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find Keyword "文献" 331 results
  • 抗血管内皮生长因子单克隆抗体Bevacizumab基础和临床研究现状

    眼部新生血管性及渗出性疾病与血管内皮生长因子(VEGF)关系密切,抗VEGF药 物成为治疗此类疾病的突破点。人源化全长抗VEGF抗体Bevacizumab (Avastin) 有2个VEGF 结合位点,能够与所有具有活性的VEGF结合,具有生物相容性好,价格低,玻璃体内半衰期较长等特点。采用该药玻璃体腔注射,是治疗老年性黄斑变性、糖尿病视网膜病变、视网膜 血管阻塞性疾病、黄斑囊样水肿等多种眼部新生血管性及渗出性疾病的一种安全、有效方式 ,但其长期效果和安全性有待多中心研究进一步证实。 (中华眼底病杂志,2008,24:227-231)

    Release date:2016-09-02 05:46 Export PDF Favorites Scan
  • 《中华眼底病杂志 》11年载文量的计量分析

    目的:统计1985~1995年《中华眼底病杂志》所载主要论文,分析研究其特点. 方法: 一次文献分为基础研究,临床研究和临床描述三类,统计每筒论文的版面数、作者和单位数,稿源以及资助情况。 结果:基础研究和临床研究占主要部分,份量逐年增加,平均每篇论文的单位敷和作者数分别为1.3和2.9,有增加趋势,千均每篇论文版面2.3页,呈下降陷势,国际合作和获得资助的论文与年俱增. 结论:11年来我国眼底病的研究着重于基础和临床研究,有多方合作和争取资助增长的趋势. (中华眼底病杂志,1997,13:55-56)

    Release date:2016-09-02 06:12 Export PDF Favorites Scan
  • Literature analysis of complications and predictive factors of amputees during postoperative hospitalization

    Objective To analyze the major complications and predictive factors of amputees during postoperative hospitalization, and provide a reference for amputees nursing and early rehabilitation. Methods Using the bibliometric method, we searched Embase, Ovid, Medline, PubMed, CINAHL, China National Knowledge Infrastructure, Wanfang and CQVIP databases for the data of postoperative hospitalization of amputees published from January 1st, 2008 to April 5th, 2022. Statistical description and analysis of article types, sample size, reasons for amputation, amputation sites, complications, influencing factors, predictive factors, and treatment recommendations were performed.Results Finally, 19 articles were included, including 16 in English and 3 in Chinese, all of which were quantitative studies. The literature quality scores were greater than or equal to 7 points, which were all good or excellent. The type of articles were mainly retrospective research (n=15), and the research contents were mainly lower limb amputation. The main reasons for amputation were peripheral vascular disease and diabetes mellitus (n=11). Wound infection, anemia, phantom limb pain, and psychological problems were common complications after amputation. Predictors of complications, secondary operations, and death included age, gender, smoking, drinking, obesity, preoperative comorbidities, level of amputation, anesthesia methods and other factors. Conclusions The focus of acute care after amputation should be wound healing, pain control, proximal physical movement and emotional support, especially for amputees who have prominent postoperative psychological problems. These patients need early psychological disease screening and mental support. After amputation, multi-disciplinary and multi-team coordinated care are needed to achieve both physical and psychological healing of the patient and promote early recovery.

    Release date:2022-05-24 03:47 Export PDF Favorites Scan
  • 曲安奈德玻璃体腔注射的临床应用

    糖皮质激素制剂曲安奈德玻璃体腔内注射对控制视网膜、葡萄膜和视神经的炎症,抑制增生性玻璃体视网膜病变(proliferative vitreoretinopathy, PVR)和视网膜、脉络膜 及虹膜的新生血管形成以及治疗各种病变所 致的黄斑水肿显示出良好的临床效果和较为广泛的应用前景。但对其眼科应用的适应证、剂 型和给药剂量、远期疗效以及副作用还需进一步总结研究,注意防止临床滥用现象的发生。 (中华眼底病杂志,2003,19:201-268)

    Release date:2016-09-02 06:00 Export PDF Favorites Scan
  • 关于英文摘要中作者姓名拼写的基本要求

    根据中国文字改革委员会《中国人名汉语拼音字母拼写法》(1974年)的规定:(1)中国人名分汉语姓名和少数民族语姓名。用汉语拼音字母拼写姓名,汉语姓名按照普通话拼写,少数民族语姓名按照民族语拼写。如邓小平DENG Xiao-ping。(2)少数民族语姓名按照民族语,用汉语拼音字母音译转写。如阿沛?阿旺晋美Ngapoi Ngawang Jigme。

    Release date:2016-09-02 05:26 Export PDF Favorites Scan
  • Retrospective Analysis of Echinococcosis Outside Liver in China

    ObjectiveTo summarize regional and body distributions, diagnosis, treatment, and prognosis of echinococcosis outside liver in China. MethodsThe published literatures about echinococcosis outside liver in China (not including Hong Kong, Macao and Taiwan regions) from 2000 to 2015 were searched in the databases of CNKI and Wanfang. Data were extracted by using a standardized form and a retrospective clinical analysis was performed. ResultsA total of 66 published literatures about echinococcosis outside liver and data of 884 cases reported were collected. The regional proportions of cases reported were different, five high regions were Xinjiang (68.73%), Tibet (8.77%), Ningxia (6.75%), Qinghai (6.41%), Gansu (5.62%). The organ distributions of cases reported were also different, five high organs were lung (61.09%), bone (9.95%), brain (9.73%), spleen (8.60%), and kidney (6.22%). The main clinical symptoms of patients with echinococcosis outside liver included general asymptoms and organ dysfunction, and the most common examinations were X-ray (30.77%), B ultrasound (7.47%),CT(17.43%), MR (1.59%), and laboratory (36.31%). The main therapy choice was operation (73.30%), and some patients were performed operation combined with drug therapy. ConclusionRegional distribution of echinococcosis outside liver is almost the same as total echinococcosis, and distributed more in organs rich in blood supply, its clinical diagnosis mainly depends on imaging and immunology examination, and operation is still the main therapy choice.

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  • 睫状神经营养因子对视神经损伤修复作用的研究进展

    以往认为,成年哺乳动物视神经损伤后通常不能再生。视神经损伤后,其轴突很快发生变性,胞体死亡,这是个不可逆的过程。但近年来的实验研究发现,视神经轴突可长入移植的周围神经,并且认为在再生过程中,睫状神经营养因子发挥了重要作用,现就睫状神经营养因子及其受体的分子结构、组织分布、基因结构及其在视神经损伤后的作用和作用机制作一综述,为视神经损伤的治疗提供了理论基础。 (中华眼底病杂志,2003,19:333-404)

    Release date:2016-09-02 06:00 Export PDF Favorites Scan
  • 更正一则

    本刊2012年第4期ldquo;中国人眼白化病1型的临床特点观察rdquo;一文的对象和方法中,ldquo;A型:虹膜色素轻微沉着不足(图2A),hellip;hellip;;B型:虹膜色素沉着不均匀(图2B),hellip;hellip;;C型:虹膜呈大片状色素缺失(图2C),hellip;hellip;rdquo;。应为ldquo;A型:虹膜色素轻微沉着不足(图2A,2B),hellip;hellip;;B型:虹膜色素沉着不均匀(图2C),hellip;hellip;;C型:虹膜呈大片状色素缺失(图2D),hellip;hellip;rdquo;。特此更正,并向作者、读者表示歉意。

    Release date:2016-09-02 05:26 Export PDF Favorites Scan
  • 炎症与脉络膜新生血管

    Release date:2016-09-02 05:48 Export PDF Favorites Scan
  • Bibliometric and visualized analysis of peripheral magnetic stimulation

    Objective To conduct a bibliometric analysis of research hotspots and development trends in the application of peripheral magnetic stimulation (PMS), systematically review the research evolution, and provide references for future studies. Methods We retrieved PMS-related literature from the Science Citation Index Expanded database in Web of Science Core Collection (January 1, 1989 - March 5, 2025). Using VOSviewer (v1.6.20) and CiteSpace (v6.1.R6), we performed annual publication volume analysis, country/institution/author collaboration network analysis, reference co-citation analysis, and keyword co-occurrence/clustering/burst analysis, with corresponding knowledge mapping visualizations. Results A total of 124 publications were included. Both publication counts and citation frequencies remained low in early years but showed steady annual growth after 2011. The publications originated from 21 countries/regions, with Germany being the most productive nation, Technical University of Munich the leading institution, and Schneider C (from the Research Center of Neuroscience and Rehabilitation Sciences, Laval University, Canada) the most prolific author. Keyword analysis revealed three major research clusters: neuromodulation technologies, physiological mechanisms, and clinical rehabilitation applications. Future research priorities included expanded clinical applications integrating neuroelectrophysiological indicators with rehabilitation assessments, and interdisciplinary optimization of stimulation parameters through engineering approaches. Conclusions PMS has gained widespread clinical application with growing scientific interest. Future studies should focus on current hotspots to advance precision and intelligent development of this technology.

    Release date:2025-07-29 05:02 Export PDF Favorites Scan
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