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find Keyword "芬太尼" 53 results
  • 腹腔镜手术中应用靶控输注瑞芬太尼和丙泊酚的价值

    目的 探讨靶控输注瑞芬太尼和丙泊酚在腹腔镜手术中的效果,以指导临床治疗工作。 方法 2008年6月-2009年7月,选取190例行择期腹腔镜手术的患者,随机分为两组,观察组(95例)应用靶控输注瑞芬太尼和丙泊酚;对照组(95例)常规泵注瑞芬太尼和丙泊酚。观察手术过程中血流动力学的变化及术后患者的状况。 结果 观察组患者手术中收缩压、舒张压及心率变化较对照组变化平稳。观察组术后呕吐发生率明显低于对照组(Plt;0.05)。 结论 靶控输注瑞芬太尼和丙泊酚,能维持腹腔镜手术患者麻醉平稳,副反应小,适合在临床应用。

    Release date:2016-09-08 09:47 Export PDF Favorites Scan
  • Associated Medication of FentanylPropofol and MidazolamPropofol and Gastroscopy

    目的:讨论胃镜检查中更加舒适的一种镇静镇痛方法。方法:芬太尼-异丙酚为Ⅰ组,咪唑安定-异丙酚组为Ⅱ组。观察记录各组术中的反应、胃镜操作时间、麻醉药物起效时间、苏醒时间和清醒时间,检查前中后BP、HR和SpO2的变化,及术后问卷调查。结果:Ⅰ组药物的起效快,受检者苏醒及清醒时间短,术中不适反应少,与Ⅱ组比较有统计学意义(Plt;0.01)。结论:镇静无痛苦胃镜检查中芬太尼-异丙酚联合用药更舒适。

    Release date:2016-09-08 10:01 Export PDF Favorites Scan
  • Effect of Postoperative Patient-Controlled Epidural Analgesia with Different Doses of Sufentanil after Cesarean Section

    【摘要】 目的 观察不同剂量的舒芬太尼用于剖宫产术后硬膜外自控镇痛的效果比较。 方法 将2009年4-11月60例硬膜外麻醉下行剖宫产手术术后的患者随机分为三组,术后镇痛液A组采用0.125%罗哌卡因复合0.3 μg/mL舒芬太尼;B组为0.125%罗哌卡因复合0.4 μg/mL舒芬太尼;C组0.125%罗哌卡因复合0.5 μg/mL舒芬太尼,观察三组患者的术后镇痛效果(视觉模拟法评分,即VAS评分)及不良反应。 结果 A组VAS评分高于B组和C组,B组VAS评分高于C组(Plt;0.05)。三组患者术后恶心呕吐、运动阻滞、嗜睡及肠蠕动抑制等并发症无统计学差异(Pgt;0.05)。 结论 0.125%罗哌卡因复合0.5 μg/mL舒芬太尼以4 mL/h持续输注用于剖宫产术后患者自控硬膜外镇痛术后疼痛VAS评分最小,患者镇痛满意度最高。【Abstract】 Objective To observe the effect of postoperative patient-controlled epidural analgesia (PCEA) with three different doses of sufentanil combined with 0.125% ropivacaine after cesarean section. Methods Data was collected from April 2009 to November 2009. Sixty patients after cesarean section under continuous epidural anesthesia were randomly divided into three different groups.Group A was given sufentanil 0.3 μg/mL and 0.125% ropivacaine for PCEA, group B was given sufentanil 0.4 μg/mL and 0.125% ropivacaine, group C was given sufentanil 0.5 μg/mL and 0.125% ropivacaine. The analgesia effects were evaluated by the visual analogue scales (VAS). Side effects were also recorded. Results The VAS scores were significantly the highest in group A than that in group B and group C, the VAS scores in group B were higher than that in group C (Plt;0.05). The incidence of side effects, such as postoperative nausea and vomiting, lethargy, and pruritus, was not significant among the three groups (Pgt;0.05). Conclusion 0.5 μg/ mL sufentanil and 0.125% ropivacaine recommended for PCEA with background 4 mL/h is safe and effective for patients after cesarean section.

    Release date:2016-09-08 09:50 Export PDF Favorites Scan
  • The Effect of Flurbiprofen Ester on Thyroid Surgery Patients With PropofolRemifentanil Anesthesia

    目的:探讨甲状腺手术中氟比洛芬酯对丙泊酚—瑞芬太尼麻醉效果的影响。方法:将210例择期丙泊酚—瑞芬太尼麻醉下行甲状腺手术患者随机分为对照组和氟比洛芬酯组,每组105例。于切皮前30 min,对照组静脉注入等量生理盐水10mL,氟比洛芬酯组经静脉注入氟比洛芬酯注射液100 mg。分别记录患者麻醉前10 min (T0)、切皮时(T1)、切皮后10 min (T2)、切除腺体时 (T3)以及拔管时 (T4) 的血流动力学 (SBP、DBP、HR) 的变化以及术后口述描述评分(VRS)。结果:与对照组比较, 氟比洛芬酯组T14时SP、DP均降低,两组差别有统计学意义(Plt;005)。氟比洛芬酯组离开手术室时无痛率明显高于对照组,两组差别有统计学意义(Plt;005)。结论:氟比洛芬酯对丙泊酚—瑞芬太尼麻醉下行甲状腺手术患者血流动力学影响小,且减轻术后疼痛,术后恢复更为舒适。

    Release date:2016-08-26 02:21 Export PDF Favorites Scan
  • Preemptive Analgesia of Ketamine on Remifentanil Induced Acute Postoperative Pain

    【摘要】 目的 观察在腹腔镜胆囊切除术中,氯胺酮超前镇痛对瑞芬太尼麻醉后急性疼痛的影响。 方法 2009年10月-2010年1月,将择期行腹腔镜胆囊切除术患者90例,随机分为对照组(C组)、氯胺酮超前镇痛组(K组)、氯胺酮术毕镇痛组(K1组),每组30例。所有患者均采用瑞芬太尼复合丙泊酚静脉麻醉,K组在切皮前静脉给予氯胺酮0.5 mg/kg,K1组在关腹前静脉给予氯胺酮0.5 mg/kg,C组不给予任何药物。记录术毕患者麻醉恢复情况,各时间点疼痛程度。 结果 K组、K1组躁动发生率均明显低于C组(Plt;0.05);术后2、4、8、24 h,K组VAS评分及镇痛药使用率明显低于C组和K1组(Plt;0.05)。 结论 氯胺酮超前镇痛能明显降低瑞芬太尼术后疼痛,并且不增加并发症发生率。【Abstract】 Objective To evaluate the preemptive analgesia of ketamine on remifentanil induced acute postoperative pain after laparoscopic cholecystectomy. Methods Ninty patients scheduled for laparoscopic cholecystectomy between october 2009 to Jannary 2010 were randomly assigned to three groups (n=30). Group K was administrated with 0. 5 mg/kg ketamine intravenously before skin incision, and Group K1 were administrated with 0. 5 mg/kg ketamine intravenously before abdominal closure, while Group C received nothing. The recovery and the side effects were recorded, the VAS at two, four, eight and 24 hours after surgery, and the use of anodyne were recorded. Results The incidence of restlessness in Groups K and K1 was remarkably lower than that of Group C (Plt;0. 05). The analgesic effects two, four, eight and 24 hours after surgery were obviously better in group K than those of Group C and Group K1 (Plt;0. 05). Conclusion Ketamine can produce preemptive analgesia to relieve remifentanil-induced acute pain, and it would not increase incidence of side effects.

    Release date:2016-09-08 09:50 Export PDF Favorites Scan
  • A Clinical Trial of Low Concentration Ropivacaine Combined with Sulfentanyl Using for Labour Pain

    【摘要】目的观察低浓度罗哌卡因复合舒芬太尼用于分娩镇痛的效果。方法2007年5月8月按入选标准选择100例产妇,随机分成试验组和对照组,每组50例。试验组分娩前给予低浓度罗哌卡因加舒芬太尼,对照组不行无痛分娩,通过视觉模拟评分法等指标观察镇痛效果。结果试验组镇痛后视觉模拟评分较对照组低(Plt;0.05);两组镇痛期间血压、心率差异有统计学意义(Plt;0.05),新生儿Apgar评分比较无统计学意义(Pgt;0.05)。结论联合应用罗哌卡因和舒芬太尼用于硬膜外分娩镇痛能取得较好的效果,值得在临床中推广应用。

    Release date:2016-09-08 09:31 Export PDF Favorites Scan
  • The Safety of Using Propofol and Fentanyl in the Fiberoptic Bronchoscopic Examination

    目的:探讨丙泊酚、芬太尼用于纤支镜检查的安全性。方法:60例纤支镜检查患者分为丙泊酚组和对照组。丙泊酚组采用芬太尼1~15 μg/kg,丙泊酚1~2 mg/kg静脉麻醉,观察检查前、纤支镜进入声门后5分钟、检查后的HR、BP、RR 、SpO2变化及两组病例术中、术后的反应。结果:丙泊酚组检查中HR、BP较对照组平稳(P<0.01), RR、SpO2变化与对照组比较无明显统计学差异(P>0.05),丙泊酚组检查中、检查后不良反应少,苏醒快,患者满意。结论:丙泊酚、芬太尼用于纤支镜检查,减少了患者的恐惧与痛苦,提供了良好的检查条件,同时也是安全可行的。

    Release date:2016-09-08 10:14 Export PDF Favorites Scan
  • Etomidate Combined with Sufentanil for Laryngeal Mask Airway Insertion under the General Anaesthesia

    【摘要】 目的 观察依托咪酯乳剂复合舒芬太尼用于全麻下喉罩置入的血流动力学变化。 方法 选择2009年4月-2010年2月间,46例需全麻手术、适合使用喉罩,美国麻醉医师协会(ASA)Ⅰ~Ⅱ级,年龄18~60岁的患者,随机分为两组:依托咪酯乳剂组(E组)23 例,静脉推注咪达唑仑0.05 mg/kg,依托咪酯乳剂0.3 mg/kg;依托咪酯乳剂+舒芬太尼组(ES组)23 例,静脉推注咪达唑仑0.05 mg/kg,依托咪酯乳剂0.15 mg/kg,加舒芬太尼0.5 mg/kg,诱导后置入喉罩,记录患者诱导前、用药后1 min、喉罩置入后1 min的心率(HR)、平均动脉压(MAP)以及评估喉罩置入条件的6项指标(张口困难分级、置入喉罩困难分级、舌咽反射、干咳干呕反射、肢动反应及喉痉挛分级),同时记录呼吸暂停时间。 结果 ES组能提供更好的喉罩置入条件,且能减少舌咽反射和肢体反应, 更能保证喉罩置入时血流动力学的稳定。 结论 依托咪酯乳剂复合舒芬太尼能为全麻喉罩置入时提供更好的条件,且能保证更好的血流动力学稳定。【Abstract】 Objective To investigate the hemodynamics changes when etomidate combined with sufentanil was applied for laryngeal mask airway insertion under the general anaesthesia. Methods From April 2009 to February 2010, 46 patients requiring general anesthesia using laryngeal mask airway (LMA) (American Society of Anesthesiologists (ASA)Ⅰ-Ⅱ) aged 18-60 were randomly divided into two groups: 23 in etomidate emulsion group (group E) underwent the intravenous injection with midazolm (0.3 mg/kg) and etomidate (0.05 mg/kg); 23 in etomidate emulsion + sufentanil group (group ES) underwent the intravenous injection with etomidate (0.15 mg/kg), midazolm (0.05 mg/kg), and sufentanil 0.5 mg/kg. The patients were evaluated by six indexes of LMA insertion (mouth opening, swallowing reflex, cough reflex,vomiting reflex, body motion, and laryngospasm classification). After the anesthesia induction, LMA was inserted. The blood pressure (BP), heart rate (HR), and mean arterial pressure (MAP) were recorded before anesthesia induction one minute after the injection and one minute after LMA insertion. Meanwhile, the apnea time was recorded. Results Compared with group E, group ES offered better anesthesia for LMA insertion, less swallowing reflex and body motion, and more stable haemodynamics. Conclusion Etomidate combined with sufentanil provides good condition for LMA insertion under the general anaesthesia with steady haemodynamics.

    Release date:2016-09-08 09:24 Export PDF Favorites Scan
  • Effect of Dexmedetomidine Combined with Sufentanil on Patient-controlled Intravenous Analgesia after Hysterectomy

    目的 观察右美托咪啶复合舒芬太尼用于经腹子宫全切术后患者自控静脉镇痛(PCIA)的效果。 方法 2011年3月-2012年6月选择经腹子宫全切术患者90例,年龄39~68岁,体重48~72 kg,美国麻醉医师协会分级Ⅰ~Ⅱ级。采用随机数字表法,将患者随机分为3组,每组各30例。于手术结束即刻行PCIA。对照组(C组)采用舒芬太尼150 μg+昂丹司琼12 mg;S1组采用右美托咪定200 μg+舒芬太尼100 μg+昂丹司琼12 mg;S2组采用右美托咪定200 μg+舒芬太尼150 μg+昂丹司琼12 mg。3组均用生理盐水稀释至100 mL,负荷剂量均为舒芬太尼0.1 μg/kg,静脉镇痛泵背景输注速度2 mL/h,自控给药剂量0.5 mL,锁定时间15 min。记录术后6、12、24和48 h Ramsay镇静评分和视觉模拟评分(VAS),记录不良反应发生情况和患者对术后镇痛的满意度。 结果 3组患者均能获得较好的镇痛效果。其中C组VAS评分较低,但恶心、呕吐、皮肤瘙痒发生率升高;与C组相比,Sl组和S2组Ramsay镇静评分升高,恶心、呕吐、皮肤瘙痒发生率降低,患者满意度升高。S1组患者满意度最高;S2组VAS评分最低。3组均未发生心动过缓、低血压、过度镇静和呼吸抑制。 结论 右美托咪啶可增加经腹子宫全切术患者术后舒芬太尼自控静脉镇痛的效果,提高患者满意度,降低不良反应。

    Release date:2016-09-07 02:34 Export PDF Favorites Scan
  • Comparison of Remifentanil and Fentanyl during Induction of Pediatric Anaesthesia

    目的:观察等效剂量瑞芬太尼和芬太尼诱导气管插管对小儿血流动力学的影响。方法:40例择期行全麻患儿随机分为瑞芬太尼组和芬太尼组,麻醉诱导使用咪唑安定0.15mg/kg、丙泊酚2.5mg/kg、芬太尼2.5μg/kg或瑞芬太尼2μg/kg和维库溴铵0.1mg/kg。分别于麻醉诱导前(T0)、诱导后2min(T1)、插管后1、2min(T2、T3)记录心率、收缩压和舒张压。结果:两组诱导前血流动力学指标相似。与T0时比较,两组患儿T1时收缩压、舒张压均降低(Plt;0.05或Plt;0.01),心率均减慢(Plt;0.05或Plt;0.01);瑞芬太尼组T2.T3时收缩压、舒张压降低(Plt;0.05或Plt;0.01),心率减慢(Plt;0.05);芬太尼组T2、T3时收缩压、舒张压升高(Plt;0.05),心率增快(Plt;0.05)。与芬太尼组比较,瑞芬太尼组T1、T2和T3时收缩压、舒张压均降低(Plt;0.05),心率减慢(Plt;0.05)。结论:瑞芬太尼比等效剂量芬太尼能更好地抑制小儿全麻诱导气管插管时的心血管反应。

    Release date:2016-09-08 09:56 Export PDF Favorites Scan
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