Objective To explore the related risk factors for diabetic retinopathy (DR) in type 2 diabetes. Methods The clinical data of 412 type 2 diabetes patients, diagnosed between 2003 and 2010, were analyzed retrospectively. The diagnosis of DR and proliferative diabetic retinopathy (PDR) was confirmed by ophthalmoloscopy and fundus fluorescein angiography. Glycated hemoglobin A1c, glucose, insulin, and Cpeptide of fasting plasma, and 1, 2 and 3 hours postprandial plasma were measured. According to the abovementioned data, get the fluctuation of glucose, insulin and C-peptide of 1, 2 and 3 hour postprandial plasma. Results The morbidity of DR and PDR increased following the longer disease duration. Age, diabetic duration，body mass index (BMI), hypertension grade, HbA1C, fasting plasma insulin and C-peptide, 2 and 3 hours postprandial plasma glucose, 1 and 2 hours postprandial plasma insulin, 1, 2 and 3 hour postprandial plasma C-peptide, 1, 2 and 3 hours postprandial plasma glucose, insulin and C-peptide fluctuation are different statistically among non-DR group, non-PDR group and PDR group (P＜0.05). 3 hours postprandial plasma glucose and fasting plasma insulin were risk factors of DR (P＜0.05). Conclusions Postprandial plasma glucose and fasting plasma insulin were risk factors of DR. Nevertheless, postprandial insulin, fasting and postprandial C-peptide, postprandial plasma glucose, insulin and C-peptide fluctuation were useful for DR diagnosis.
ObjectiveTo compare the clinical efficacy between moisture healing therapy and multi-source therapeutic apparatus in the management of skin damage. MethodsFrom January 2012 to May 2014, 48 patients with 66 skin damages were divided into observation group (26 patients with 35 damages) and control group (22 patients with 31 damages) based on their informed consent and their own willing to choose the treatment methods. Patients in the observation group were treated with moisture dressings, while those in the control group received exposed treatment through multi-source therapeutic apparatus. Then, we compared the groups in terms of secondary infection rate, pain score, and healing time. ResultsThe secondary infection rate of the observation group was 2.9%, significantly lower than that of the control group (19.4%) (P<0.05). Grade Ⅱ and Ⅲ pain rate of the observation group was significantly lower than that of the control group (P<0.05). The damage healing time of the face, body and limbs was (10.0±1.3), (13.0±1.4), and (15±1.67) days, respectively, in the observation group, which was significantly shorter those in the control group [(16.0±2.6), (21.0±2.5), and (24.0±2.4) days] (P<0.05). ConclusionMoisture healing therapy can improve the eradication of necrotic tissue and dry gangrene, reduce the risk of infection and relieve pain of the patients as well as promote healing process and reduce the formation of scar by promoting regeneration of granulation and epithelium, which is worth clinical popularizing.
ObjectiveTo report a case of port-site metastasis (PSM) after laparoscopic treatment for borderline ovarian tumor (BOT), and to discuss the safety and efficacy of laparoscopic treatment for BOT as well as whether chemotherapy is beneficial for BOT patients. MethodsWe retrospectively studied a case of PSM after laparoscopic treatment of a micropapillary borderline ovarian tumor in August 2013, and reviewed the related literatures in PubMed and Cochrane databases from 1929 to 2014 using "port-site metastasis", "borderline ovarian tumor" , "laparoscopy" , "chemotherapy" as the subject words. ResultsAfter conservative operation and chemotherapy of "carboplatin and taxol" for 8 times, the subcutaneous nodes didn't shrink and the level of CA125 didn't reduce. Though some studies supported that laparoscopy was safe and effective for early-stage ovarian cancer and BOT, there was no high-quality evidence to help quantify the risks and benefits of laparoscopy for the management of early-stage ovarian cancer as routine clinical practice. While early researches suggested adjunctive chemotherapy benefited BOT patients, the subsequent studies indicated opposite results. Therefore, it was still controversial and a lack of high quality evidence existed. However, chemotherapy was recommended for those with high risks. ConclusionLaparotomy is still the standard treatment for ovarian tumor. For patients with low risks and requiring minimally invasive therapy, laparoscopy is an alternative choice, but it should be staged completely. For those with high risks or laparoscopy is difficult to perform, it should be converted to laparotomy as soon as possible. All these procedures should be completed by experienced and skillful gynecologic oncologists. For those with high risks, it is recommended that they should receive chemotherapy and be followed up for a long time.
根据消毒供应中心的工作内容，设计出具有供应室特点的书面交班报告，简单、实用，反映出消毒供应中心三区工作量化及特殊情况处理，便于质控管理。