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find Author "武忠" 26 results
  • Research and clinical application progress of cardiac mapping in the electrophysiological mechanism of atrial fibrillation

    Atrial fibrillation is one of the most common arrhythmia. Cardiac mapping technology, an important method to study the electrophysiological mechanism of atrial fibrillation, can determine the abnormal origin and record the distribution and transmission way of these atrial electrical signals. This technology offers a new way for research the electrophysiological mechanism of atrial fibrillation. The purpose of this study is to review the research progress of cardiac mapping in the electrophysiological mechanism of atrial fibrillation and clinical application.

    Release date:2017-07-03 03:58 Export PDF Favorites Scan
  • Advances in artificial intelligence in prediction of atrial fibrillation

    Atrial fibrillation (AF) is one of the most common arrhythmias. Today, there are a large number of AF patients worldwide, and incidence increases with the increase of age. However, the current diagnosis rate of AF via auxiliary examination is relatively low. In view of the widespread application of artificial intelligence (AI) in the medical field, the diagnosis of AF using AI has also become a research hotspot. This article briefly introduces the relevant aspects of AI and reviews the application of AI in AF prediction.

    Release date:2020-12-31 03:27 Export PDF Favorites Scan
  • Research Progress in Cell Transplantation for Treatment of Myocardial Infarction

    The capacity for self-regeneration of the adult heart is very limited, conventional therapies cannot solve the loss of cardiomyocytes in the infarcted heart leads to continuous ventricular remodeling. Cell transplantation therapy is emerging as a novel approach for myocardial repair over conventional therapies. Various types of cell transplantation have improved cardiac function and angiogenesis in animal models and clinical settings. The safety and feasibility of some clinical trials have been initiated. In this review, we summarize the advantages and limitations of different cell types proposed for cell transplantation in myocardial infarction and give an overview of the clinical trials using this novel therapeutic approach in patients with myocardial infarction.

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  • 同种瓣的制作与临床应用

    目的报告液氮深低温下保存同种带瓣血管的制作方法、组织活性及临床应用效果。方法制作同种瓣24个、抗生素灭菌、梯度降温后置于液氮中保存,并测定冷冻保存后同种瓣的组织活性。同种瓣临床应用5例,其中法洛四联症、肺动脉闭锁2例,先天性主动脉瓣狭窄1例,法洛四联症术后发生室间隔缺损残余漏伴肺动脉瓣重度关闭不全1例,Bentall术后发生感染性心内膜炎1例。结果抗生素灭菌、液氮深低温技术保存同种瓣具有良好的组织活性,糖代谢测定24h葡萄糖消耗大于16mg/dl,组织培养见成纤维细胞生长良好。临床移植5例均成功,术后随访3~8个月,同种瓣无狭窄或关闭不全。结论液氮深低温保存同种瓣安全可靠,临床应用早期效果良好。

    Release date:2016-08-30 06:25 Export PDF Favorites Scan
  • Effect of 3D-printed heart model on congenital heart disease education: A systematic review and meta-analysis

    Objective To evaluate the effect of the 3D-printed heart model on congenital heart disease (CHD) education through systematic review and meta-analysis. Methods The literature about the application of the 3D-printed heart model in CHD education was systematically searched by computer from PubMed, Web of Science, and EMbase from inception to November 10, 2022. The two researchers independently screened the literature, extracted data and evaluated the quality of the literature. Cochrane literature evaluation standard was used to evaluate the quality of randomized controlled trials, and JBI evaluation scale was used for cross-sectional and cohort studies. ResultsAfter screening, 23 literatures were included, including 7 randomized controlled trials, 15 cross-sectional studies and 1 cohort study. Randomized controlled trials were all at low-risk, cross-sectional studies and and the cohort study had potential bias. There were 4 literatures comparing 3D printing heart model with 2D image teaching and the meta-analysis result showed that the effect of 3D printing heart model on theoretical achievement was more significant compared with 2D image teaching (SMD=0.31, 95%CI –0.28 to 0.91, P=0.05). Conclusion The application of the 3D-printed heart model in CHD education can be beneficial. But more randomized controlled trials are still needed to verify this result.

    Release date:2024-08-02 10:43 Export PDF Favorites Scan
  • 心内直视下射频消融改良迷宫术治疗心房颤动

    目的 总结心内直视下射频消融改良迷宫手术治疗心房颤动的临床经验。 方法 2005年5月~2006年8月在心内直视手术同期采用射频消融改良迷宫手术治疗心房颤动30例,术前诊断风湿性心脏病26例,二尖瓣关闭不全3例,冠心病1例。手术采用Cardioblate TM冲洗式射频消融系统,每例患者分别应用单极系统和双极系统,按照迷宫手术线路分别于左、右心房行心内膜射频消融手术,并切除左、右心耳,同期完成相应的心脏手术。 结果 手术均顺利完成,射频消融手术时间30.5±12.6 min。术后死亡1例,其余29例顺利出院。术后当天21例患者(70.0%)转为窦性心律。29例患者出院后随访7.6±4.8个月,24例(82.8%)为窦性心律,5例(17.2%)为心房颤动或房室结性心律。 结论 心内直视下射频消融改良迷宫手术治疗心房颤动简单、有效,具有良好的临床应用前景。

    Release date:2016-08-30 06:16 Export PDF Favorites Scan
  • 起源于二尖瓣瓣环的心脏粘液瘤一例

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  • Safety of the removal of pericardial and mediastinal drain within a different drainage volume after cardiac valvular replacement surgery: A case control study

    ObjectiveTo assess the safety of the removal of pericardial and mediastinal drain within different drainage volume after cardiac valvular replacement surgery.MethodsBetween July 2013 and July 2017, 201 patients with rheumatic heart disease (CHD) were treated with valve replacement in our hospital, including 57 males and 144 females, aged 15 to 72 years. They were divided into two groups according to the amount of 24-h drainage before the drain removal: a group one with 24-h drainage volume≤50 ml (n=127) and a group two with 24-h drainage volume>50 ml (n=74). The postoperative hospital stay and the incidence of severe complications between the two groups were compared.ResultsThere was no difference between the two groups in the baseline information or the incidence of severe pericardial effusion and tamponade, while the group two tended to have a shorter length of hospital stay after surgery (8.0 d vs. 7.5 d, P=0.013).ConclusionIn CHD patients undergoing valvular surgery, compared with a relatively low amount of drainage before the drain removal, drawing the tube at a greater amount of drainage (24-h drainage volume>50 ml) will shorten the length of hospital stay after cardiac surgery while incidence of severe complications remains the same.

    Release date:2019-01-03 04:52 Export PDF Favorites Scan
  • 心脏直视手术围术期尿微量蛋白变化的临床观察

    目的 观察心脏直视手术围术期尿微量蛋白的变化并分析其临床意义.方法 40例心脏直视手术患者按疾病种类不同分为两组,组Ⅰ:风湿性心脏病瓣膜置换术患者(n=20);组Ⅱ:非紫绀型先天性心脏病患者(n=20).采用速率散射比浊法分别于术前1天,手术结束时,术后1天,术后3天和术后5天测定微白蛋白、转铁蛋白、免疫球蛋白G和α1-微球蛋白的浓度变化.结果 两组术后微白蛋白、转铁蛋白、免疫球蛋白G和α1-微球蛋白的浓度均明显升高(P<0.05或P<0.01),到达峰值后逐渐下降.两组比较,组Ⅰ术后改变较明显,持续时间也较长(P<0.05或P<0.01).结论 心脏直视术后存在不同程度的肾脏损害,风湿性心脏病瓣膜置换术患者术后的肾脏损害较重.尿微量蛋白测定可以敏感、准确地发现心脏直视术后亚临床肾脏损害.

    Release date:2016-08-30 06:35 Export PDF Favorites Scan
  • 肺动脉高压靶向药物在慢性血栓栓塞性肺动脉高压中的应用现状

    Release date:2023-01-18 06:43 Export PDF Favorites Scan
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