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find Keyword "慢性胰腺炎" 47 results
  • Selection of Surgical Operation in Diagnosis and Treatment for Chronic Pancreatitis

    Release date:2016-09-08 10:24 Export PDF Favorites Scan
  • Chronic Pancreatitis: The Relationship with Pancreatic Cancer and It’s Diagnosis and Treatment

    慢性胰腺炎是一种胰腺的进展性和不可逆性炎症病变,最终将导致胰腺结构破坏和内、外分泌功能的丧失。病程通常呈反复发作性,表现为复发性腹痛或慢性无痛综合征。急性胰腺炎、慢性胰腺炎和胰腺癌这三种疾病之间存在着较复杂的关系。急性胰腺炎的发作通常先于慢性胰腺炎几年时间,而胰腺癌往往是在慢性胰腺炎明确诊断后20年左右发生,关于他们在发病上是否存在着一定的序贯性或是有其他短暂的联系,目前仍有争论。一些资料完整的临床病例随访分析提示,长期患慢性胰腺炎的患者发展为胰腺癌的危险性明显高于普通人群。

    Release date:2016-08-28 04:47 Export PDF Favorites Scan
  • 肝内外胆管结石并发慢性胰腺炎和十二指肠乳头癌1例报告

    Release date:2016-08-29 09:18 Export PDF Favorites Scan
  • The interpretation of the American College of Gastroenterology clinical guideline on chronic pancreatitis and the comparison of related guidelines domestically and abroad

    In February 2020, the American College of Gastroenterology (ACG) published the latest guideline on chronic pancreatitis, and put forward practical recommendations on the etiology, natural history, diagnosis, treatment, prognosis and follow-up of chronic pancreatitis. This paper aims to provide references for the diagnosis and treatment of chronic pancreatitis in China by interpreting the main content of the guideline and comparing it with related guidelines or consensuses domestically and abroad.

    Release date:2020-12-25 01:39 Export PDF Favorites Scan
  • Risk factors for intraoperative massive hemorrhage in patients with pancreatitis-induced sinistral portal hypertension

    ObjectiveTo analyze risk factors of intraoperative massive hemorrhage in patients with pancreatitis-induced sinistral portal hypertension (SPH) and to explore its strategies of treatment.MethodsThe clinical data of patients with pancreatitis-induced SPH admitted to the West China Hospital of Sichuan University from January 2015 to March 2018 were retrospectively analyzed. The intraoperative massive hemorrhage was defined as the blood loss exceeding 30% blood volume. The factors closely associated with the intraoperative massive hemorrhage were analyzed by the forward logistic regression model.ResultsA total of 128 patients with pancreatitis-induced SPH were enrolled in this study, including 104 males and 24 females, with an average age of 47 years old and a median intraoperative bleeding volume of 482 mL. Among them, 93 patients with pancreatitis-induced SPH caused by the pancreatic pseudocyst after acute pancreatitis and 35 caused by the chronic pancreatitis. There were 36 patients with history of upper gastrointestinal bleeding and 46 patients with hypersplenism. Thirty-six patients suffered from the massive hemorrhage. Among them, 30 patients underwent the distal pancreatectomy concomitant with splenectomy, 1 patient underwent the duodenum- preserving resection of pancreatic head, and 5 patients underwent the pseudocyst drainage. The univariate analysis showed that the occurrence of intraoperative massive hemorrhage in the patients with pancreatitis-induced SPH was not associated with the gender, age, body mass index, albumin level, upper gastrointestinal bleeding, hypersplenism, type of pancreatitis, course of pancreatitis, number of attacks of pancreatitis, size of spleen, maximum diameter of lesions in the splenic vein obstruction site, or number of operation (P>0.05), which was associated with the diameter of varicose vein more than 5.0 mm (χ2=19.83, P<0.01), the intraperitoneal varices regions (χ2=13.67, P<0.01), the location of splenic vein obstruction (χ2=5.17, P=0.03), the operation time (t=–3.10, P<0.01), or the splenectomy (χ2=17.46, P<0.01). Further the logistic regression analysis showed that the varicose vein diameter more than 5.0 mm (OR=6.356, P=0.002) and splenectomy (OR=4.297, P=0.005) were the independent risk factors for the intraoperative massive hemorrhage in the patients with pancreatitis-induced SPH.ConclusionsSplenectomy and having a collateral vein more than 5.0 mm in diameter are independent risk factors for intraoperative massive blood loss in surgeries taken on patients with pancreatitis-induced SPH. Attention should be paid to dilation of gastric varices and choice of splenectomy.

    Release date:2019-05-08 05:37 Export PDF Favorites Scan
  • 腹腔镜手术在慢性胰腺炎治疗中的应用

    目的 探讨腹腔镜手术治疗慢性胰腺炎的安全性及可行性。方法 收集2015年1月至2020年12月期间采用腹腔镜手术治疗的21例慢性胰腺炎患者的临床资料,其中胰管结石伴主胰管梗阻10例,胰头部肿块形成7例,胰腺实质明显萎缩4例。 结果 中转开腹3例;手术时间175~430 min(中位数305 min),术中出血量100~800 mL(中位数260 mL)。手术方式包括腹腔镜胰十二指肠切除术8例,腹腔镜胰管切开取石联合空肠吻合术(Partington术)5例,腹腔镜全胰十二指肠切除术4例,腹腔镜改良Beger术2例,腹腔镜胰体尾切除术2例(1例保留脾脏)。术后腹腔引流管拔除时间2~14 d(中位数8 d)。术后出现生化瘘3例,胃排空延迟2例。术后住院时间6~21 d(中位数9 d)。围手术期无死亡病例,无B、C级胰瘘,无非计划再次手术发生。随访12~84个月(中位数36个月),无胰腺恶性肿瘤发生,无脾梗死。结论 腹腔镜手术治疗慢性胰腺炎安全可行。

    Release date:2022-11-24 03:20 Export PDF Favorites Scan
  • Advances in clinical and minimally invasive applications of duodenum-preserving pancreatic head resection

    ObjectiveTo explore the advantages and disadvantages of duodenum-preserving pancreatic head resection (DPPHR) in the clinical application of pancreatic surgical diseases, and to summarize the progress of minimally invasive application of DPPHR combined with the current application of laparoscopy and robot surgery in pancreatic surgery. MethodThe related research literatures about DPPHR at home and abroad in recent years were searched and reviewed. ResultsThe effect of DPPHR compared with traditional pancreaticoduodenectomy (PD) for treatment of benign pancreatic diseases was still controversial, and the postoperative remission effect, perioperative period, occurrence of long-term complications and improvement of quality of life were not very advantageous compared with PD, and the prognosis of minimally invasive surgery was poor. ConclusionDPPHR remains highly controversial for surgical intervention in benign pancreatic disease and has enormous scope for advances in minimally invasive surgical applications in pancreatic surgery, but more clinical studies are needed to verify its clinical efficacy.

    Release date:2023-11-24 10:51 Export PDF Favorites Scan
  • Differentiation of Chronic Mass-Forming Type Pancreatitis from Pancreatic Carcinoma by Functional Magnetic Resonance Imaging

    Objective To summarize the principle and application of functional MR imaging of pancreatic carcinoma and chronic mass-forming type pancreatitis. Methods Articles about diffusion-weighted imaging (DWI), magnetic resonance spectrum imaging (MRSI) and dynamic contrast-enhanced MR imaging of pancreatic carcinoma and chronic pancreatitis were reviewed and analyzed. Results Functional MR imaging could reflected the differences in molecules diffusion, metabolism and tissue perfusion between pancreatic carcinoma and chronic pancreatitis. Conclusion  As a non-invasive protocol, functional MR imaging can provide useful information in differential diagnosis between chronic mass-forming type pancreatitis and pancreatic carcinoma.

    Release date:2016-08-28 04:08 Export PDF Favorites Scan
  • Progress of acute obstructive suppurative pancreatic ductitis in diagnosis and treatment

    Objective To investigate the etiology, pathogenesis, clinical manifestations, diagnosis and treatment of acute obstructive suppurative pancreatic ductitis (AOSPD). Method The literature reports on AOSPD at home and abroad were reviewed and analyzed comprehensively based on clinical experience. Results AOSPD was a rare clinically infectious disease of purulent pancreatic duct. Chronic pancreatitis and ampullary operations were the main pathogenesis factors. The clinical symptoms were non-specific, and the imaging manifestations were pancreatic duct dilatation and pancreatic duct calculi. The clinical diagnosis was mainly determined by epigastrium CT or endoscopic retrograde cholangiopancreatography, which was easy to be misdiagnosed and missed. Conclusion The clinical diagnosis of AOSPD is difficult, early pancreatic duct drainage is the key to the treatment, and attention should be paid to its diagnosis and treatment.

    Release date:2023-02-24 05:15 Export PDF Favorites Scan
  • Research progress of role of Helicobacter pylori on oncogenesis and progression of pancreatic cancer

    Objective To study effects of Helicobacter pylori on oncogenesis and progression of pancreatic cancer. Method The current literatures on the relationship between the Helicobacter pylori and the pancreatic cancer were collected and reviewed. Results The Helicobacter pylori infection might play a role in the development of the pancreatic cancer. The infection rate of the Helicobacter pylori in the patients with pancreatic cancer is higher than that of the healthy controls; furthermore, in the patients with Helicobacter pylori antibody positive, the infection rate of the Helicobacter pylori in the cytotoxin-associated gene A-negative strains of Helicobacter pylori is significantly higher than that of the healthy controls. Conclusions Helicobacter pylori infection is related to occurrence and development of pancreatic cancer. Specific mechanism is still not clarified and further research is need to study.

    Release date:2017-10-17 01:39 Export PDF Favorites Scan
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