目的 探讨特发性结肠穿孔的治疗方法及成因。方法 结合文献分析2001~2009年期间我院收治的特发性结肠穿孔患者的诊治经过。结果 共收治特发性结肠穿孔9例,占同期结肠穿孔患者的28.1%(9/32),其中5例穿孔(5/9)发生在乙状结肠。修剪破口后直接缝合者2例,行结肠双腔造瘘者7例。术后死亡3例。结论 特发性结肠穿孔好发于乙状结肠,与其解剖和生理上的特点有关。不明原因结肠穿孔的患者要想到本病的可能。及时、合理的手术治疗,仔细周到的术后管理是治疗成功的关键。
目的 探讨老年患者特发性结肠穿孔的临床特点。方法回顾性分析我科2000年5月至2010年5月期间收治的28例特发性结肠穿孔老年患者的临床资料。 结果28例患者中男16例,女12例; 年龄60~87岁,中位年龄69.2岁。所有患者表现为急性腹痛或腹膜炎; 术前5例确诊,23例误诊; 均行急诊剖腹探查手术,穿孔位于乙状结肠与直肠交界处有18例,位于降结肠4例,乙状结肠中段5例,直肠上段1例。 8例行穿孔部位结肠外置,再择期行二次手术; 16例行乙状结肠下段及直肠上段切除、结肠造瘘术; 4例行病变部位一期切除吻合、回盲部导管减压引流术。术后病理报告: 结肠壁局灶性炎性反应坏死,穿孔边缘清楚,肌层断裂整齐,黏膜剥脱,其中10例伴黏膜溃疡。 住院时间为2~4周,平均2.6周。 20例患者痊愈出院,死亡8例,其中4例死于中毒性休克,2例因吻合口漏并发腹腔脓肿死于严重感染和多器官功能衰竭,2例死于并发肺部感染、呼吸衰竭。 结论诊断性腹腔穿刺及CT检查对老年患者的特发性结肠穿孔诊断极为重要,一旦确诊或疑诊应尽早手术治疗。
目的 探讨腹腔镜下修补医源性结肠穿孔的可行性和手术技巧。方法 回顾性分析我院2007年 10月至2009年12月期间腹腔镜下修补医源性结肠穿孔手术6例患者的临床资料,其中诊断性肠镜检查结肠穿孔2例,治疗性肠镜结肠穿孔4例。结果 6例患者均顺利完成腹腔镜下手术, 无中转开腹。3例患者全腹腔镜下完成结肠穿孔修补,2例因破口较大在腹腔镜辅助下完成结肠穿孔修补,1例乙状结肠癌患者肠镜检查结肠穿孔后同时行腹腔镜下乙状结肠癌根治手术,术后未发生吻合口漏、残余感染等并发症。结论 腹腔镜下修补医源性结肠穿孔安全、可靠,临床效果肯定。
ObjectiveTo analyze the surgical effect, postoperative complications and effects on the body inflammatory response of laparoscopic gastroduodenal perforation repair, and to further evaluate the efficacy of laparoscopic perforation repair. MethodsWe retrospectively analyzed the clinical data of 123 patients with gastroduodenal ulcer perforation treated between February 2010 and February 2015. Among the patients, 65 underwent laparoscopic gastroduodenal ulcer perforation repair (laparoscopic group), and 58 underwent routine open gastroduodenal ulcer perforation repair (open group). Then, we compared the surgical effects (average bleeding volume, ambulation time, postoperative ventilation time, postoperative hospital stay), postoperative complications (wound infection, wound dehiscence, gastroduodenal fistula, abdominal abscess, intestinal obstruction), inflammatory reaction[preoperative and 1, 3, 5-day postoperative white blood cells (WBC) count, peripheral blood procalcitonin (PCT), C-reactive protein (CRP)] between the two groups. ResultsPatients in both the two groups underwent the surgery successfully. No patients in the laparoscopic group were transferred to open surgery. Compared with the open surgery, surgical bleeding volume, ambulation time, anal exhaust time and postoperative hospital stay of the laparoscopic group were significantly different (P < 0.05). Postoperative complications rate of the laparoscopic group was significantly lower than that of the open group (P < 0.05). One and 3-day WBC, PCT and CRP after surgery increased obviously in both the two groups. The above three indicators on the fifth day after surgery were not significantly different from those before the surgery in the laparoscopic group (P > 0.05), while they were significantly different from those before the surgery in the open group (P < 0.05). ConclusionsCompared with open perforation repair, laparoscopic perforation repair surgery is superior for its better surgical effects, fewer postoperative complications and lighter inflammatory response. It is a safe, effective and minimally-invasive treatment for gastroduodenal perforation.
目的 探讨结肠癌和直肠癌并发肠穿孔的外科诊治方法。方法 分析13例结直肠癌并发肠穿孔患者的临床资料。结果 13例患者中4例行肿瘤所在肠段一期切除吻合术; 4例行一期病灶切除吻合术,近端肠段行外置双管造瘘术; 2例切除肿瘤所在肠段,近端行端式结肠造瘘术,远端行封闭(Hartmann)术; 3例行单纯肠造瘘术。术后并发症发生率为46.15%(6/13),手术死亡率为15.38%(2/13)。结论 重视对结直肠癌并发肠穿孔的认识及选择合适的手术方式是减少并发症、提高疗效的重要措施。