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find Keyword "贲门癌" 33 results
  • 老年贲门癌患者经腹与经胸切除径路的比较分析

    摘要: 目的 探讨老年贲门癌患者经腹与经胸切除不同径路手术的治疗效果,总结其治疗经验。 方法 回顾性分析我科2000年1月至2005年1月对60岁以上贲门癌患者行贲门癌手术65例的临床资料,按手术径路不同分为两组,经腹贲门癌切除组:32例,男18例,女14例,平均年龄74岁;经胸贲门癌切除组:33例,男19例,女14例,平均年龄70岁。对两组患者的临床资料、术后并发症发生情况和生存率等进行比较分析。 结果 经腹贲门癌切除组患者切端癌残留2例,经胸贲门癌切除组患者手术死亡1例;经腹贲门癌切除组发生肺部并发症2例,经胸贲门癌切除组发生9例,两组患者肺部并发症比较差异有统计学意义(P=0.024);两组患者3年生存率比较差异无统计学意义(46.87% vs.42.42%,P=0.718)。 结论 经腹径路切除治疗老年贲门癌患者,符合肿瘤根治原则,具有切除彻底,安全有效和死亡率低的优点。

    Release date:2016-08-30 06:02 Export PDF Favorites Scan
  • 空肠间置术预防贲门癌术后反流性食管炎

    目的探讨贲门癌近端胃切除空肠间置术后预防反流性食管炎的效果. 方法贲门癌近端胃切除空肠间置术患者,于术后作胃镜和消化道 X线钡餐造影,48例患者于术后7天和2~3个月行连续24小时pH值监测,以评价食管反流的情况. 结果 6例术后出现反流性食管炎,发生率9.68%. 结论采用空肠间置术行消化道重建对预防贲门癌术后反流性食管炎具有良好的临床效果.

    Release date:2016-08-30 06:32 Export PDF Favorites Scan
  • Application of Round Stapler for Anterior Resection of Gastric Fundus and Cardia Cancer in Elderly Patients

    目的 探讨圆形吻合器在高龄贲门胃底癌经腹切除术中的应用。方法 回顾性分析1999年1月至2009年5月期间在我院接受圆形吻合器经腹切除术的238例70岁以上高龄贲门胃底癌患者的临床资料,并对围手术期结果进行分析。 结果 全组手术时间3~4.5 h,平均3.5 h。出血量50~1 000 ml,平均300 ml。术中并发大出血1例,给予积极止血,无术中死亡。所有病例机械吻合术后未出现吻合口漏。术后60例患者(25%)出现不同程度的并发症,其中吻合口出血2例, 左侧胸腔积液13例,肺部感染15例, 心衰3例, 肺不张2例, 心律失常10例,右侧胸腔积液15例。无围手术期死亡。术后随访3年,出现返流性食管炎45例,吻合口狭窄30例,无吻合口肿瘤复发,3年生存率为64%(152/238)。结论 应用圆形吻合器在高龄胃底贲门癌患者经腹切除术是安全、有效的。

    Release date:2016-09-08 10:54 Export PDF Favorites Scan
  • Diagnosis and Surgical Treatment of Multi-primary Esophageal Carcinoma

    Objective To study the diagnosis and surgical treatment of multi-primary esophageal carcinoma. Methods The data of 29 patients of multi-primary esophageal carcinoma were collected .The diagnosis was made by dye-staining through gastroscopy and X-ray examination.Pathological examination after operation was analyzed.Three kinds of operations were used: 22 by radical resection, 5 by partial resection and 2 by surgical exploration. Results Twenty-one patients were diagnosed before operation,8 patients were diagnosed during and after operation. Sixty-seven foci and 6 early stage patients were found. The complications were found in 7 patients.No patient died during operation. Twenty-five patients were followed up. The follow up time was 7-36 months.1-year survival rate 77.8%,3-year survival rate 41.6%. Conclusion Routine X-ray examination of esophagus, and esophageal dye-staining and/or biopsy through endoscopy are important measures for early diagnosis of multi-primary esophageal carcinoma.Prompt surgery is advised.

    Release date:2016-08-30 06:25 Export PDF Favorites Scan
  • 贲门癌术后吻合口复发癌的再手术治疗

    目的 探讨贲门癌术后吻合口复发癌再手术的可能性和适应证. 方法 再次手术采用胸腹联合切口和左胸切口,手术切除9例,术中姑息性置管2例,探查3例. 结果 术后发生严重并发症2例,无手术及院内死亡.手术切除者中2年和3年生存率分别为44.4%(4/9)和22.2%(2/9),5例分别在7个月~2年内死亡,2例失访.置管及探查者均在2~7个月内死亡. 结论 贲门癌术后吻合口复发癌再手术要求较高,须严格掌握手术适应证.如患者一般情况较好,病灶较小,无远处转移,仍可再次积极手术,尤其是首次经腹手术者为佳.

    Release date:2016-08-30 06:35 Export PDF Favorites Scan
  • Effect Comparison of the Negative Pressure Ball with Small Tube for Thoracic Drainage after Esophageal and Cardiac Cancer Surgery

    【摘要】目的观察负压球在食管癌、贲门癌术后的临床应用价值。方法1999年2009年对观察组食管癌、贲门癌术后使用负压球细管引流,对照组术后使用传统粗胶管水封瓶闭式引流,两组均286例。结果观察组在胸腔积液、第二天镇痛剂应用、引流口感染及术后住院时间等方面与对照组相比差异有统计学意义,而术后脓胸、第一天镇痛剂应用及管腔堵塞等方面与对照组相比无差异。结论负压球细管引流用于食管癌、贲门癌术后胸腔引流,创伤小,效果确切满意。

    Release date:2016-09-08 09:31 Export PDF Favorites Scan
  • 多药耐药基因和多药耐药相关蛋白基因在食管、贲门癌中的表达

    目的 探讨多药耐药基因(MDR1)和多药耐药相关蛋白基因(MRP)在食管癌、贲门癌中表达的临床意义.方法 采用逆转录-多聚酶链反应(RT-PCR),对29例食管癌、贲门癌癌组织及癌旁组织中MDR1和MRP的表达进行检测.结果 癌组织中MDR1阳性率为65.5%,高于癌旁组织中MDR1的阳性率,为37.9%(P<0.05),癌组织MDR1信使核糖核酸(mRNA)表达水平也显著高于癌旁组织(P<0.01);癌组织的MRP阳性率为48.3%,高于癌旁组织(27.6%),但无差异(P>0.05),而癌组织MRP mRNA表达水平与癌旁组织比较则有差异(P<0.05);中、低分化肿瘤的MDR1和MRP表达阳性率增高,两基因的mRNA表达水平显著高于高分化肿瘤(P<0.05).结论 食管、贲门癌具有内源性多药耐药性;MDR1和MRP表达与食管、贲门癌的组织学类型及TNM分期无关,但可反映其肿瘤组织分化不良的生物学特征.

    Release date:2016-08-30 06:35 Export PDF Favorites Scan
  • Antireflux Effects of Different Reinforcement Procedure in Mechanical Anastomosis for Esophageal and Cardiac Carcinoma

    ObjectiveTo compare the antireflux effects of lip reinforcement, His angle reconstruction with fundoplication, and mechanical anastomosis only in mechanical anastomosis for esophageal and cardiac carcinoma. MethodsOne hundred and seventysix patients with esophageal or cardiac carcinoma admitted to this hospital between March 2008 and October 2009 were included, which were divided into mechanical anastomosis group (n=42), His angle reconstruction group(n=56), and lip reinforcement group (n=78) according to the sequence of admission. Mechanical anastomosis only, mechanical anastomosis His angle reconstruction with fundoplication, and mechanical anastomosis liptype reinforcement were performed in the corresponding group, respectively. Endoscopy and biopsy were conducted to evaluate the antireflux effects on 3 months after operation. ResultsThere were no differences on the gender, age, tumor location, anastomosis site, and incision among three groups (Pgt;0.05). The reflux rates of the mechanical anastomosis group, His angle reconstruction group, and lip reinforcement group were 69.05%, 28.57%, and 14.10%, respectively. The reflux rates in the lip reinforcement group and His angle reconstruction group were significantly lower than those in the mechanical anastomosis group (χ2=37.088, P=0.000; χ2=15.833, P=0.000), moreover, the rate in the lip reinforcement group was significantly lower than that in the His angle reconstruction group (χ2=4.241, P=0.039). There was no anastomotic leakage in the lip reinforcement group and all patients safely discharged from hospital after surgery, only 2 patients had moderately anastomotic stenosis and both of them had good recovery with endoscopic dilatationl. The reflux after operation was independent of anastomosis sites (Pgt;0.05). ConclusionBoth liptype reinforcement and His angle reconstruction can improve the ability of antireflux, liptype reinforcement is better and simple to mainpulate.

    Release date:2016-09-08 04:25 Export PDF Favorites Scan
  • Two Cases Reports of Hand-Assisted Laparoscopic Radical Gastrectomy for Gastric Cancer

    ObjectiveTo investigate the feasibility of hand-assisted laparoscopic surgery in radical gastrectomy for gastric cancer. MethodsThe data of two cases undergoing hand-assisted laparoscopic radical gastrectomy for gastric cancer, including operative time, operation related complications, intraoperative bleeding volumes, number of harvested lymph nodes, postoperative complications, time to restoration of bowel function, and length of postoperative hospital stay, etc, were retrospectively analyzed. ResultsTwo patients had undergone the successful hand-assisted laparoscopic radical total gastrectomy and distal gastrectomy without operation related complications. The operative time was 310 min and 220 min, respectively. While, the intraoperative bleeding volume was 120 ml and 80 ml with the number of harvested lymph node being 38 and 52, respectively. There were no postoperative bleeding, intestinal fistula, and anastomotic leakage, etc. The patients were discharged with smooth and fully recovery. ConclusionThe application of hand-assisted laparoscopic surgery in radical gastrectomy for gastric cancer is feasible and safe. However, the effectiveness needs further exploring.

    Release date:2016-09-08 10:40 Export PDF Favorites Scan
  • 中断肋骨后外侧开胸切口施行食管、贲门癌切除术

    目的 为了减小开胸手术切口的创伤,获得良好的手术视野,探讨中断肋骨后外侧开胸切口的临床效果。方法 采用中断肋骨后外侧开胸方法施行食管、贲门癌切除、淋巴结清扫术126例;介绍该技术的要点,比较中断肋骨开胸切口法与其他保留肋骨方法的显露面积、创伤大小及手术效果。结果 本组无1例发生术后肺不张和胸壁切口出血而需再次开胸止血,患者均恢复良好。结论 中断肋骨开胸切口方法手术操作简单,手术视野显露好,且手术创伤小。

    Release date:2016-08-30 06:23 Export PDF Favorites Scan
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