PDF Favorites Scan
  • 一期手术纠治主肺动脉窗及伴发畸形

    目的 总结一期手术纠治主-肺动脉窗及伴发畸形的临床经验,以提高手术疗效。 方法 我科共收治26例主-肺动脉窗患者,男14例,女12例;年龄1.4±1.6岁;体重7.8±3.8kg。其中单纯主-肺动脉窗8例,合并主动脉弓中断、右肺动脉异常起源于主动脉、法洛四联症、房间隔缺损、室间隔缺损、二尖瓣反流和气管狭窄等18例。25例患者一期手术经主动脉切口补片关闭瘘口纠治主-肺动脉窗,同时纠治伴发的畸形;1例放弃治疗。 结果 全组无手术死亡。2例伴主动脉弓中断、动脉导管未闭和右肺动脉起源于升主动脉的新生儿术后3d延迟关胸;1例术后出血,3h后再次开胸止血。术后随访22例,随访时间1个月~4年。所有患者无明显的主动脉瓣上狭窄和肺动脉分支狭窄,2例残留轻度二尖瓣反流,1例残留轻至中度二尖瓣反流。 结论 主-肺动脉窗患者早期易发生肺动脉高压,一经诊断应立即手术。手术方式首选修补主肺动脉窗及一期纠治伴发畸形。尽管主-肺动脉窗可合并各种心内外畸形,但早期手术纠治可获得较好的中长期疗效。

    Release date:2016-08-30 06:09 Export PDF Favorites Scan
  • 功能性单心室的外科治疗

    目的 为了使更多的先天性心脏病患者得到纠治,回顾性总结手术治疗功能性单心室的临床经验.方法 手术纠治127例功能性单心室患者,年龄7个月~12岁,体重7.5~39 kg,其中丰唐手术(Fontan operation)72例,半Fontan术3例,双向上腔静脉肺动脉吻合术51例,肺动脉环缩术1例. 结果 早期Fontan术19例,死亡11例;改良Fontan术 53例,死亡10例;半Fontan术死亡1例 ;双向上腔静脉肺动脉吻合术死亡4例;总手术死亡率20.5%. 结论 功能性单心室必须早期得到纠治,控制肺动脉血流,预防严重缺氧.双向上腔静脉肺动脉吻合术能减少功能性单心室的容量负荷,保持足够的心排血量.改良Fontan术是功能性单心室的最佳手术方案.

    Release date:2016-08-30 06:32 Export PDF Favorites Scan
  • Modified Nuss Procedure for Pectus Excavatum on Pediatric Patients

    Objective To summarize the early experience of modified Nuss procedure with thoracoscope for repairing pectus excavatum in children. Methods Fiftythree pediatric pectus excavatum were treated by modified Nuss procedure with thoracoscope from June 2004 to July 2006, theage ranged from 2.4 to 16.0 years, the average age was 8.1 years. Thirtysix patients were symmetric pectus excavatum and 17 patients were asymmetric pectus excavatum. Results The operation in all patients were successful, the average blood loss was less than 10ml. Pericardium perforation occurred in 2 earlier patients during the operation, pneumothorax occurred in 6 patients postoperatively,pleural effusion occurred in 3 patients, and all resolved by corresponding treatments. The average hospital length of stay was 5.5 days. All patients had a satisfied deformity correction and no needs of transfusion. The depression was thoroughly corrected in 48 patients, residual depression was less than 20% of preoperative degrees in 5 patients. Therapeutic results evaluation showed excellent in 46 patients and good in 7 patients. All patients were followed up in 1-25 months without any complaints, the activity ability was same as normal children; there were no bar displacement and injury event occurred. The bar had been removed in 1 patient 24 months after surgery who still kept in excellent results. Conclusion Modified Nuss procedure is easy to be performed with minimal invasion and good shortterm results. Thoracoscopic visualization facilitates the safety of this technique. It is recommendable to be tried and extended applied. 

    Release date:2016-08-30 06:15 Export PDF Favorites Scan
  • L-精氨酸对乳猪深低温停循环脑代谢与结构的影响

    目的 通过深低温停循环(DHCA)转流模型,研究左旋精氨酸(L-arg)在低温缺血时对脑代谢和结构的影响. 方法 采用上海种白猪,3~4周龄,随机均分成4组: L-arg组,左旋硝基精氨酸甲酯(L-NAME)组, L-arg+L-NAME组和对照组,每组10只.按临床方法行心肺转流术,于转流前、降温末、复温末和转流结束等分别测定颈内静脉一氧化氮(NO)、脑皮质三磷酸腺苷(ATP)和颈内静脉乳酸含量.并行脑组织学和超微结构观察. 结果 降温末L-NAME组和对照组NO含量较其它两组明显下降(Plt;0.01).复温末,除L-NAME组外,其余3组均恢复至转流前水平(Plt;0.01),L-arg组NO水平在复温末较转流前高(Plt;0.01). 转流开始后大脑皮质ATP即有明显下降,L-arg组下降幅度最小,且在复温末已接近转流前水平;L-NAME组下降幅度最大(Plt;0.01). 转流开始后颈内静脉乳酸含量即升高,L-arg组和L-arg+L-NAME组上升幅度较小;降温末和转流结束乳酸含量较其它两组低(Plt;0.01). 大脑皮质组织学和超微结构检查显示,大脑皮质细胞结构变化L-arg组和L-arg+L-NAME组较对照组和L-NAME组轻. 结论 深低温停循环手术时,应用L-arg具有较好的脑保护作用,而L-NAME有脑损害作用.L-arg可部分逆转DHCA时L-NAME对脑组织的损害作用.

    Release date:2016-08-30 06:32 Export PDF Favorites Scan
  • Investigation of Risk Factors Influencing the Mortality of the Arterial Switch Operation

    Objective To analyze the outcome of arterial switch operation (ASO) for surgical repair of complete transposition of the great arteries (TGA), and to investigate the risk factors influencing the mortality of ASO. Methods The clinical data of patients suffered from TGA and treated with ASO from the January 2003 to December 2004, and the clinical records in hospital including eehoeardiogram and operation record were collected. The clinical data were analyzed by chi-squared test and logistic muhivariable regression analysis, including the age undergone operation, body weight, diagnosis, anatomic type of coronary artery, cardiopulmonary bypass time, aortic crossclamping time, circulation arrest time, assisted respiration time after operation, the delayed closure of sternum and so on. The risk factors influencing the early mortality of the ASO were analyzed. Results Sixty seven patients were operated with ASO, five patients died during the peri-operative period. The outcome of univariate analysis indicated that risk factors influencing the mortality of ASO included: age(P=0. 004), body weight (P=0. 042), anatomic type of coronary artery (P= 0. 006) and extracorporeal circulation time (P= 0. 048), the length of the CICU stay(P= 0. 004) and the hospital stay(P=0. 007) after operation in the TGA/VSD patients were longer than those in TGA/ IVS patients. The logistic muhivariable regression analysis indicated that the age at operation (P= 0. 012), coronary arteries anomaly (P = 0.001 )and the longer cardiopulmonary bypass time (P = 0. 002) were correlated with the increase of death rate. Conclusion It could be good results for TGA patients who was repaired with ASO. The age at operation, the coronary arteries anomaly and the longer cardiopulmonary bypass time are the risk factors influencing the mortality.

    Release date:2016-08-30 06:22 Export PDF Favorites Scan
  • 单心室的外科治疗

    目的 回顾总结单心室的手术治疗经验。 方法 1973年1月~1999年12月共纠治单心室47例,其中包括右心室型17例,左心室型14例,另16例诊断不明确。手术方式为肺动脉环缩术1例,丰唐手术(Fontan operation)23例,双向上腔静脉肺动脉吻合术23例。 结果 全组死亡7例,死亡率15%;行双向上腔静脉肺动脉吻合术患者中无死亡。 结论 单心室患者早期必须采取手术治疗,防止肺部充血和严重缺氧。双向上腔静脉肺动脉吻合术能改善单心室的压力和容量负荷,降低手术死亡率,减少Fontan手术的危险因素。

    Release date:2016-08-30 06:33 Export PDF Favorites Scan
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