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find Keyword "研究进展" 170 results
  • RESEARCH PROGRESS OF VISCOSUPPLEMENTATION

    Objective To carry out a comprehensive and objective evaluation of viscosupplementation, so as to provide the actual judgments of effectiveness, development trends, and direction. Methods The related l iterature was reviewed, and the keys were the assessments from the international relevant advisory bodies and insurance companies and the evidence-based medicine on cl inic. Results Viscosupplementation has been gradually accepted. Although there are many different cl inical views of the viscosupplementation in the molecular weight of hyaluronan, injection dose, and the indications, intra-articular injection of hyaluronan for the treatment of osteoarthritis is well accepted. ConclusionViscosupplementation is one of the methods of treating osteoarthritis. As it has been already verified that hyaluronan iseffective in treating osteoarthritis of the knee and the periarthritis of shoulder, the hip joint injection is gradually recognized,and other small joints are going gradually.

    Release date:2016-08-31 05:44 Export PDF Favorites Scan
  • Progress in the surgical treatment of the patellar fracture

    ObjectiveTo review research progress of surgical treatment of patellar fractures.MethodsThe domestic and foreign literature about patellar fracture treatment in recent years was extensively consulted, and the advantages, disadvantages, and indications of various surgical treatments were summarized.ResultsThe patella plays an important role in knee flexion and extension activities, and the fracture significantly affects the patient’s quality of life. At present, the surgical methods include open reduction and internal fixation and patella resection. The internal fixation methods include ring/binding patella fixation, tension band wiring and improved technology, tension band wiring combined with other methods, screw fixation (including absorbable screws), steel plate fixation, and patella fixator fixation. Each surgical method has different indications, advantages, and disadvantages. Choosing an appropriate treatment plan plays a crucial role in clinical prognosis.ConclusionThere are many surgical treatments for patellar fractures. In order to improve the effectiveness and reduce postoperative complications, it is necessary to choose the most appropriate treatment strategy for the type of fracture.

    Release date:2021-08-30 02:26 Export PDF Favorites Scan
  • Progress of diagnosis and treatment of upper respiratory obstruction in patients with Treacher Collins syndrome

    ObjectiveTo summarize the progress of diagnosis and treatment of upper respiratory obstruction in patients with Treacher Collins syndrome (TCS).MethodsThe domestic and abroad literature about the diagnosis and treatment of upper respiratory obstruction in patients with TCS was extensively reviewed and analyzed.ResultsTCS is an autosomal-dominant craniofacial developmental syndrome. It is often accompanied by midface and/or mandibular hypoplasia, soft tissue hypertrophy, and other respiratory tissue developmental abnormalities, which can lead to different degrees of upper respiratory obstruction symptoms. Respiratory obstruction in patients with TCS is affected by many factors, and the obstructive degree are different. Early detection of the causes and obstructive sites and adopted targeted treatments can relieve the symptoms of respiratory obstruction and avoid severe complications.ConclusionDue to the low incidence of TCS, there is still a lack of high-quality research evidence to guide clinical treatment. Large-scale and prospective clinical studies are needed to provide new ideas for the treatment and prevention of upper respiratory obstruction.

    Release date:2019-12-23 09:44 Export PDF Favorites Scan
  • PROGRESS OF JOINT-PRESERVING PROCEDURES FOR TREATMENT OF AVASCULAR NECROSIS OF FEMORAL HEAD

    Objective To review the researches on the jointpreserving procedures for the treatment of the avascular necrosis (AVN) of the femoral head. Methods The latest original literatures about the joint-preserving procedures for the treatment of AVN of the femoral head were extensively reviewed. Results There were many surgical jointpreserving procedures to treat AVN of the femoral head, such as core decompression, bone grafting, and osteotomy. Most researchers achieved excellent clinical results by using the joint-preserving procedures to treat the early stages of AVN of the femoral head. Conclusion Treating AVN of the femoral head by the joint-preserving procedures, especially the free vascularized fibula grafting, can achieve an excellent longterm clinical outcome.

    Release date:2016-09-01 09:26 Export PDF Favorites Scan
  • 中西医结合治疗癫痫进展

    梳理中西医结合治疗癫痫的进展,探讨其意义并分析研究趋势。通过文献研究的方法,介绍中西医结合治疗癫痫的主要代表性方法、成果、进展和方向。近年来中西医结合治疗癫痫的类型主要包括:小儿癫痫、脑外伤后癫痫、脑卒中后癫痫、难治性癫痫、癫痫持续状态、未分类癫痫,偶有对特发性癫痫、糖尿病伴发癫痫、不同发作类型癫痫治疗的研究;在治疗方面,中医疗法以中药、针刺、埋线三种为主,其中中药和埋线均呈现出上升趋势,针灸的趋势则基本为水平状,其他治法均为偶见。中西医结合治疗癫痫可以提高疗效、减轻抗癫痫药物的不良反应,依从性较好,应用广泛。

    Release date:2017-07-26 04:06 Export PDF Favorites Scan
  • RESEARCH ADVANCE IN REPAIR OF PERIPHERAL NERVE DEFECT WITH ACELLULAR NERVE ALLOGRAFT

    Objective To investigate the research advance in repair of the peripheral nerve defect with an acellular nerve allograft. Methods The recent related literature was extensively and comprehensively reviewed. The methods and the effects of the allografts with acellular nerves were analyzed. Results The immunogenicity of the allograft was more significantly relieved by the chemical treatment than by the physicaltreatment. The effect of the chemical treatment on the axon regeneration was better than that of the physical treatment. Conclusion Because of the limitation of the host Schwann cell translation in the longsegment acellular nerve allografts, the effect of Schwann cells is not satisfactory and regeneration of the nerve is limited. So, the recellularized treatment with some related measures can enhance the host Schwann cell translation so that this problem can be solved. 

    Release date:2016-09-01 09:23 Export PDF Favorites Scan
  • Progress of fish collagen as novel biomedical material

    Objective To review the lately new progress of fish collagen as biomedical materials, and then analyze feasibility and risk management of its application as a substitute of collagen originated from mammals in clinical practice. Methods Based on extensive research on new application and investigation of fish collagen, the paper was prepared to bring comprehensive analysis of its research and application status, and then several key points were focused on. Results Fish collagen has been proved to be a novel collagen of rich source, low risk of virus transmission, low biological risk, less religious barrier, and high biocompatibility. Fish collagen has promising prospect when applied in clinical practice as novel collagen especially as a substitute of collagen derived from mammals. However, very few related translational medicine research of fish collagen has been reported up to now in China. Conclusion As a novel potential substitute of collagen source derived from mammals, fish collagen is concerned to be clinical feasible and necessary in translational medicine. However, massive applied basic researches should be focused on in the further investigations.

    Release date:2018-09-03 10:13 Export PDF Favorites Scan
  • Research progress on peripheral blood indexes in the prognosis of small cell lung cancer

    In recent years, many scholars have explored the clinical application value of a number of peripheral hematology indexes in tumor patients. The significant correlation of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio with the prognosis in various tumors has also been confirmed. At present, more peripheral blood indexes have been gradually applied to the evaluation of the prognosis in patients with malignant tumors. Small cell lung cancer (SCLC) is a type of highly malignant tumor and most patients are in advanced stage at the time of diagnosis. The evaluation value of tumor stage for survival is extremely limited. Therefore, this review intends to explain the relationship between various peripheral hematology indexes and the prognosis of SCLC patients, so as to provide some academic evidence for the clinical assessment of the survival of SCLC patients and formulation of appropriate treatment strategy, which may contribute to the improvement of the prognosis.

    Release date:2022-06-24 01:25 Export PDF Favorites Scan
  • Research progress on the correlation between gender differences and the incidence of knee osteoarthritis

    Knee osteoarthritis (KOA) is one of the common degenerative joint diseases, which is more common in the middle-aged and elderly population. It shows significant gender differences, with a significantly higher incidence rate in women than in men, seriously affecting the quality of life of patients. However, there are few research reports on the correlation between gender differences and the incidence of KOA both domestically and internationally. Therefore, this article will summarize and analyze the potential causes of gender differences related to the incidence of KOA from five aspects: hormone levels, anatomical biomechanical characteristics, genes, obesity, and exercise-muscle factors. Through a comprehensive review of research progress, the aim is to provide a theoretical basis for gender based personalized treatment of KOA in clinical practice.

    Release date:2024-05-28 01:17 Export PDF Favorites Scan
  • 亚砷酸治疗实体瘤临床研究进展

    由于亚砷酸(As2O3)对急性早幼粒细胞性白血病有非常高的治愈率和缓解率,大量细胞和动物实验证实亚砷酸对实体瘤也有较强的抑制杀伤作用,许多学者试图将亚砷酸应用于抗实体瘤。一些学者已经开始应用亚砷酸治疗实体瘤的临床试验,发现单用亚砷酸或联合常规治疗方案治疗实体瘤有一定效果。本文就亚砷酸在治疗实体瘤方面的临床研究进行了综述。

    Release date:2016-09-08 10:00 Export PDF Favorites Scan
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