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find Keyword "急性心肌梗死" 44 results
  • Surgical Management of Patients with Acute Myocardial Infarction

    Objective\ To analyze the experiences of emergent or urgent coronary artery bypass grafting(CABG) for patients with acute myocardial infarction(AMI). Methods\ From May, 1996 through December, 1999, 9 patients with AMI underwent emergent CABG including eight males and one female, with mean age 61 years, and year range 44 70. The localization of the AMI was anterior in 4 and inferior in 5. The interval between the onset of AMI and CABG was within 24 hours in 7 cases, 10 days in 1 case and 14 days in 1 case....

    Release date:2016-08-30 06:35 Export PDF Favorites Scan
  • The use of intraoperative transesophageal ultrasound in the assessment of ventricular septal rupture complicated with left ventricular aneurysm after acute myocardial infarction: A case report

    We reported a 65-year-old female who was admitted to our institute with "recurrent subxiphoid pain accompanied by dyspnea for more than 10 days". Electrocardiogram examination suggested acute extensive anterior ST segment elevation myocardial infarction. Preoperative transthoracic echocardiography suggested ventricular septal rupture. The patient was planned for the repair of ventricular septal rupture with cardiopulmonary bypass. The formation of left ventricular aneurysm was diagnosed by intraoperative transesophageal echocardiography (TEE). The surgeon decided to abdopt the modified incision of left ventricular approach guided by TEE, which greatly improved the prognosis of the patient. The surgery duration was 197 min, aortic cross-clamping time was 56 min, cardiopulmonary bypass time was 69 min, and the patient was safely admitted to ICU after the surgery. Extubation was performed on the first day postoperatively, and the intra-aortic balloon pump support was retreated on the second day postoperatively. Postoperative echocardiography showed that no obvious residual shunt was observed after ventricular septal repairment and ventricular aneurysm resection. The patient was discharged on the 12th day after the surgery. Additionally, the mental condition was good and daily activities were not limited within 6 months postoperatively.

    Release date:2022-06-24 01:25 Export PDF Favorites Scan
  • Why Percutaneous Coronary Intervention Can’t Improve the Long-term Outcome of Medicare Patients with Acute Myocardial Infarction in USA?

    Release date:2016-09-07 02:26 Export PDF Favorites Scan
  • 急性心肌梗死合并焦虑抑郁患者的心理干预

    【摘要】 目的 评价心理干预措施在急性心肌梗死治疗中的意义。方法 2008年2月—2009年2月,将50例急性心肌梗死合并焦虑抑郁患者随机分为对照组和观察组,对照组常规治疗,观察组在对照组的基础上联用心理干预措施。对两组患者焦虑自评量表(SAS)、抑郁自评量表(SDS)、满意度等情况进行比较。结果 两组患者负性情绪均有所好转,但治疗后观察组SAS评分为(32.15±6.17)分,明显低于对照组的(46.28±7.35)分(Plt;0.05);观察组SDS评分为(27.59±6.31)分,明显低于对照组的(38.75±5.69)分(Plt;0.05)。出院时观察组总满意率为64%,明显高于对照组的总满意率(36%)(Plt;005)。结论 在采用常规治疗的基础上联用心理干预措施治疗急性心肌梗死合并焦虑抑郁有提高疗效的作用,建议临床进一步推广。

    Release date:2016-09-08 09:37 Export PDF Favorites Scan
  • Research on a diagnostic model for differentiating acute myocardial infarction from unstable angina based on bile acid profile

    Objective To detect the bile acid profile in serum based on liquid chromatography-tandem mass spectrometry, and construct a combined biomarker diagnostic model for differentiating acute myocardial infarction (AMI) from unstable angina (UA). Methods A total of 180 patients with acute coronary syndrome who visited Huludao Central Hospital between August 2023 and February 2024 were randomly selected, and there were 117 patients with UA and 63 patients with AMI. Using liquid chromatography-tandem mass spectrometry, 15 bile acid subtypes in serum were detected. Orthogonal partial least squares discriminant analysis was used to compare the serum bile acid metabolic profiles of the subjects. Differences in metabolites were screened based on a significance level of P<0.05 and variable importance in projection (VIP)>1. Multiple logistic regression analysis was performed to construct a diagnostic model for differentiating AMI from UA, and the diagnostic performance of the model was evaluated using receiver operating characteristic (ROC) curve and other statistical methods. Results The differential bile acid biomarkers in the serum of UA and AMI patients included glycodeoxycholic acid, glycochenodeoxycholic acid (GCDCA), deoxycholic acid (DCA), glycocholic acid, and aurodeoxycholic acid (TDCA) (P<0.05, VIP>1). A binary logistic stepwise regression analysis showed that three bile acid biomarkers (GCDCA, DCA, and TDCA) and three common biochemical indicators (aspartate aminotransferase, creatine kinase, and total bile acid) were factors differentiating AMI from UA (P<0.05). The area under the ROC curve of the model was 0.986 [95% confidence interval (0.973, 0.999), P<0.001], demonstrating a good diagnostic performance. Conclusions GCDCA, DCA, and TDCA can serve as potential biomarkers for distinguishing AMI from UA. The model combining these three bile acids with aspartate aminotransferase, creatine kinase, and total bile acid can effectively identify AMI.

    Release date:2024-10-25 01:48 Export PDF Favorites Scan
  • 急性心肌梗死患者血浆P-选择素水平及临床意义

    【摘要】 目的 探讨急性心肌梗死患者血浆P-选择素(P-selectin,Ps)的含量及其意义。 方法 2009年12月-2010年5月间采用酶联免疫吸附试验分别测定35例冠心病患者、30例急性心肌梗死患者急性期及恢复期两个时期血浆中Ps、血清心肌肌钙蛋白I(cTnI)和肌红蛋白(Myo)含量,与20例健康体检者作对照。 结果 急性心肌梗死急性期与恢复期比较,Ps、cTnI和Myo水平明显上升(Plt;0.05);急性心肌梗死急性期与冠心病组比较也差异统计学意义(Plt;0.05),均高于对照组(Plt;0.05)。急性心肌梗死恢复期与冠心病组比较差异无统计学意义(Pgt;0.05)。 结论 Ps、cTnI和Myo水平升高与急性心肌梗死的进展有关,可作为鉴别诊断急性心肌梗死的指标。

    Release date:2016-09-08 09:26 Export PDF Favorites Scan
  • The Optimal Timing and Operation Pattern of Emergent Coronary Artery Bypass Grafting after Acute Myocardial Infarction

    Objective To summarize the efficacy and clinical experiences of emergent coronary artery bypass grafting (E-CABG) in patients with acute myocardial infarction (AMI) and to discuss the operative opportunity and procedures. Methods We retrospectively analyzed the clinical data of 21 patients with AMI undergoing E-CABG in Sun Yatsen Cardiovascular Disease Hospital between June 1999 and December 2009. Among the patients, there were 14 males and 7 females with their age ranged from 24 to 81 years (63.9±12.4 years). Six patients were operated within 6 hours after the onset of AMI, 7 patients were operated from 6 hours to 3 days after the onset of AMI, and 8 patients were operated from 3 days to 30 days after the onset of AMI. Eight patients had the cardiogenic shock after AMI, one had rupture of ventricular septum and cardiogenic shock, two had rupture of coronary artery after percutaneous transluminal coronary angioplasty, eight had unstable angina and frequent ventricular arrhythmia, one had ventricular fibrillation and cardiac arrest, and one had cardiac trauma. Ten patients were treated with intraaortic balloon pump (IABP). Conventional CABG was performed for 12 patients, off-pump CABG for 5 patients, and on-pump-beating CABG for 4 patients. Results Five patients died after E-CABG with a mortality of 23.8% which was obviously higher than the overall CABG mortality (23.8% vs. 3.1%, χ2=21.184, P<0.05). There were respectively 2, 2 and 1 deaths with a mortality of 33.3%, 28.6% and 12.5% respectively for operations within 6 hours, 6 hours to 3 days and 3 to 30 days after the onset of AMI. The mortality of those patients who were operated within 3 days after AMI was obviously lower (P<0.05). The primary causes of death were low cardiac output syndrome, perioperative acute myocardial infarction after CABG and sapremia. There was one death each for patients operated with off-pump and on-pump-beating CABG. Sixteeen patients were discharged from the hospital. The follow-up was from 6 months to 10 years. There were 6 late deaths among which 5 died of cardiac failure accompanied by pulmonary infection, one died of noncardiac factor. Ten patients survived at present, and the quality of life among 5 patients was unsatisfactory. Conclusion The mortality of E-CABG is obviously higher in patients operated within 3 days of AMI. With the support of IABP, if the operation can be carried out 3 days after the onset of AMI, the surgical success rate will be greatly improved by adopting proper offpump and onpumpbeating procedures.

    Release date:2016-08-30 05:57 Export PDF Favorites Scan
  • Study on the Development of Acute Myocardial Infarction Model in Old Rats

    【摘要】 目的 用老年大鼠建立一种与人类发病年龄相符的稳定可重复的急性心肌梗死动物模型。 方法 Wistar大鼠经戊巴比妥钠麻醉后,气管切开插管,连通呼吸机,开胸后结扎左冠状动脉前降支。分不同时间点测血流动力学后取出心脏行病理组织学观察。 结果 成功建立老年大鼠心肌梗死模型并进行病理组织学验证。 结论 建立老年大鼠心梗模型是可靠的,有助于指导临床实践。【Abstract】 Objective To develop a steady and repeatable acute myocardial infarction model in old rats in accordance to human age. Methods Wistar rats were anaesthetized with sodium phenobarbital. After tracheotomy intubation, respiration machine was linked. Left anterior thoracotomy was performed to ligate the left anterior descending coronary artery. After hemodynamic parameters were obtained at various time points, hearts of the rats were taken for pathologic and histological examinations. Results The model of acute myocardial infarction in old rats was established successfully and proved by pathologic and histological staining. Conclusion It is reliable to establish the myocardial infarction model in old rats, which is helpful in guiding clinical practices.

    Release date:2016-09-08 09:26 Export PDF Favorites Scan
  • 急性心肌梗死室间隔穿孔介入封堵后残余分流致急性左心衰竭一例

    Release date:2020-12-31 03:27 Export PDF Favorites Scan
  • 经导管二尖瓣缘对缘修复术救治急性心肌梗死并发二尖瓣乳头肌断裂一例

    Release date:2022-05-24 03:47 Export PDF Favorites Scan
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