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find Keyword "监测" 189 results
  • Establishing Medical Risk Monitoring and Early Warning System for Quality Improvement and Patient Safety

    Release date:2016-08-25 03:34 Export PDF Favorites Scan
  • Surgery for the treatment of low-grade glioma secondary epilepsy−analysis of 45 cases

    ObjectiveTo explore the clinical characteristics and surgical effect of low-grade glioma (LGG) secondary epilepsy.Methods45 cases of low-grade glioma secondary epilepsy were retrospectively studied during December 2010 and December 2020.There were 27 males and 18 females in this group. Their ages ranged from 10 to 69 years [mean (42.8±15.61) years]. And the illness duration ranged from 3 months to 5 years [mean (12.5±4.12) months]. The initial manifestation of all LGG was seizure attack.All the patients underwent CT and MRI examination before the operation. The LGG was located in the frontal lobe in 17 cases, temporal lobe in 8 cases, parietal lobe in 4 cases, frontal-temporal lobe in 7 cases, frontal-parietal lobe in 5 cases. Meanwhile the LGG was located in the left side in 31 cases, right side in 14 cases. The long-term video-EEG monitoring showed the epileptogenic lesion was located in the ispilateral frontal lobe in 20 cases, temporal lobe in 8 cases, frontal-temporal lobe in 12 cases, frontal-parietal lobe in 5 cases.All the patients were performed operation under the intra-operative electrocorticography (ECoG) monitoring.If necessary, enlarged epileptogenic cortical resection, cortical coagulation or MST was added.After the operation, all the patients were followed-up for half a year to 10 years [mean (4.7±1.83) years] to observe the surgical effect.Results42 cases of LGG underwent gross total resection and 3 subtotal resection intra-operatively. Anterial temporal lobectomy (ALT) was added in 19 cases whose LGG were invovled with temporal lobe.13 cases were added cortical cogulation and 5 cases MST.The post-operative pathology showed astrocytoma grade Ⅰin 20 cases, astrocytoma grade Ⅱ in 12 cases, oligodendroglioma in 11 cases and dysembryoplastic neuroepithelial tumor (DNET) in 2 cases. The post-operative follow-up showed that 30 cases lived well, 12 cases recurred and received re-operation, 3 cases died. Meanwhile, 42 cases were seizure free and 3 cases had occasional seizure attack during the follow-up.ConclusionsTo the patients with LGG secondary epilepsy, if pre-operative long-term EEG monitoring is in accordance with imaging examination, early LGG resection combined with epileptogenic lesion resection should be performed under the guidance of ECoG monitoring.And the post-operative effect is satisfactory.

    Release date:2021-12-30 06:08 Export PDF Favorites Scan
  • Clinical Study of Gastroesophageal Reflux and Gastric Emptying after Esophagectomy with Gastric Replacement Through Esophageal Bed

    Abstract: Objective To evaluate the effect on gastroesophageal reflux and gastric emptying in the different route of gastroesophageal anastomosis objectively after esophagectomy for patients with midesophageal carcinoma. Methods Forty patients with midesophageal carcinoma were randomly divided into two groups. Esophageal bed group (n=20): the gastroesophageal anastomosis were performed while the stomach were pulled on through the esophageal bed after esophagectomy; endothoracic group (n=20): gastroesophageal anastomosis were performed while the stomach were pulled on in the thoracic cavity. Ten persons had no disease of digestive system and healthy volunteers were recruited as normal control group. 24-hour esophageal pH monitoring and radioisotope gastric emptying checkup were carried out in all experimental subjects 3 months after operation, so as to observe the changes of gastroesophageal reflux and gastric emptying. Results All of the patients’s operation were success. And no anastomotic leakage and no anastomotic stenosis. Three months after operation, the patients in both operation groups were with different level of reflux. DeMeester total appraise score, the times of regurgitation of gastric juice in 24h, gt;5 min reflux frequency, the longest time of keep reflux, pHlt;4.00 total time and pHlt;4.00 of total time percent, these targets in both operation groups were higher than those in control group (Plt;0.01) DeMeester total appraise score, the times of regurgitation of gastric juice in 24 hours, the longest time of keeping reflux, pHlt;4.00 of total time and pHlt;4.00 of total time percent in esophageal bed group were lower than those in endothoracic group(Plt;0.01). The recent period of gastric emptying percentage (GE) in both operative groups were lower than that in normal control group. GE in esophageal bed group experimental meal in the stomach after entering the 30,60,90,120,180 and 240 min were higher than those in endothoracic group. Conclusion After the operation of esophagogastric anastomosis through esophageal bed in upper aortic site,gastroesophageal reflux and delayed gastric emptying exist objectively, However, the technique is superior to the traditional technique to reduce the extent of gastroesophageal reflux and delayed gastric emptying, its mechanism might be the result of mechanical factors.

    Release date:2016-08-30 06:16 Export PDF Favorites Scan
  • 医院感染非发酵革兰阴性杆菌的耐药研究

    摘要:目的: 监测综合性医院医院感染非发酵革兰阴性杆菌的分布和耐药状况。为临床用药和控制医院感染提供参考。 方法 : 收集我院2006年7月1日至2009年6月30日548株非重复的医院感染非发酵革兰阴性杆菌,复核后采用琼脂稀释法进行体外敏感试验,按照美国临床和实验室标准协会(CLSI)2007年的标准测定MIC,以MIC50 和MIC50 表示抗菌药物的抗菌活性,并计算出耐药率(R%),中介率(I%)和敏感率(S%)。 结果 : 14种抗菌药物对铜绿假单胞菌的抗菌活性敏感率从大到小依次为:美罗培南(81.5%),哌拉西林∕三唑巴坦(77.8%),亚胺培南(73.6%),阿米卡星(72.7%)。鲍曼不动杆菌对亚胺培南,美罗培南,左氧沙星,头孢吡肟敏感性最高,敏感率分别为:78.5%,72.4%,69.5%,62.8%。 结论 : 2种非发酵菌是一组多重耐药且耐药率较高的细菌,临床应根据药敏结果选用抗菌药物。

    Release date:2016-09-08 10:12 Export PDF Favorites Scan
  • EXPERIMENTAL STUDY OF THE MECHANISM ON BLOOD SUPPLY TO DELAYED SEPARATED SKIN FLAP BY ULTRASONIC DOPPLER

    In order to investigate the mechanism of blood supply to the delayed separated skin flap and the time and criteria for its transfer, 5 smallsized Banna pigs were selected to produce 14 skin flaps. In the experimental group the skin flap on one side was made from the middle of the back having an extrathin steel sheet intervened between the flap and the soft tissue of the back whereas the flap on the opposite side without a steel sheet intervened was served as the selfcontrol. The skin flaps were examined 3,7,10 and 20 days after the operation and 3,7 and 10 days after transfer, respectively, by (1) gross observation; (2) ultrasonic Doppler; (3) superficial skin temperature measurement and; (4) histomorphological examination. In the experimentalgroup the survival rate of the flap was 100 percent whereas in the control group all of the flaps had necrosis from 30 to 50 percent after the flap being transfered. In the experimental group, the echo sound from the arterial blood flow from ultrasonic Doppler was heard at the pedicle 7 days after the operation, and as time elapsed, the echo sound spread distally, whereas in the controls no echo sound could be heard over the skin flap. There was significant difference statistically between the experimental and control groups in the temperature of the flaps while the flaps were being transferred (P lt; 0.01). The external diameters of the blood vessels in the central area of the skin flap were larger in the experimental group, 0.8 to l.2mm in comparison to 0.4mm.

    Release date:2016-09-01 11:08 Export PDF Favorites Scan
  • 膈肌电活动的监测与应用

    膈肌是最主要的呼吸肌, 大约70% 的呼吸功由膈肌承担。在危重病和慢性阻塞性肺疾病等慢性疾病患者中, 常发生膈肌功能障碍, 从而导致呼吸窘迫、呼吸衰竭、机械通气时间延长、呼吸肌依赖及撤机失败。监测膈肌电活动可用于评价膈肌功能及神经肌肉疾病的诊断与治疗。因此, 了解膈肌电活动的监测及应用具有重要意义。

    Release date:2016-08-30 11:53 Export PDF Favorites Scan
  • CLINICAL STUDY ON EFFECT OF KEEPING PERIOPERATIVE NORMAL BODYTEMPERATURE ON SKIN FLAP SURVIVAL

    Objective To investigate the effect of perioperative body temperature on the survival of skin flap grafting. Methods From July 2005 to November 2006, 50 cases of Ⅰ-Ⅱ grade patients undergoing elective skin flap grafting were randomly divided 2 groups. Pharyngeal temperature (PT) and skin temperature(ST) were monitored and recorded every 15 minutes. Operativetime, anesthetic time, time from the end of operation to extubation, the volume of blood transfusion, the volume of fluid transfusion and the flap survival 7 days after operation were recorded. In the experimental group, the body temperature was maintained in normal range with water market and forced air heater. In the control group, the body temperature was only monitored without any treatment. Results There were no significant differences in operating room temperature, operative time, anesthetic time, the volume of blood transfusion and fluid transfusion between 2 groups(Pgt;0.05). After induction, PT decreased gradually inboth groups during the first 45 minutes, compared with the time point of intubation(Plt;0.05),but there were no significant differences between the 2 groups(Pgt;0.05); and ST rose in both groups during the first45 minutes, compared with the time point of intubation (Plt;0.05). After 45 minutes of induction, in the experimental group, PT was in the normal range(36℃), and ST didn’t change compared with that of the timepoint of induction(Pgt;0.05). In the control group, both PT and ST decreasedgradually and timedependently compared with the time point of intubation (Plt;0.05). In the experimental group, PT and ST at each time point were higher than those in the control group (Plt;0.05). All the skin flap grafts survived in the experimental group, and skin flap grafts necrosed in 2 cases in the control group.Conclusion Keeping normal body temperature can improve the survival ofskin flap grafting. Therefore, the body temperature should be monitored and maintained in a normal range.

    Release date:2016-09-01 09:23 Export PDF Favorites Scan
  • Molecular Imaging of Islet Transplantation:Tracking and Monitoring

    Objective To summarize and analyze the different modality on molecular imaging of tracking and monitoring for islet transplantation.Methods The current domestic and foreign reports on molecular imaging of islet transplantation were reviewed.Results Magnetic resonance imaging has high sensitivity,high spatial resolution,no ionizing radiation,is clinically applicable,and could be used of real-time MR-guided injections,but can’t discriminate between liver and dead cells,difficult to do in patients with liver iron overload.Nuclear molecular imaging only displays liver cells generate signal,is clinically applicable,but disadvantage is genetic manipulation,ionizing radiation,no anatomical information,low spatial resolution.The advantage of in vivo optical imaging is only liver cells generate signal,widely available,no ionizing radiation,and the disadvantage is genetic manipulation,not clinically applicable,low spatial resolution.Conclusions Islet imaging using magnetic resonance,nuclear molecular imaging,in vivo optical imaging,or multimodal imaging of microencapsulated islets may provide us with a direct means to interrogate islet cell distribution,survival,and function.Multimodal imaging of microencapsulated islets may be best way for tracking and monitoring in the future.

    Release date:2016-09-08 10:36 Export PDF Favorites Scan
  • Research and application of photovoltaic cell online monitoring system for animal robot stimulator

    Power supply plays a key role in ensuring animal robots to obtain effective stimulation. To extending the stimulating time, there is a need to apply photovoltaic cells and monitor their parameter variations, which can help operators to obtain the optimal stimulation strategy. In this paper, an online monitoring system of photovoltaic cells for animal robot stimulators was presented. It was composed of battery information sampling circuit, multi-channel neural signal generator, power module and human-computer interaction interface. When the signal generator was working, remote navigation control of animal robot could be achieved, and the battery voltage, current, temperature and electricity information was collected through the battery information sampling circuit and displayed on the human-computer interaction system in real time. If there was any abnormal status, alarm would be activated. The battery parameters were obtained by charging and discharging test. The battery life under different light intensity and the stimulation effect of neural signal generator were tested. Results showed that the sampling errors of battery voltage, current and electric quantity were less than 15 mV, 5 mA and 6 mAh, respectively. Compared with the system without photovoltaic cells, the battery life was extended by 148% at the light intensity of 78 320 lx, solving the battery life problem to some extent. When animal robot was stimulated with this system, left and right turns could be controlled to complete with the success rate more than 80%. It will help researchers to optimize animal robot control strategies through the parameters obtained in this system.

    Release date:2022-12-28 01:34 Export PDF Favorites Scan
  • 使用表皮肌电监测来检测全面强直-阵挛发作

    该前瞻性多中心Ⅲ期临床试验的目的在于评估在癫痫监测单元(Epilepsy monitoring unit,EMU)中使用可穿戴的表皮肌电图(surface electromyographic,sEMG)监测系统来检测全面强直-阵挛发作(Generalized tonic–clonic seizures,GTCS)的性能和耐受性。199 例有 GTCS 病史的患者被收入 11 个Ⅳ级癫痫中心的 EMU 中,在进行临床视频脑电图(VEEG)监测的同时,也通过在肱二头肌上佩戴可穿戴设备接受了 sEMG 监测。所有 sEMG 数据记录都使用先前开发的检测算法在中心站点处理。将 sEMG 检测到的 GTCS 与 3 名评审专家验证的发作事件进行比较。在所有受试者中,检测算法共检测到了 46 次 GTCS 中的 35 次[76%,95%CI(0.61,0.87)],阳性预测值(Positive predictive value,PPV)为 0.03,平均误报率(False alarm rate,FAR)为 2.52/24 h。对于在肱二头肌中线上方记录到的数据,系统检测到了全部的 29 例 GTCS[100%,95%CI(0.88,1.00)],检测时间平均延迟 7.70 s,PPV 为 6.2%,平均 FAR 为 1.44/24 h。28%(55/199)报告了轻至中度的不良事件,并导致 9% 的研究中止(17/199)。这些不良事件主要是电极贴片引起的皮肤刺激反应,这种情况未经治疗即可缓解。研究中无严重不良事件报告。在肱二头肌上使用 sEMG 监测装置来检测 GTCS 是可行的。正确放置该装置对于检测准确性至关重要,但是对于一些患者而言,减少误报数仍有一定难度。

    Release date:2018-05-22 02:14 Export PDF Favorites Scan
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