ObjectiveTo investigate the status of quality of life and influencing factors among newly diagnosed epilepsy patients with co-morbid anxiety and depression. MethodsA total of 180 newly diagnosed epilepsy patients from June 2022 to December 2022 in a district of Shanghai were selected as the study subjects. The Quality of Life in Epilepsy-31 (QOLIE-31), Hamilton Depression Rating Scale (HAMD-24), Hamilton Anxiety Rating Scale (HAMA), and Epilepsy Self-Management Scale (ESMS) were used to assess patients' quality of life, depression levels, anxiety levels, and self-management abilities, respectively. Patients were divided into the co-morbid depression group (HAMA≥14 and HAMD>17) and the control group (HAMA<14 and HAMD≤17), and their general characteristics and scale scores were compared. Spearman correlation, Pearson correlation, and multiple linear regression analysis were used to identify influencing factors of quality of life in epilepsy patients with co-morbid depression. ResultsCompared to the control group, the anxiety comorbid with depression group of older adults had a higher proportion, higher unemployment rate, lower personal and family annual income in the past year, higher frequency of epileptic seizures, and lower medication adherence (P<0.05). The correlational analysis revealed a negative correlation between the quality of life abilities of epilepsy patients with comorbid anxiety and depression and the severity of anxiety and depression. (r=−0.589, −0.620, P<0.05). The results of multiple linear regression analysis showed that the frequency of seizures in the past year (β=−1.379, P<0.05), severity of anxiety (β=−0.279, P<0.05), and severity of depression (β=−0.361, P<0.05) have an impact on the ability to quality of life in epilepsy patients with co-morbid anxiety and depression. These factors account for 44.1% of the total variability in quality of life (R2=0.4411, P<0.05). ConclusionThe frequency of seizures in the past year, as well as the severity of anxiety and depression, are important factors that influence the ability to quality of life in epilepsy patients with comorbid anxiety and depression. For these patients, it is crucial to take into account these factors and provide appropriate support and interventions.
Objectives To analyze the prevalence and clinical features of depression, anxiety, depression and anxiety in Tibetan patients with epilepsy and to improve the diagnosis and treatment. Methods 102 patients with epilepsy, who had been admitted to the Department of Neurology of the People's Hospital of Tibet Autonomous Region from January 2017 to December 2017, were diagnosed according to the Chinese Standard Classification and Diagnostic Criteria for Mental Disorders (3rd Edition) (CCMD-3). The Hamilton depression scale (HAMD 24 items) and the Hamilton anxiety scale (HAMA 14 items) were used to measure depression and anxiety. Different genders, ages, durations, frequency of attacks, and seizures types were analyzed for depression, anxiety, depression and anxiety. Univariate analysis was used to screen the factors that may cause depression, anxiety, depression and anxiety in patients with epilepsy. Logistic regression was used to analyze the risk factors of depression, anxiety, depression and anxiety in patients with epilepsy. Results Among the 102 patients with epilepsy, 35 (34.31%) comorbid depression, 10 (9.80%) comorbid anxiety, and 54 (52.94%) comorbid depression and anxiety. Univariate analysis showed that there was a significantly statistical difference in the duration of the disease and the frequency of seizures in local patients with epilepsy (P<0.05). There was a statistically significant difference in the frequency of epileptic seizures and anxiety (P<0.05). Multivariate logistic regression analysis showed that the probability of anxiety in patients with a disease duration of ≤2 years was only 10.1% of those with a course >2 years [OR=0.101, 95%CI (0.012, 0.915), P<0.05]; and the frequency of seizures was not an risk factors for epileptic comorbid with anxiety (P>0.05). The rate of depression and anxiety in patients with seizure frequency >2 times per month was 4.853 times higher than that of patients with seizure frequency ≤2 times per month [OR=4.853, 95%CI (2.024, 11.634), P<0.05]. Conclusions Tibetan patients with epilepsy have a high prevalence of depression, anxiety, depression and anxiety. In the diagnosis and treatment, we should strengthen the understanding and provide the appropriate prevention and treatment to improve the diagnosis and treatment level.
【摘要】 目的 了解结直肠癌患者术后发生抑郁、焦虑状况，分析其影响因素。 方法 2010年1-3月，采用Zung抑郁自评量表（SDS）、焦虑自评量表（SAS）和一般资料调查问卷，结合病历资料及心理评估，对64例结直肠癌术后患者进行测评，采用SPSS 13.0软件对数据进行统计分析。 结果 64例患者SDS（47.02±10.38）分，SAS评分（42.42±7.96）分，均高于国内常模（Plt;0.001）。抑郁和焦虑发生率分别为42.2%、20.3%。造口患者抑郁得分高于非造口患者（P=0.004），Miles术患者抑郁得分高于非造瘘根治术患者（P=0.039），姑息术患者抑郁得分高于非造瘘根治术患者（P=0.007）；家庭月收入≤1 000元者抑郁得分高于1 001~3 000元及gt;3 000元者（P=0.040，0.017）。不同情况患者焦虑得分差异无统计学意义（Pgt;0.05）。SDS与SAS呈正相关（Plt;0.001）。 结论 结直肠癌术后患者存在不同程度的抑郁和焦虑。护理人员尤其应关注造口术后、晚期患者及收入低下患者，并进行针对性健康教育和心理干预。【Abstract】 Objective To evaluate the postoperative anxiety and depression of patients with colorectal cancer and investigate its related factors. Methods From January to March 2010, 64 patients who were diagnosed to have colorectal cancer and received therapeutic operations were investigated with self-rating depressive scale (SDS), self-rating anxiety scale (SAS) and self-made related questionnaire respectively. Psychological assessment and medical records gathering were also carried out. The data collected were analyzed by SPSS 13.0. Results The total score of SDS (47.02±10.38) and SAS (42.42±7.96) of the 64 patients were both higher than those of the general population (Plt;0.001). The incidence rate of depression and anxiety was 42.2% and 20.3% respectively. Patients without stoma had lower SDS scores than those with stoma (P=0.004); patients undergoing Miles operation had higher SDS scores than those receiving non-fistula formation radical operations (P=0.039); patients receiving palliative treatment had higher SDS scores than those receiving non-fistula formation radical operations (P=0.007); patients with family monthly income less than 1 000 RMB had higher SDS scores than those with more than 3 000 RMB and between 1 001-3 000 RMB (P=0.017, 0.040). SAS scores among different patients were not significantly different (Pgt;0.05). SDS had positive correlation with SAS (Plt;0.001). Conclusions Patients with colorectal cancer have higher emotions of anxiety and depression after operation than those in the general population. It is suggested that more psychological consultation, treatment and nursing should be carried out to promote the overall physical and mental rehabilitation of the patients, especially for those having undergone stoma formation, late-stage patients and those with a low income.
Objective To identify related factors of anxiety and depression in spinal cord injury (SCI) patients based on patient-environment-occupation (PEO) model, and provide evidences for clinical practice. Methods A total of 241 patients with SCI treated between April 2014 and April 2015 were collected as the study subjects. All the patients were confirmed with SCI through CT or MRI, and had physical dysfunction. Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) were applied in all the 241 SCI patients to measure their psychological state. Meanwhile, PEO factors such as demographic information as well as ability of activities of daily living (ADL) and relatives’ stress were assessed by self-made questionnaire, Modified Barthel Index (MBI) and Relatives’ Stress Scale (RSS). Then, multiple stepwise regression was applied to identify significant covariance with SAS/SDS as dependent variables and other 14 factors as independent variables. Results The regression equation showed that only SDS, MBI, living environment and disease course were significantly associated with SAS. Only SAS, MBI and RSS were significantly associated with SDS. Conclusions The ability of ADL and environment are significantly correlated with psychological state of SCI patients. Early intervention of ADL and decreasing environmental barriers are needed to improve patients’ psychological state.
ObjectiveTo explore the correlation between quality of life and social support and anxiety level in children with epilepsy. MethodsA total of 207 children with epilepsy and their parents from March 2023 to December 2023 from Shanghai Children's Hospitalwere selected as the investigation objects, and the children's quality of life scale, Children's perceptive Social support Scale and PROMIS parental Report version anxiety brief form were used to investigate. The correlation between the quality of life of children with epilepsy and the level of social support and anxiety was analyzed. ResultsThe results of univariate analysis showed that the quality of life of children with epilepsy was affected by whether they had siblings and the frequency of onset in the past month (P<0.05). Pearson correlation analysis showed that social support was positively correlated with quality of life (P<0.05). The scores of anxiety and quality of life were negatively correlated (P<0.05). Social support was negatively correlated with anxiety scores (P<0.05). The results of multiple linear regression analysis showed that siblings, social support and anxiety were independent factors affecting the quality of life of children with epilepsy (P<0.05). ConclusionSocial support has a positive effect on the quality of life of children with epilepsy, anxiety level has a negative effect on the quality of life, and social support has a negative effect on anxiety. Therefore, clinical psychological support should be strengthened for children with epilepsy, fully mobilize their positive psychological factors, reduce their anxiety and other negative emotions, play a full range of social support, to achieve the goal of improving the quality of life.