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find Keyword "改良" 262 results
  • 大鼠左肺原位移植模型的改进

    目的 建立改进的大鼠左肺原位移植模型,使大鼠肺移植模型的建立更加简便、有效和稳定。 方法 将40只SD大鼠随机配对,采用三袖套法进行肺动、静脉的吻合,内支架进行支气管重建,建立大鼠肺移植模型。 结果 进行大鼠左肺原位移植正式实验20对,供肺灌注到摘取时间为15±3 min,供肺完成体外套管时间为5±2 min,供、受体动静脉和支气管套管吻合时间为30±3 min,总手术时间63±4 min。手术成功18只,手术成功率90%;失败2只,其中操作失误死亡1只,肺静脉撕裂1只。血气、病理学等检查证实成功复制了肺移植缺血再灌注模型。 结论 改进的大鼠左肺原位移植模型操作简便,成功率高,值得推广和应用。

    Release date:2016-08-30 06:05 Export PDF Favorites Scan
  • 改良后的胃管置入法临床应用及效果

    目的观察改良后胃管置入法的临床应用效果。 方法对2012年10月-2013年5月收治的60例需置胃管患者按照就诊顺序分为对照组和改良组,每组30例。对照组采用传统胃管置入法,改良组采用改良胃管置入法。比较两组患者胃管置入过程中发生呛咳、误吸的情况及一次性置管成功率,胃管留置期间胃内容物反流、胃管滑脱发生情况。 结果改良组胃管置入过程中呛咳发生率低于对照组(6.7%、26.7%),一次性置管成功率高于对照组(93.3%、73.3%),差异有统计学意义(P<0.05);改良组置管舒适度优于对照组,差异有统计学意义(Z=-5.093,P<0.001);改良组胃管留置期间胃管脱管率低于对照组,差异有统计学意义(P<0.05)。 结论改良胃管置入法能减少置入过程中患者发生呛咳情况,提高胃管置入成功率,降低胃管留置期间胃管脱管的发生率,值得在临床推广应用。

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  • EFFECTIVENESS OF PENILE VENTRAL SCROTUM COHESION PLACE WEDGE CUTTING AND IMPROVED Brisson TECHNIQUE FOR CONGENITAL BURIED PENIS

    Objective To investigate the effectiveness of the penile ventral scrotum cohesion place wedge cutting and improved Brisson technique for congenital buried penis. Methods Between March 2010 and June 2012, 68 boys with congenital buried penis were treated by the penile ventral scrotum cohesion place wedge cutting and improved Brisson technique, with a median age of 4 years and 10 months (range, 3 months-13 years). Of 68 cases, 14 were classified as phimosis type, 14 as rope belt type, 20 as moderate type, and 20 as severe type. The body of penis developed well and had no deformity. After operation, complications were observed, and the effectiveness was evaluated by the designed questionnaire. Results Early postoperative complications occurred in 11 cases, including obvious adhesion of the outside wrapping mouth in 4 cases, scrotal skin bloat in 5 cases, and distal foreskin necrosis in 2 cases; long-term complications occurred in 9 cases, including abdominal incision scar formation in 4 cases, wrapping mouth scar stricture in 3 cases, and short penis in 2 cases. Primary healing of incision was obtained in the other boys. Fifty-four cases were followed up 6-12 months (mean, 8 months). According to the designed questionnaire, satisfaction rate with the overall view in parents was 77.78% (42/54); the clinical improvement rate was 85.19% (46/54); exposure of the penis was satisfactory in parents of 50 cases; and the parents had no psychological burden of penis exposure in 46 cases, which were significantly improved when compared with preoperative ones (P ﹤ 0.05). The boys had no psychological burden of penis exposure in 29 cases (53.70%) after operation, showing no significant difference when compared with preoperative one (18 cases, 33.33%) (χ2=1.22, P=0.31). Conclusion Application of the penile ventral scrotum cohesion place wedge cutting and improved Brisson technique can effectively correct congenital buried penis.

    Release date:2016-08-31 04:12 Export PDF Favorites Scan
  • MODIFIED Stoppa APPROACH WITH MEDIAL WALL SPRING PLATE FOR INVOLVING QUADRILATERAL OF ACETABULUM FRACTURE

    ObjectiveTo investigate the effectiveness of modified Stoppa approach with medial wall spring plate (MWSP) for involving quadrilateral of acetabulum fracture. MethodsBetween March 2008 and September 2013, 38 patients with involving quadrilateral of acetabulum fracture were treated, including of 23 males and 15 females with an average age of 36.08 years (range, 19-56 years). The causes included traffic accidents injury (21 cases), crash injury of heavy object (10 cases), and falling injury from height (7 cases). The interval of injury and admission was 3 hours to 2 days (mean, 11 hours). There were 12 cases of anterior column fracture (type D), 5 cases of transverse fractures (type E), 8 cases of T shaped fractures (type H), 6 cases of anterior column fracture with posterior transverse fractures (type I), and 7 cases of double column fractures (type J) according to Letournel-Judet classification. Based on fracture types, MWSP was used to fix fracture by modified Stoppa approach in 19 cases or combined with the ilioinguinal approach in 10 cases or combined with Kocher-Langenbeck approach in 9 cases. The operation time, blood loss, and complications were recorded. The effectiveness of reduction and the hip function were evaluated according to Matta score system and Merled' Aubigne and Postel score system. ResultsThe operation time was 85-210 minutes (mean, 130 minutes).The intra-operative blood loss was 450-900 mL (mean, 650 mL). There were 1 case of vascular avulsion, and 1 case of bladder injury during operation; there were 8 cases of venous thrombosis and 2 cases of fat liquefaction of incision after operation. Screw was implanted into the articular joint in 1 case on CT after operation. Matta X-ray assessment showed anatomical reduction in 9 cases, satisfactory reduction in 24 cases, and unsatisfactory reduction in 5 cases, and the satisfaction rate of reduction was 86.84%. Three patients had limb shorting of 0.8-1.0 cm when compared with normal limb. All patients were followed up for 7 to 18 months with an average of 10 months. Fractures healed well within 13-16 weeks with an average of 14 weeks. At 1 year after operation, the results were excellent in 9 cases, good in 21 cases, general in 5 cases, and poor in 3 cases, and the excellent and good rate was 78.95% according to the Merled'Aubigne and Postel hip score standards. ConclusionInvolving quadrilateral of acetabulum fracture can be fixed with MWSP by modified Stoppa approach or combined with other approaches to obtain good exposure, less invasion, satisfactory reduction, stable fixation, and low complications.

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  • 经典生酮饮食和改良阿特金斯饮食治疗儿童难治性癫痫的效果比较

    研究旨在比较改良阿特金斯饮食(Modified Atkins diet,MAD)和经典生酮饮食(Ketogenic diet,KD)在治疗儿童难治性癫痫的疗效、安全性和耐受性。研究纳入 2011 年 3 月—2014 年 3 月就诊的 1~18 岁难治性癫痫患者,将其随机分配至一种饮食治疗组(ClinicalTrials.gov,编号 NCT2100501)。痫性发作记录被用于比较饮食治疗后 3、6 个月痫性发作频率与饮食治疗前基线发作频率。研究纳入 KD 组 51 例患者,MAD 组 53 例患者。KD 组平均基线痫性发作百分比在治疗后 3 个月(KD 组 38.6%,MAD 组 47.9%)和 6 个月(KD 组 33.8%,MAD 组 44.6%)均低于 MAD 组,但差异无统计学意义[3 个月,95%CI (24.1,50.8),P=0.291;6 个月,95%CI(17.8,46.1),P=0.255]。然而,在<2 岁患儿中,KD 组痫性发作控制效果优于 MAD 组。这些患者饮食治疗开始的 3 个月内,KD 组癫痫无发作率高于 MAD 组,差异有统计学意义(KD 组 53%,MAD 组 20%,P=0.047)。MAD 组耐受性更好并且副反应更少。MAD 可能是治疗儿童难治性癫痫的首要选择,但经典 KD 更适合<2 岁患者的一线饮食治疗方案。

    Release date:2018-01-20 10:51 Export PDF Favorites Scan
  • EXPERIMENTAL INVESTIGATION AND CLINICAL APPLICATION OF MODIFIED ECCENTRIC TWO- POINT VASCULAR ANASTOMOSIS

    The author proposed the modified eccen-tric two- point vascular anastomosis by thedetermination of the two point angles fromthe number of stitches needed in anastomo-sis. It was used in 60 superficial abdominalarteries and veins and 63 caudal arteries of70 rats, total of 123 vascular stumps. The in-stantaneous patency rate of the anastomosiswas 100% and the late patency rate was93.3 %. Twelve cases of replantation for am- putated fingers by this method were all sur-vived. The author believed that this method could improve the vascular patenvy of the anastomosed.

    Release date:2016-09-01 11:41 Export PDF Favorites Scan
  • Application of modified keystone flap in repairing of skin and soft tissue defect around joint

    ObjectiveTo explore the effectiveness of keystone flap in repairing skin and soft tissue defects around joint.MethodsBetween March 2013 and December 2017, 10 patients of skin and soft tissue defects around the joint were repaired with keystone flaps. There were 6 males and 4 females. The age ranged from 17 to 72 years, with an average age of 57.5 years. The skin and soft tissue defects located around the joints, including 2 cases of hip joints, 4 cases of knee joints, 3 cases of elbow joints, and 1 case of wrist joint. The cause of skin and soft tissue defects included scar contracture in 3 cases, basal cell carcinoma in 3 cases, squamous-cell carcinoma in 3 cases, and dermatofibrosarcoma protuberant in 1 case. The area of defects ranged from 4 cm×3 cm to 11 cm×11 cm. The keystone flap was designed beside the wound, and the V-shaped flap was designed at the longer side of the fan-shaped flap. The area of flap ranged from 7 cm×3 cm to 35 cm×10 cm. The flap was constantly compressed by vacuum assisted closure after operation for 3-6 days.ResultsPrimary wound healing was achieved and the flaps survived. All patients were followed up 6-24 months (mean, 15 months). The texture and color of flap was similar to the adjacent area. The appearance and function of joint were satisfactory.ConclusionThe keystone flap is a feasible and efficient way to repair the wound around joint. Furthermore, the skin color and texture is similar to the surrounding tissue after healing.

    Release date:2019-05-06 04:46 Export PDF Favorites Scan
  • 新改良LeFort Ⅰ型截骨线在鼻旁凹陷畸形矫治中的应用

    目的 总结新改良LeFort Ⅰ型截骨线在鼻旁凹陷畸形矫治中的应用。 方法 2008 年4 月-2009 年9 月,采用新改良LeFort Ⅰ型截骨线矫治3 例面中部发育不良鼻旁凹陷畸形女性患者。年龄18 ~ 26 岁。均表现为上颌后缩伴明显鼻旁区凹陷及下颌前凸,为Angle Ⅲ类错颌畸形。术前经正畸治疗后,修正SNA 平均为73.6°,SNB 平均为82.7°。 结果 术中出血量400 ~ 600 mL,平均350 mL。术后切口均Ⅰ期愈合,无骨块坏死等并发症发生。3 例均获随访,随访时间6 ~ 23 个月,平均15 个月。畸形无复发,面型稳定无变化,咬调整为Angle Ⅰ类咬。 结论 采用新改良LeFort Ⅰ型截骨线矫治鼻旁凹陷畸形效果理想。

    Release date:2016-08-31 05:48 Export PDF Favorites Scan
  • MODIFIED REVERSE HOMODIGITAL ARTERY ISLAND FLAP FOR REPAIR OF FINGERTIP DEFECT

    Objective To investigate the operative method and cl inical efficacy of repairing fingertip defect with modified reverse homodigital artery island flap. Methods From March 2000 to September 2006, 18 cases (24 fingers) of fingertip defect were treated, including 12 males and 6 females aged 18-53 years (mean 29 years). Defect was caused by crush injuries in 12 cases, by avulsion injury in 3 cases, by twist injury in 2 cases and by incised injury in 1 case. The time from injury tooperation was 2-8 hours (mean 4 hours). The location were index fingers (3 fingers), middle fingers (4 fingers) and ring fingers (17 fingers). The defects of soft tissue were 1.9 cm × 1.7 cm to 2.4 cm × 1.9 cm in size, the reverse homodigital artery island flaps were from 2.0 cm × 1.5 cm to 2.5 cm × 2.0 cm in size. The donor site was repaired with dumped skin grafting(3 cases) and with skin grafting from medial area of planta pedis (15 cases). Results Skin flaps and skin grafting of all the 24 fingers survived after operation. All incisions and donor sites healed by first intention. Sixteen patients (22 fingers) were followed up for 1-5 years (mean 3.2 years).The appearance and function of the flaps were all satisfactory. Two-point discriminations of flaps ranged from 4.5 mm to 6.3 mm. According to the total active movement/total passive movement assessment criteria, the results were excellent in 20 fingers and good in 2 fingers; and the excellent and good rate was 100%. The circumference of donor site was 2.0-3.5 mm shorter than that of normal side. The two-point discriminations of donor site was 7.8-10.5 mm. Conclusion Repairing defect of fingertip with modified reverse homodigital artery island flap can provide good texture and contour matching the recipient area, good function and l ittle trauma at donor site.

    Release date:2016-09-01 09:07 Export PDF Favorites Scan
  • Modified Del Nido cardioplegia versus St.Thomas cardioplegia for myocardial protection in adult patients with combined valve replacement

    Objective To analyze the effect of myocardial protection between modified Del Nido cardioplegia and St. Thomas Hospital Cardioplegia in adult patients with aortic valve and mitral valve replacement. Methods From January 2014 to June 2016, 140 patients underwent aortic valve and mitral valve replacement in our hospital. According to different cardioplegia, the patients were divided into two groups including a modified Del Nido cardioplegia group (70 patients, 37 males, 33 females at mean age of 53.13±9.52 years) and a St. Thomas cardioplegia group (70 patients, 32 males, 38 females, at age of 50.71±9.29 years). We collected clinical data of the patients before operation (T1), 2 h after aortic unclamping (T2), 24 h after operation (T3) and 48 h after operation (T4). Indexes of muscle enzymes including blood center creatine kinase (CK), creatine kinase isoenzyme (CK-MB) concentration and liver function indexes including urea nitrogen (BUN), creatinine (Cr), alanine aminotransferase (ALT), aspartate aminotransferase (AST) concentrations, and compared the postoperative and follow-up clinical data. Results There was no statistical difference in age, weight, gender, ejection fraction baseline data between the two groups (P>0.05). All patients were successfully completed combined valve replacement under cardiopulmonary bypass. The cardiopulmonary time was no statistical difference between the two groups (P>0.05). However, compared with St. Thomas cardioplegia group, modified Del Nido group was less in perfusion (1.19±0.39vs. 2.99±0.75, P<0.001), shorter in aortic clamping time (P=0.003). No statistical difference was found in defibrillation rate after resuscitation between the two groups (P=0.779). Biochemical indicators were not statistically different at different time points between the two groups (P>0.05). Conclusion Modified Del Nido cardioplegia has the same effect on myocardial protection with St. Thomas cardioplegia in adult patients. It reduces the frequency of reperfusion, and shortens the clamping time. There is no additional injury in the important organs such as liver, kidney. Modified Del Nido cardioplegia myocardial protection ability in adult heart valve surgery is feasible.

    Release date:2017-12-29 02:05 Export PDF Favorites Scan
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