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Nutritional Support for Functional Delayed Gastric Emptying after Abdominal Operation

【摘要】目的 探讨腹部手术后功能性胃排空障碍的营养支持。方法 对我院1997年1月至2004年2月收治的27例腹部手术后胃排空障碍患者的临床资料进行回顾性分析。结果 单纯肠内营养支持8例（29.6%），肠内、肠外联合营养支持10例（37.0%），单纯肠外营养支持9例（33.3%），分别于术后平均15、20及23 d恢复胃动力。结论 肠内营养在功能性胃排空障碍的治疗中具有重要作用。

Research progress of measures of postoperative pulmonary complications after abdominal surgery

ObjectiveTo summarize the methods to prevent pulmonary complications in patients underwent abdominal surgery during perioperative period and provide reference for the prevention of postoperative pulmonary complications.MethodLiteratures on the prevention of pulmonary complications after abdominal surgery were searched and reviewed.ResultsThe prevention of pulmonary complications after abdominal surgery included preoperative measures, intraoperative measures, and postoperative measures. Preoperative measures included preoperative education, patient risk assessment, smoking cessation, and so on. Intraoperative measures included anesthetic measures and surgical measures. Postoperative measures included atomization treatment, elimination of bad feelings, early postoperative activities, and so on. In view of the different basic conditions of patients underwent abdominal surgery, the selection and emphasis of preventive measures were also different.ConclusionThe prevention of postoperative pulmonary complications after general abdominal surgery should not only take preventive measures in perioperative period, but also should carry out individual management according to the patient’s condition and general conditions.

几丁糖预防腹部术后肠粘连的疗效观察

目的 观察几丁糖预防腹部术后肠粘连的效果。 方法 2000 年1 月－ 2008 年12 月，收治再次剖腹手术患者127 例，其中69 例前次术中应用几丁糖（应用组），男41 例，女28 例，年龄13 ～ 82 岁。前次手术原因：胃肠、胆道及胰腺部癌30 例，弥漫性腹膜炎21 例，外伤性血腹8 例，粘连性肠梗阻及腹茧症6 例，大肠破裂4 例。58 例前次术中未应用几丁糖（对照组），男34 例，女24 例，年龄15 ～ 84 岁。前次手术原因：胃肠、胆道及胰腺部癌24 例，弥漫性腹膜炎18 例，外伤性血腹7 例，粘连性肠梗阻及腹茧症6 例，大肠破裂3 例。两组患者再次手术距前次手术时间为3 个月～ 9年。 结果 根据Phillips 和仲剑平分级标准评定粘连程度：应用组获0 级61 例，Ⅰ级6 例，Ⅱ级2 例；对照组获Ⅰ级5 例，Ⅱ级27 例，Ⅲ级16 例，Ⅳ级10 例；两组比较差异有统计学意义（P lt; 0.01）。 结论 几丁糖是一种预防术后肠粘连的较理想生物材料。

Comparison of Patient-controlled Intravenous and Epidural Analgesia on Postoperative Complications after Abdominal and Thoracic Surgery: A Meta-Analysis

Objective　To compare the effect of intravenous and epidural analgesia on postoperative complications after abdominal and thoracic surgery. Methods　A literature search was conducted by using computerized database on PubMed, EBSCO, Springer, Ovid, and CNKI from 1985 to Jan 2009. Further searches for articles were conducted by checking all references describing postoperative complications with intravenous and epidural anesthesia after abdominal and thoracic surgery. All included randomized controlled trials (RCTs) were assessed and data were extracted by the standard of Cochrane systematic review. The homogeneous studies were pooled using RevMan 4.2.10 software. Results　Thirteen RCTs involving 3 055 patients met the inclusion criteria. The results of meta-analyses showed that, a) pulmonary complications and lung function: patient-controlled epidural analgesia can significantly decrease the incidence of pneumonia (RR=0.66, 95%CI 0.53 to 0.83) and improve the FEV1 (WMD=0.17, 95%CI 0.05 to 0.29) and FVC (WMD=0.21, 95%CI 0.1 to 0.32) of lung function after abdominal and thoracic surgery, but no differences in decreasing postoperative respiratory failure (RR=0.77, 95%CI 0.58 to 1.02) and prolonged ventilation (RR=0.75, 95%CI 0.51 to 1.13) compared with intravenous analgesia; b) cardiovascular event: epidural analgesia could significantly decrease the incidence of myocardial infarction (RR=0.58, 95%CI 0.35 to 0.95) and arrhythmia (RR=0.64, 95%CI 0.47 to 0.88) than the control group, but could not better reduce the risk of heart failure (RR=0.79, 95%CI 0.47 to 1.34) and hypotension (RR=1.21, 95%CI 0.63 to 2.29); and c) Other complications: epidural and intravenous analgesia had no difference in decreasing the risk of postoperative renal insufficient (RR=0.78, 95%CI 0.53 to 1.14), gastrointestinal hemorrhage (RR=0.78, 95%CI 0.49 to 1.23), infection (RR=0.89, 95%CI 0.70 to 1.12) and nausea (RR=1.03, 95%CI 0.38 to 2.81). Conclusions　Epidural analgesia can obviously decrease the risk of pneumonia, myocardial infarction and severe arrhythmia, and can improve the lung function after abdominal or thoracic surgery.

Clinical Diagnosis and Treatment of Abdominal Postsurgical Gastroparesis Syndrome

目的 总结腹部手术后胃瘫综合征（PGS）的病因、诊断及治疗方法。方法回顾性分析我院2003年1月至2009年3月期间行腹部手术后发生胃瘫的30例患者的临床资料。结果 PGS发生于术后5～10 d，通过临床表现、上消化道造影及胃镜检查明确诊断。全组均经营养支持、药物治疗等保守治疗后治愈，治愈时间14～62 d，平均25 d。结论 PGS是由多种因素导致的,上消化道造影及胃镜检查是诊断PGS的可靠方法,保守治疗为其主要治疗手段，应尽量避免再次手术。

Effect of systemic immune-inflammatory index on postoperative pulmonary complications in patients undergoing abdominal surgery: a retrospective observational study

ObjectiveTo determine the predictive value of preoperative systemic immune-inflammatory index (SII) regarding the development of postoperative pulmonary complications (PPCs) after abdominal surgery.MethodsThisretrospective study involved 433 patients undergoing elective abdominal surgery. Logistic regression risk model was used to evaluate the prognostic value of SII. We drew the receiver-operating characteristic (ROC) curve and calculated the area under the ROC curve to compared the predictive ability of SII, platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), and monocyte-to- lymphocyte ratio (MLR).ResultsThe independent risk factors of PPCs were preoperative respiratory diseases, preoperative history of chronic liver disease, maintenance of intravenous or inhalation anesthesia, and intraoperative infusion of more colloid (P<0.05). However, SII, PLR, NLR, and MLR did not predict the occurrence of PPCs, and they also did not predict ≥3 grade of PPCs (AUC<0.60, P>0.05).ConclusionsPreoperative SII is not a prognostic biomarker of PPCs occurrence in patients undergoing elective abdominal surgery. Other biomarkers, such as PLR, NLR, and MLR, also have no predictive value for the PPCs in these patients.

Effect of a Preoperative Pain Education Program on Postoperative Pain Management after Abdominal Surgery

Objective　To evaluate the effects of a preoperative pain education program on patients’ knowledge of postoperative pain management, measures taken for such pain management and the actual postoperative pain. Methods　A total of 84 patients undergoing abdominal surgery were non-randomly divided into two groups, 42 in each group. Patients in group A received routine preoperative care and 30 minutes of education about pain management, while patients in group B received routine preoperative care only. All patients completed the Postoperative Pain Management Questionnaire on the second postoperative day. Results　Patients in group A achieved higher scores for their knowledge about postoperative pain management than those in group B (Plt;0.05). More patients in group A took non-medical pain relief methods after surgery (Plt;0.05); and patients in group A were able to use the PCA pump more correctly than those in group B (Plt;0.05). No significant differences were observed between the two groups in the frequency of asking for analgesics or their pain score when they requested analgesics (Pgt;0.05). The average score for postoperative pain was lower for group A compared to group B (Plt;0.05). Conclusions　A program of preoperative pain education can improve patients’ knowledge of postoperative pain management and encourage them to participate actively in such pain management, so as to further relieve the postoperative pain.

上腹部手术后并发的心律失常

The Relationship Between Hypertension and Perioperative Complications in patients Undergoing Abdomen Surgery

Objective To evaluate whether to defer abdomen surgery in patients having poorly controlled or untreated hypertension before operation. MethodsThe perioperative clinical data of 531 patients with hypertension in our hospital from January 1997 to December 1998 was retrospectively analyzed. ResultsThe modility of perioperative hypertensive events was not significantly different, between controlled and uncontrolled patients with grade one and grade two（Pgt;0.05）. In grade three and systolic hypertension, certain complications in patients with poorly controlled hypertension were higher than in those with wellcontrolled hypertension（P＜0.05）. Conclusion The patients with grade one and grade two hypertension are not at increased operative risk. In patients with grade three and systolic hypertension, perioperative complications are increased and elective surgery should be postponed until their blood pressure is brought under 24/14.7 kPa （180/110 mm Hg） over 1 to 2 weeks.

Effect of Preoperative Anxiety on Postoperative Pain and Analgesics Requirements in Patients Undergoing Abdominal Surgery

【摘要】 目的 研究全身麻醉腹部手术患者术前焦虑对术后疼痛、镇痛药用量及对术后镇痛满意度的影响。 方法 选取2009年8月-2010年4月68例ASAⅠ～Ⅱ级，拟行气管插管全身麻醉的腹部手术患者，术前采用状态-特质焦虑量表和抑郁评分量表进行焦虑程度的测评，术后观察VAS疼痛评分、总的镇痛药用量以及患者对镇痛的满意度，分析术前焦虑与术后VAS评分、镇痛药用量及镇痛满意度的相关性。 结果 68例受试者术前STAI为50±13，BDI为16±13，术后VAS评分为4.0±2.1，术后24 h镇痛药芬太尼的用量为（0.80±0.21） mg；术后镇痛药用量、患者镇痛满意度评分与术前STAI明显相关（r=0.68和r=-0.88，Plt;0.01）。术后VAS评分与术前STAI及BDI也有一定的相关（r=0.35和r=0.3）。 结论 术前焦虑程度可以影响腹部手术患者对镇痛治疗的满意度， 显著增加镇痛药用量。【Abstract】 Objective To investigate the effect of preoperative anxiety on postoperative pain, amount of analgesics and satisfaction of postoperative pain relief for patients undergoing abdominal surgery with general anesthesia. Methods A total of 68 patients undergoing abdominal surgery with general anesthesia from August 2009 to April 2010 were selected (ASA I-II). Preoperational anxiety levels were evaluated using State-Trait Anxiety Inventory (STAI) and Beck Depression Inventory (BDI) and postoperative VAS pain score, the total amount of analgesics used and satisfaction of pain relief were observed. The relationship between preoperative anxiety and post-operative VAS score, and total amount of analgesics used and satisfaction of pain relief were analyzed. Results The mean STAI and BDI of 68 samples were 50±13 and 16±13, respectively; the mean postoperative VAS was 4.0±2.1, and the mean amount of analgesics fentanyl used in 24 hours after the operation was (0.80±0.21) mg; the amount of post-operative analgesics used and the satisfaction of pain relief of the patients were found to be highly related to pre-operative STAI (r=0.68, -0.88; Plt;0.01). Post-operative VAS score was also related to preoperational STAI and BDI (r=0.35, 0.3). Conclusion Preoperative anxiety is closely related to the postoperative analgesics and satisfaction of pain relief for patients who had abdominal operation. Severe preoperative anxiety can significantly increase the amount of postoperative analgesics used and dissatisfaction of pain relief.